Results 21 to 30 of about 3,269 (232)

Toxicological Evaluation of Anti-Scrapie Trimethoxychalcones and Oxadiazoles

Anais da Academia Brasileira de Ciências, 2015
An altered form of the cellular prion protein, the PrPScor PrPRes, is implicated in the occurrence of the still untreatable transmissible spongiform encephalopathies.
CLAUDIA P. FIGUEIREDO, NATALIA C. FERREIRA, GISELLE F. PASSOS, ROBSON DA COSTA, FERNANDA S. NEVES, CLARICE S.C. MACHADO, ALESSANDRA MASCARELLO, LOUISE D. CHIARADIA-DELATORRE, PATRÍCIA D. NEUENFELDT, RICARDO J. NUNES, YRAIMA CORDEIRO   +10 more
doaj   +1 more source

A convenient synthesis of 1,3,4-thiadiazole and 1,3,4-oxadiazole based peptidomimetics employing diacylhydrazines derived from amino acids [PDF]

, 2010
Synthesis of novel orthogonally protected 1,3,4-thiadiazole and 1,3,4-oxadiazole tethered dipeptide mimetics is described. Both the heterocycles are prepared via a set of diacylhydrazines derived from amino acids.
Lamani, R.S., Nagendra, G., Narendra, N., Sureshbabu, V.V.   +3 more
core   +1 more source

Heterocyclic Compounds as Dipeptidyl Peptidase-IV Inhibitors with Special Emphasis on Oxadiazoles as Potent Anti-Diabetic Agents

Molecules, 2022
Dipeptidyl peptidase-IV (DPP-IV) inhibitors, often known as gliptins, have been used to treat type 2 diabetes mellitus (T2DM). They may be combined with other medications as an additional treatment or used alone as a monotherapy.
Badrud Duza Mohammad, Mirza Shahed Baig, Neeraj Bhandari, Falak A. Siddiqui, Sharuk L. Khan, Zubair Ahmad, Farhat S. Khan, Priti Tagde, Philippe Jeandet   +8 more
doaj   +1 more source

Identification and characterization of antibacterial compound(s) of cockroaches (Periplaneta americana) [PDF]

, 2017
Infectious diseases remain a significant threat to human health, contributing to more than 17 million deaths, annually. With the worsening trends of drug resistance, there is a need for newer and more powerful antimicrobial agents.
A Brüning, A Fodor, A Husain, A Idhayadhulla, A Kaplan, A Nemeikaitė-Čėnienė, A Pantosti, A Pawellek, A Rauf, A Richters, A Rico, A Sakunphueak, AJ Alanis, AM Alanazi, AM Carvalho, AM Griggs, AS Mayhoub, Ayaz Anwar, B Combourieu, B Sadek, B Villemagne, B Zarzycka, BE Bilich, BE Brown, BL Ginsborg, BV Le, C Amutha, C Rademacher, C Shiota, CA Morgan, CH Yen, CL Yuan, CMM Gómez, CT Makowski, D Duś, D Mehetre, D Raffa, D Vergara, DA Pisanenko, DJ Hardick, DT Youssef, E Braud, E Clynen, E Oberbauer, E Pery, E Rosatelli, EA Musad, EC Kormann, EM Flefel, EV Verbitskiy, F Puig-Basagoiti, FN Alvarez, FT Hatch, FZ Mharti, G Devasahayam, G Engelsma, G Liu, G Ramdani, G Ren, G Schlewer, G Şahin, GN Vassilev, H Chikhale, H Hatano, H Hussain, H Istanbullu, H Li, H Niaz, H Smetana, H Wang, HB Shin, HY Chen, I Karakaya, I Orhan, IC Zampini, J Győrfi, J Han, J La, J Mareddy, JD Guzman, JF Sun, JL Vennerstrom, JM Ontoria, JP Rappai, JR Bauquier, JW Weaver, JY Yang, K Iwasa, K Philip, K Tangdenpaisal, K Wada, KW Leal, KW Park, L Sun, LJ Huang, M Akhter, M al-Rashida, M Amiche, M Brunskole Švegelj, M Gökce, M Jahangir, M Ma, M Miyazawa, M Pawelczap, M Sagheer, M Salzet, M Zhu, MA Aziz-ur-Rehman Abbasi, MA Orabi, MC Enright, MD Bachi, MH Metz-Boutigue, MIC De Troconis, MJ Arrowood, MJ Frederico, MM Alam, MM Khafagy, MN Zemtsova, MT Mackmull, Muhammad Raza Shah, N Desplaces, N Mashhoon, N Sunduru, N Özbek, NA Khan, NA Khan, NA Lack, Naveed Ahmed Khan, ND Eddington, NG Anthony, NK Roy, NR Gonewar, O Perwitasari, OO Ajani, OO Peter, P Armati, P Bulet, P Chen, P Deprez, P Funk, P Kumar, P Nordmann, P Samadhiya, PB Savage, Peter J. Heard, PL Taylor, Q Zheng, QC Fu, R Bonnett, R Bonnett, R De Simone, R Ruckli, R Wilson, RA Tapia, RL Groves, Ruqaiyyah Siddiqui, S Antoniou, S Bondock, S Celikler, S Cesarini, S Elliott, S Ganguli, S George, S Indumathi, S Kasai, S Lee, S Minami, S Nagarajan, S Wirth, S Yang, SA Lujan, Salwa Mansur Ali, SC Bang, SC Basak, Seng-Kai Ong, SF Liou, SM Capitosti, T Antonucci, T Ellendorff, T Ishikawa, TB Emran, TC Lima, TC Yang, TES Ali, TP Yin, TR Burke, TS Tiuman, TT Cushnie, TW Sanchez, U Guzzi, U Singh, V Bhardwaj, V Exarchou, V Facchinetti, V Mihailovic, V Miliukienė, VK Bajpai, VV Kouznetsov, VV Kouznetsov, W He, X He, XD Wang, XJ Gao, XN Wang, XP Sun, Y Dai, Y Fang, Y Girard, Y Take, Y Tang, Y Zhao, Y Özkay, YH Seo, YLN Murthy, YM Sinam, Z Su   +215 more
core   +1 more source

