Results 21 to 30 of about 5,266 (185)

Síntese e modificações de derivados heterocíclicos de D-arabinose: potenciais inibidores de glicose-6-fosfato isomerase e de glicosamina-6-fosfato sintase Synthesis and modifications of heterocyclic derivatives of D-arabinose: potential inhibitors of glucose-6-phosphate isomerase and glucosamine-6-phosphate synthase

Química Nova, 2008
The synthesis of -5-(D-arabino-1,2,3,4-tetrahydroxybutyl)tetrazole and -2-(D-arabino-1,2,3,4-tetra-acetoxybutyl)-5-methyl-1,3,4-oxadiazole from D-arabinose is described.
Renato Márcio Ribeiro Viana, Maria Auxiliadora Fontes Prado, Ricardo José Alves   +2 more
doaj   +1 more source

Synthesis And Biological Activities Of 1, 3, 4-Oxadiazole Derivatives: A Review Of Literature. [PDF]

International Journal of Advanced Research, 2018
A series of derivatives of 1, 3, 4-oxadiazole having verities of biological activities can be synthesised by various methods. The activities include anticancer, antimicrobial, anti- inflammatory, anti- HIV, anti tubercular, anti diabetic, antifungal etc.
Baijika P, Marathakam, Akash, Midhula C C, Shadiha Saheed, K.   +3 more
openaire   +2 more sources

5-(Adamantan-1-yl)-3-[(4-benzylpiperazin-1-yl)methyl]-1,3,4-oxadiazole-2(3H)-thione

Acta Crystallographica Section E, 2012
The molecule of the title compound, C24H32N4OS, is a functionalized 1,3,4-oxadiazole-2-thione with substituted piperazine and adamantanyl substituents attached at the 3- and 5-positions, respectively, of the oxadiazole spacer with an approximately C ...
Ali A. El-Emam, Nasser R. El-Brollosy, Mohamed I. Attia, Mohammed Said-Abdelbaky, Santiago García-Granda   +4 more
doaj   +1 more source

Synthesis of a series of novel tetra-tert-butylcalix[4]arene linked to 1,2,4-triazole and 1,3,4-oxadiazole derivatives

Acta Chimica Slovenica, 2016
A series of tetra-tert-butylcalix[4]arene linked to 1,2,4-triazole-5-thiones and 1,3,4-oxadiazole-5-thiones derivatives at lower rim were synthesized by the reaction of 1,2,4-triazole-5-thione and 1,3,4-oxadiazole-5-thione  with 5,11,17,23-tetra-tert ...
Karim Akbari Dilmaghani, Zahra Dono Ghezelbash   +1 more
doaj   +1 more source

4-Amino-3-(1-{[amino(3-methyl-2-oxido-1,2,5-oxadiazol-4-yl)methylene]hydrazinylidene}ethyl)-1,2,5-oxadiazole 2-Oxide

Molbank, 2022
Functionally substituted 1,2,5-oxadiazole 2-oxides (furoxans) are important pharmaceutical scaffolds used for the preparation of various pharmacologically active substances.
Margarita A. Epishina, Alexander S. Kulikov, Leonid L. Fershtat   +2 more
doaj   +1 more source

Recent advances and prospects for high‐efficiency blue hot exciton organic light‐emitting diodes

FlexMat, EarlyView.
Blue organic light‐emitting diodes (OLEDs) face great challenges in achieving the balance between color purity, device efficiency, and stability. Hot exciton materials offer a solution by rapidly converting non‐emissive triplet excitons into singlet ones through a high‐lying reverse intersystem crossing process.
Xiaoen Shi, Shuyuan Ge, Futong Liu, Ping Lu   +3 more
wiley   +1 more source

The Identification and synthesis of metabolites of 4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide

Research Results in Pharmacology
Introduction: 4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide is a new selective type II carbonic anhydrase inhibitor with local action through instillation into the eyes. For a complete pharmacokinetic study of this drug, it is necessary to detect
Alexander L. Khokhlov, Ilya I. Yaichkov, Anton A. Shetnev, Valeria A. Panova, Julia A. Efimova, Sergey A. Ivanovskiy, Mikhail K. Korsakov, Nikita N. Volkhin, Sergey S. Petukhov   +8 more
doaj   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Synthesis and Characterization of some New 1,3,4-Oxadiazole derivatives based on 4-amino benzoic acid

مجلة بغداد للعلوم, 2016
Various of 2,5- disubstituted 1,3,4-oxadiazole (Schiff base, ?- lactam and azo) were synthesized from 2,5-di (4,4?-amino-1,3,4-oxadiazole which usequently synth-esized from mixture of 4- amino benzoic acid and hydrazine arch of polyphosphorus acid.
Baghdad Science Journal
doaj   +1 more source

Diazole and triazole derivatives of castor oil extract: synthesis, hypoglycemic effect, antioxidant potential and antimicrobial activity

Grasas y Aceites, 2020
The ricinoleate triglyceride was extracted from castor-oil seeds grown in Algeria and isolated by catalytically methanolyse to methyl ricinoleate.
F. Taieb Brahimi, F. Belkhadem, B. Trari, A. A. Othman   +3 more
doaj   +1 more source