Results 71 to 80 of about 5,266 (185)

SYNTHESIS AND EVALUATION OF ANTITUBERCULAR ACTIVITY OF 1, 3, 4-OXADIAZOLE DERIVATIVES

Asian Journal of Pharmaceutical and Clinical Research
Objective: The present study aimed to design, synthesize, and evaluate two novel series of 1,3,4-oxadiazole derivatives for their antitubercular activity against Mycobacterium tuberculosis H37Rv, supported by molecular docking and absorption, bio-distribution, metabolism, and excretion (ADME) predictions to identify potential lead molecules.
null NAMITHA KN, null VELMURUGAN V
openaire   +1 more source

Computational Investigation of 1, 3, 4 Oxadiazole Derivatives as Lead Inhibitors of VEGFR 2 in Comparison with EGFR: Density Functional Theory, Molecular Docking and Molecular Dynamics Simulation Studies. [PDF]

Biomolecules, 2022
Bilal MS, Ejaz SA, Zargar S, Akhtar N, Wani TA, Riaz N, Aborode AT, Siddique F, Altwaijry N, Alkahtani HM, Umar HI.   +10 more
europepmc   +1 more source

Synthesis and Characterization of New 1,3,4-Oxadiazole Derivatives from Sulfathiazole [PDF]

المجلة العراقية للصيدلة
Background: Oxadiazole are important heterocyclic compounds in organic chemistry. Methods: In this work, a series of new 1,3,4-oxadiazole moiety started from diazonium salt was synthesized.
Jassim Jassim, Aws Nejres, Laith Atiyah, Hussein Ibrahim, Zeyad Hameed   +4 more
doaj   +1 more source

Synthesis and cytotoxic activity evaluation of some new 1, 3, 4-oxadiazole, 1, 3, 4-thiadiazole and 1, 2, 4- triazole derivatives attached to phthalimide. [PDF]

Res Pharm Sci, 2021
Hassanzadeh F, Jafari E, Shojaei F, Sadeghi-Aliabadi H.   +3 more
europepmc   +1 more source

3-(3-Azabicyclo[2, 2, 1]heptan-2-yl)-1,2,4-oxadiazoles as Novel Potent DPP-4 Inhibitors to Treat T2DM

Pharmaceuticals
Background: Type 2 diabetes mellitus (T2DM) is a prevalent metabolic disease with global implications, necessitating effective management strategies.
Tatiana V. Zinevich, Ivan O. Maslov, Olga G. Kirichenko, Sergey V. Shorshnev, Maxim A. Gureev, Fedor M. Dolgushin, Yuri B. Porozov, Vladimir M. Trukhan   +7 more
doaj   +1 more source

3,3′-(Diazene-1,2-diyl)bis[4-(nitroamino)-1,2,5-oxadiazole 2-oxide]

Molbank, 2018
The nitramino derivatives of furoxans are of specific interest as precursors for the preparation of high energy salts with nitrogen-rich cations. In this communication, the 3,3′-(diazene-1,2-diyl)bis[4-(nitroamino)-1,2,5-oxadiazole 2-oxide] was prepared ...
Alexander Larin, Igor Ovchinnikov, Leonid Fershtat, Nina Makhova   +3 more
doaj   +1 more source

Synthesis and Antimicrobial Screening of Some Novel 2, 5-Disubstituted 1, 3, 4-oxadiazole Derivatives

E-Journal of Chemistry, 2011
The syntheses of series of 2, 5-disubstituted 1, 3, 4-oxadiazole derivatives are described. A total of twelve new compounds were synthesized and characterized by IR, 1H-NMR and Mass spectral data.
P. Panneerselvam, G. Geete Ganesh
doaj   +1 more source

Polymers Containing 1, 3, 4-Oxadiazole Rings for Advanced Materials

Memoirs of the Scientific Sections of the Romanian Academy, 2011
This paper presents the synthesis, properties and potential applications of new polymers containing 1, 3, 4-oxadiazole rings, tacking into account the requirements of the modern technologies. Two classes of polymers containing oxadiazole rings were approached: polyamides and polyimides.
Mariana-Dana Damaceanu, Radu-Dan Rusu, Maria Bruma   +2 more
openaire   +1 more source

Synthesis of New 1, 3, 4-Oxadiazole-Incorporated 1, 2, 3-Triazole Moieties as Potential Anticancer Agents Targeting Thymidylate Synthase and Their Docking Studies. [PDF]

Pharmaceuticals (Basel), 2020
Alam MM, Almalki AS, Neamatallah T, Ali NM, Malebari AM, Nazreen S.   +5 more
europepmc   +1 more source

Novel 3'-Substituted-1',2',4'-Oxadiazole Derivatives of 18βH-Glycyrrhetinic Acid and Their O-Acylated Amidoximes: Synthesis and Evaluation of Antitumor and Anti-Inflammatory Potential In Vitro and In Vivo. [PDF]

Int J Mol Sci, 2020
Markov AV, Sen'kova AV, Popadyuk II, Salomatina OV, Logashenko EB, Komarova NI, Ilyina AA, Salakhutdinov NF, Zenkova MA.   +8 more
europepmc   +1 more source