Results 31 to 40 of about 12,849,117 (223)
Synthesis and Antineoplastic Evaluation of Novel Unsymmetrical 1,3,4-Oxadiazoles
, 2016 A series of novel 1,3,4-oxadiazoles was synthesized and evaluated for their cytotoxic activity in in vitro tumor models. Four of the new compounds (2d, 2j, 2k, and 2n) showed growth inhibition in the XTT dye assay.
Giansalvo Pinna (3367052) +7 more
core +1 more source
SYNTHESIS AND BIOLOGICAL ACTIVITIES OF 1, 3, 4-OXADIAZOLE DERIVATIVES: A REVIEW OF LITERATURE. [PDF]
International Journal of Advanced Research, 2018 A series of derivatives of 1, 3, 4-oxadiazole having verities of biological activities can be synthesised by various methods. The activities include anticancer, antimicrobial, anti- inflammatory, anti- HIV, anti tubercular, anti diabetic, antifungal etc.
Baijika P +3 more
openaire +2 more sources
Molecules, 2003 Acylation of 3-hydrazino-5,6-diphenyl-1,2,4-triazine (2) and hydrazine hydrate (7) with 4-aryl-1,3,7-triphenyl-8-oxa-1,2,6-triazaspiro[4.4]nona-2,6-dien-9-ones 5a,b gave the corresponding heterocyclic carbohydrazides 6a,b and 8a,b respectively ...
Nasser S. A. M. Khalil +2 more
doaj +1 more source
Reaction of 2,5-Disubstituted-1,3,4-oxadiazoles [PDF]
, 1985 Some 5-aryl-2-mercapto-1,3,4-oxadiazole (I) reacted with maleic anhydride, maleic acid and p-benzoquinone affording 2-(5-aryl- -1,3,4-oxadiazol-2-ylthio)succinic anhydrides (II), 2-(5-aryl-1,3,4- -oxadiazol-2-ylthio)succinic acids (III) and 2-(2,5 ...
El-Barbary, Ahmed A. +1 more
core +1 more source
, 2022 Oxadiazoles are electron-poor, five-membered aromatic heterocycles that contain one oxygen and two nitrogen atoms [...
Antonio Palumbo Piccionello
core +1 more source
Synthesis a Number of Heterocyclic Compounds and some of chalcones Derived From Levofloxacin
Tikrit Journal of Pure Science, 2023 The hydrazide (1) was used as synthone for the following Compound pyridazine-3,6-dione (2) by reaction of hydrazide (1) with maleic anhydride and Compound phthalazine-1,4-dione (3) by the reaction of hydrazide (1) with phthalic anhydride.
Ekram Abdullah Basheer +2 more
doaj +1 more source
Angewandte Chemie, EarlyView.Die Click‐Chemie hat sich von dem Aufbau kovalenter Bindungen hin zum Spalten von Bindungen weiterentwickelt. Hier wird über einen Kaskaden‐Aufbau berichtet, der diese Verfahren kombiniert, um multifunktionale biomolekulare Gerüste in einer modularen Ein‐Topf‐Reaktion aufzubauen.
Markus Staudt +9 more
wiley +1 more source
SYNTHESIS AND CHARACTERIZATION OF [(5-MERCAPTO-1,3,4-OXADIAZOL-2-YL)ARYL]-3,5-DIARYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOTHIOAMIDES [PDF]
Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2011 The synthesis and characterization of [(5-mercapto-1,3,4-oxadiazol-2-yl)aryl]-3,5-diaryl-4,5-dihydro-1Hpyrazole-1-carbothioamides - derivatives of pyrazolines and 5-[4(3)-isothiocyanatophenyl]-2-thio-1,3,4-oxadiazoles were realized.
Zinaida Ribkovskaia +3 more
doaj
Angewandte Chemie International Edition, EarlyView.We introduce the Aza‐Büchner–Curtius–Schlotterbeck (ABCS) reaction: A mild, catalyst‐free method for homologating aryl imines. Diverging from the traditional BCS mechanism, the diazo intermediate undergoes selective C─C insertion to form an all‐carbon quaternary center.
Simon O. Angerer +6 more
wiley +1 more source
Oxidative Cyclization Protocol for the Preparation of Energetic 3‑Amino-5‑R‑1,2,4-oxadiazoles
, 2018 An efficient method has been developed for the synthesis of energetic 3-amino-5-R-1,2,4-oxadiazoles via iodobenzene diacetate (IBD)-mediated oxidative cyclization in high yields at ambient temperature.
Jean’ne M. Shreeve (1267290) +3 more
core +1 more source