A Graphene Acid - TiO2 Nanohybrid as Multifunctional Heterogeneous Photocatalyst for the Synthesis of 1,3,4-Oxadiazoles [PDF]

, 2022
The immobilization of TiO2 nanoparticles on graphene acid (GA), a conductive graphene derivative densely functionalized with COOH groups, is presented.
Alemán Lara, José Julián, Barawi, Mariam, Blanco Fernández, Matías, De La Peña O. Shea, Víctor A., Navío, Cristina, Sciarretta, Martina   +5 more
core   +1 more source

Diazo Transfer From Nitrous Oxide Employing Phosphorus Ylides

Angewandte Chemie, EarlyView.
A phosphorus ylide‐mediated strategy achieves the direct fixation of nitrous oxide (N2O) to access diazo compounds, which after intra‐ or intermolecular trapping, afford N2‐containing organic building blocks. This approach provides an alternative to hazardous diazo‐transfer reagents and establishes N2O fixation as a sustainable methodology.
Jhen‐Kuei Yu, Jan Niclas Ludwig, Patrick Wolf Antoni, David Tymann, Max Martin Hansmann   +4 more
wiley   +2 more sources

Crystal structure of 2-(adamantan-1-yl)-5-(3,5-dinitrophenyl)-1,3,4-oxadiazole, C18H18N4O5 [PDF]

, 2022
C18H18N4O5, monoclinic, P21/c (no. 14), a = 11.7553(8) Å, b = 6.4876(4) Å, c = 22.3442(15) Å, β = 91.263(7)°, V = 1703.64(19) Å3, Z = 4, Rgt (F) = 0.0531, wRref (F 2) = 0.1376, T = 160 K.
Al-Wahaibi, Lamya H, Blacque, Olivier, El-Emam, Ali A, Tiekink, Edward R T   +3 more
core   +1 more source

Synthesis and Antimicrobial Studies of Some New 3-Isoxazoline Substituted Phthalazine Methylsulfonyl Oxadiazoles

E-Journal of Chemistry, 2011
A series of new 3-isoxazoline substituted phthalazine methylsulfonyl-oxadiazoles were prepared from methyl 2-(4-oxo-3,4-dihydrophthalazin-1-yl) acetate.
A. M. Sridhara, K. R. Venugopala Reddy, J. Keshavayya, D. S. Ambika, Sanathkumar Goud, S. K. Peethambar   +5 more
doaj   +1 more source

Synthesis, Reactions and Antioxidant Activity of 5-(3', 4'-dihydroxy-tetrahydrofuran-2'-yl)-2-methyl-3-carbohydrazide [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2019
In this manuscript, we describe the synthesis of the carbohydrazide 2. Acid-catalyzed condensation with several carbonyl compounds to afford the corresponding carbohydrazide derivatives 3-12.
Mohamed El Sadek, Samir Ahmed Magd, Seham Yassen Hassan, Mohamed A. Mostafa, Galile Yacouat   +4 more
doaj  

Synthesis and Reactions of Some New Heterocyclic Carbohydrazides and Related Compounds as Potential Anticancer Agents

Molecules, 2003
Acylation of 3-hydrazino-5,6-diphenyl-1,2,4-triazine (2) and hydrazine hydrate (7) with 4-aryl-1,3,7-triphenyl-8-oxa-1,2,6-triazaspiro[4.4]nona-2,6-dien-9-ones 5a,b gave the corresponding heterocyclic carbohydrazides 6a,b and 8a,b respectively ...
Nasser S. A. M. Khalil, Mohga M. Eid, Abdel Kader Mansour   +2 more
doaj   +1 more source