Results 31 to 40 of about 61,740 (193)
A Novel Alkaloid Isolated from (Rutaceae)
Natural Product Communications, 2016 A novel alkaloid 3-hydroxy-4-(2-hydroxyethyl)-4′-methoxy-7′ H -quinolino[2,1- b ]quinazolin-7′-one, named atlanticol ( 1 ), was isolated from Spiranthera atlantica (Rutaceae), along with five known compounds: lupeol ( 3 ), γ-fagarine ( 4 ), skimmianine (
Michelle Rodrigues e Rocha +3 more
doaj +1 more source
Novel approaches to the treatment of Pseudomonas aeruginosa infections in cystic fibrosis [PDF]
, 2012 Pseudomonas aeruginosa chronically infects patients with cystic fibrosis and is associated with greater morbidity. There has been limited progress on the clinical development of new antibiotics with novel modes of action.
Cámara, Miguel +2 more
core +2 more sources
mSphere, 2021 Bacteria and phytoplankton form close associations in the ocean that are driven by the exchange of chemical compounds. The bacterial signal 2-heptyl-4-quinolone (HHQ) slows phytoplankton growth; however, the mechanism responsible remains unknown.
Scott B. Pollara +9 more
doaj +1 more source
BMC Infectious Diseases, 2011 Background Antibiotic resistance has necessitated fluoroquinolone use but little is known about the selective forces and resistance trajectory in malaria-endemic settings, where selection from the antimalarial chloroquine for fluoroquinolone-resistant ...
Lamikanra Adebayo +6 more
doaj +1 more source
Scientific Reports, 2023 Flavonoids are plant-produced secondary metabolites that are found ubiquitously. We have previously reported that apigenin, a class of flavonoid, has unique antimicrobial activity against Staphylococcus aureus (S.
Yuh Morimoto +6 more
doaj +1 more source
1,2-Substituted 4-(1H)-Quinolones: Synthesis, Antimalarial and Antitrypanosomal Activities in Vitro
Molecules, 2014 A diverse array of 4-(1H)-quinolone derivatives bearing substituents at positions 1 and 2 were synthesized and evaluated for antiprotozoal activities against Plasmodium falciparum and Trypanosoma brucei rhodesiense, and cytotoxicity against L-6 cells in ...
Abraham Wube +6 more
doaj +1 more source
Quorum sensing: An imperative longevity weapon in bacteria [PDF]
, 2018 Bacterial cells exhibit a complex pattern of co-operative behaviour as shown by their capacity to communicate amongst each other. Quorum sensing (QS) is a generic term used for bacterial cell-to-cell communication which secures survival of its species ...
Lahiri, Chandrajit *, Pawar, Shrikant
core +1 more source
Gut Pathogens, 2020 Introduction Quinolone prophylaxis is recommended for patients with advanced cirrhosis at high risk of spontaneous bacterial peritonitis (SBP) or with prior SBP.
Marcus M. Mücke +8 more
doaj +1 more source
Biotic inactivation of the Pseudomonas aeruginosa quinolone signal molecule [PDF]
, 2015 In Pseudomonas aeruginosa, quorum sensing (QS) regulates the production of secondary metabolites, many of which are antimicrobials that impact on polymicrobial community composition.
Birmes, Franziska S. +9 more
core +2 more sources
Advanced Science, EarlyView.This study systematically compares the degradation efficiency of CIP in a H2O2‐alone system and a novel Bi12FeO20‐H2O2 photo‐Fenton system. It reveals for the first time the presence of a quinone‐imine intermediate in the H2O2‐alone system, which exhibits toxicity comparable to CIP.
Wenting Qiu +9 more
wiley +1 more source