Toxicological Evaluation of Anti-Scrapie Trimethoxychalcones and Oxadiazoles
Anais da Academia Brasileira de Ciências, 2015 An altered form of the cellular prion protein, the PrPScor PrPRes, is implicated in the occurrence of the still untreatable transmissible spongiform encephalopathies.
CLAUDIA P. FIGUEIREDO +10 more
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A Graphene Acid - TiO2 Nanohybrid as Multifunctional Heterogeneous Photocatalyst for the Synthesis of 1,3,4-Oxadiazoles [PDF]
, 2022 The immobilization of TiO2 nanoparticles on graphene acid (GA), a conductive graphene derivative densely functionalized with COOH groups, is presented.
Alemán Lara, José Julián +5 more
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Synthesis, characterization and antioxidant activity studies of new coumarin tethered 1,3,4-oxadiazole analogues [PDF]
, 2021 The present work describes the synthesis of a series of substituted 3-(5-phenyl-1,3,4-oxadiazol-2-yl)-2H-chromen-2-ones 7(a-j) using substituted aldehydes with analogues of hydrazine hydrates by grinding technique in the presence of Iodine which helps in
Ajay Kumar, K. +3 more
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Crystal structure of 2-(adamantan-1-yl)-5-(3,5-dinitrophenyl)-1,3,4-oxadiazole, C18H18N4O5 [PDF]
, 2022 C18H18N4O5, monoclinic, P21/c (no. 14), a = 11.7553(8) Å, b = 6.4876(4) Å, c = 22.3442(15) Å, β = 91.263(7)°, V = 1703.64(19) Å3, Z = 4, Rgt (F) = 0.0531, wRref (F 2) = 0.1376, T = 160 K.
Al-Wahaibi, Lamya H +3 more
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Journal of Inflammation Research, 2021 The study investigated the effect 5-[(naphthalen-2-yloxy) methyl]-1,3,4-oxadiaszole2-thiol (B3) in animal model of acute epileptic shock.The pharmacokinetics profile of B3 was checked through SwissADME software. The binding affinities of B3, diazepam, and flumazenil (FLZ) were obtained through Auto Dock and PyRx.
Muhammad Faheem +5 more
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Synthesis a Number of Heterocyclic Compounds and some of chalcones Derived From Levofloxacin
Tikrit Journal of Pure Science, 2023 The hydrazide (1) was used as synthone for the following Compound pyridazine-3,6-dione (2) by reaction of hydrazide (1) with maleic anhydride and Compound phthalazine-1,4-dione (3) by the reaction of hydrazide (1) with phthalic anhydride.
Ekram Abdullah Basheer +2 more
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Preliminary structure-activity relationship studies on some novel s-substituted aliphatic analogues of 5-{1-[(4- chlorophenyl) sulfonyl]-3-piperidinyl}-1, 3, 4-oxadiazol-2-yl sulfide [PDF]
, 2016 Purpose: To study the structure-activity relationships of synthetic multifunctional sulfides through evaluation of lipoxygenase and anti-bacterial activities.Methods: S-substituted derivatives of the parent compound 5-(1-(4- chlorophenylsulfonyl ...
Abbasi, M. Athar +5 more
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Shaping 1,2,4-Triazolium Fluorinated Ionic Liquid Crystals [PDF]
, 2023 The synthesis and thermotropic behaviour of some di-alkyloxy-phenyl-1,2,4-triazolium trifluoromethane-sulfonate salts bearing a seven-carbon atom perfluoroalkyl chain on the cation is herein described. The fluorinated salts presenting a 1,2,4-triazole as
Buscemi S. +5 more
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E-Journal of Chemistry, 2011 A series of new 3-isoxazoline substituted phthalazine methylsulfonyl-oxadiazoles were prepared from methyl 2-(4-oxo-3,4-dihydrophthalazin-1-yl) acetate.
A. M. Sridhara +5 more
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Pharmaceuticals, 2021 A current trend in the quest for new therapies for complex, multifactorial diseases, such as diabetes mellitus (DM), is to find dual or even multi-target inhibitors.
Ádám Sipos +8 more
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