Results 41 to 50 of about 12,849,117 (223)
E-Journal of Chemistry, 2012 A series of novel 3- methyl-7-substituted-4H,4-benzothiazine-2-carbohydrazide (3a-e) and corresponding thiosemicarbazides (4-a-q); 2-[3-methyl-7-substituted- 4H -1, 4-benzothiazine-2-yl]-N-(aryl) hydrazine carbothiamide have been synthesized.
Bhikan J Khairnar +6 more
doaj +1 more source
Acta Chimica Slovenica, 2017 A series of diethyl-2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate derivative coupled to 1,3,4-oxadiazole-5-thiones and 1,2,4-triazole-5-thiones moieties at C2,C6 positions of 1,4-dihydropyridine ring system was prepared.
Maghsoud Ziaie +2 more
doaj +1 more source
Pharmaceuticals, 2021 A current trend in the quest for new therapies for complex, multifactorial diseases, such as diabetes mellitus (DM), is to find dual or even multi-target inhibitors.
Ádám Sipos +8 more
doaj +1 more source
Angewandte Chemie International Edition, EarlyView.Click chemistry has evolved from making covalent connections to also breaking bonds. Here, a cascade assembly is reported that combines these maneuvers to build multifunctional biomolecular scaffolds in a modular one‐pot reaction. The unifying azide release‐tetrazine hub clicks with a trans‐cyclooctene tag, rapidly liberates N,N‐dimethylaniline to ...
Markus Staudt +9 more
wiley +1 more source
Oxadiazoles in Medicinal Chemistry
, 2016 Oxadiazoles are five-membered heteroaromatic rings containing two carbons, two nitrogens, and one oxygen atom, and they exist in different regioisomeric forms.
Eric Wellner (1589959) +4 more
core +2 more sources
2:1 Adducts Arising from Reactions between Benzynes and 1,3,4-Oxadiazoles
2:1 adducts arise from the reaction of 2,5-diaryl-1,3,4-oxadiazoles and benzynes generated from the hexadehydro-Diels–Alder (HDDA) reaction. Density functional theory computations support a mechanistic manifold that includes a concerted SNAr process ...
Paul V. Kevorkian (10522165) +2 more
core +2 more sources
C‐Terminal Functionalization Methods of Amino Acids, Peptides, and Proteins
Chemistry – A European Journal, EarlyView.C‐terminal functionalization offers powerful routes to peptide and protein diversification, yet epimerization, hydrolysis, and selectivity remain key challenges. This Review surveys enzymatic, decarboxylative, and condensation strategies, highlighting advances toward chemo‐ and regioselective, protecting‐group‐free, atom‐efficient methods applicable to
Jay Hanssens +3 more
wiley +1 more source
Reaktionen von 3-Dimethylamino-2,2-dimethyl-2H-azirin mit aromatischen Carbonsäurehydraziden
CHIMIA, 1978 Reaction of 3-dimethylamino-2,2-dimethyl-2H-azirine (1) with salicylic acid hydrazide (2c) in acetonitrile at room temperature gives the amidrazone 3c as a primary product in 78% yield. Cyclization of 3c in methanol leads to the 1,2,5,6-tetrahydro-1,2,4-
Stanislav Chaloupka, Heinz Heimgartner
doaj +1 more source
Molecules, 2022 Five series of heterocyclic tripartite 2,6-difluorobenzamides, namely 1,2,3-triazoles, 1,2,4- and 1,3,4-oxadiazoles, analogs of reported model anti-staphylococcal compounds, were prepared. The purpose was to investigate the influence of the nature of the
Thibaut Barbier +6 more
doaj +1 more source
Recent advances and prospects for high‐efficiency blue hot exciton organic light‐emitting diodes
FlexMat, EarlyView.Blue organic light‐emitting diodes (OLEDs) face great challenges in achieving the balance between color purity, device efficiency, and stability. Hot exciton materials offer a solution by rapidly converting non‐emissive triplet excitons into singlet ones through a high‐lying reverse intersystem crossing process.
Xiaoen Shi +3 more
wiley +1 more source