Results 101 to 110 of about 34,010 (190)

Changes in the Dispensing of Antibiotics to Australian Children Between 2013 and 2023: Are We Heading in the Right Direction?

Paediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Antimicrobial resistance (AMR) poses a critical public health issue, exacerbated by the overuse and misuse of antibiotics. Children are particularly susceptible to bacterial infections and are frequently prescribed antibiotics. Objective This study examined trends in antibiotic dispensing to children aged under 13 years in Australia
Erin Kelty, Ella Tairy, Scott Sims, Carol Orr, Amy Page, David B. Preen, Frank M. Sanfilippo, Christopher Etherton‐Beer, Ebony Quintrell   +8 more
wiley   +1 more source

Synthesis and Antibacterial Evaluation of a New Series of <em>N</em>-Alkyl-2-alkynyl/(<em>E</em>)-alkenyl-4-(1<em>H</em>)-quinolones

Molecules, 2012
To gain further insight into the structural requirements of the aliphatic group at position 2 for their antimycobacterial activity, some <em>N</em>-alkyl-4-(1<em>H</em>)-quinolones bearing position 2 alkynyls with various chain ...
Abraham Wube, Juan-David Guzman, Antje Hüfner, Christina Hochfellner, Martina Blunder, Rudolf Bauer, Simon Gibbons, Sanjib Bhakta, Franz Bucar   +8 more
doaj   +1 more source

Design, Synthesis, SAR, Pharmacokinetic Prediction of New 4-Quinolones as Anti-Microbial Agents. [PDF]

Russ J Gen Chem, 2022
Dubal GG, Vachchharajani PR, Solanki MJ, Shah VH.   +3 more
europepmc   +1 more source

Combination Therapy with Ciprofloxacin plus Azlocillin against Pseudomonas aeruginosa: Effect of Simultaneous versus Staggered Administration in an In Vitro Model of Infection [PDF]

, 2017
The effect of dose scheduling on the pharmacodynamics of simulated human doses of ciprofloxacin (200 mg intravenously [iv] every 12 h) and azlocillin (4 g iv every 12 h) alone or in combination against Pseudomonas aeruginosa was studied in a two ...
Blaser, Juerg, Dudley, Michael N., Gilbert, Deborah, Mayer, Kenneth H., Zinner, Stephen H.   +4 more
core  

Azlocillin can be the potential drug candidate against drug-tolerant Borrelia burgdorferi sensu stricto JLB31. [PDF]

, 2020
Lyme disease is one of most common vector-borne diseases, reporting more than 300,000 cases annually in the United States. Treating Lyme disease during its initial stages with traditional tetracycline antibiotics is effective. However, 10-20% of patients
Ahmed, Mohamed Sohail, Ambati, Aditya, Inayathullah, Mohammed, Mallajosyula, Venkata Vamsee Aditya, Pothineni, Venkata Raveendra, Potula, Hari-Hara SK, Rajadas, Jayakumar, Sridharan, Brindha   +7 more
core  

Studies of overcoming acquired resistance : molecular mechanisms and development of novel drugs [PDF]

, 2014
Chemotherapeutic agents have become widely applied for treatment of various types of malignancies. Drug resistance unfortunately remains as a major obstacle for the effectiveness of chemotherapy.
Wang, Xin
core   +1 more source

Triple Matrix Confinement‐Induced Ultrabright Afterglow From Carbon Dots With Multivariate Responsive Afterglow Colors for Advanced Dynamic Information Encryption

Angewandte Chemie, Volume 138, Issue 16, 13 April 2026.
A novel carbon dots material (BUL‐CDs) with an initial afterglow brightness (406 cd m−2) far exceeding that of other afterglow luminescent materials was developed. Furthermore, the BUL‐CDs exhibited time‐dependent afterglow colors, excitation‐dependent afterglow colors, and thermochromic afterglow in response to triplet variables.
Yupeng Liu, Yiming Hao, Yi Li, Xiaofan Xia, Xichang Ou, Xue Wu, Jun Wu, Ruifeng Zheng, Dongbo Guo, Shi Chen, Jing Li, Jinyang Zhu, Qijun Li, Songnan Qu   +13 more
wiley   +2 more sources

Two new 2-alkylquinolones, inhibitory to the fish skin ulcer pathogen Tenacibaculum maritimum, produced by a rhizobacterium of the genus Burkholderia sp.

Beilstein Journal of Organic Chemistry, 2018
Exploration of rhizobacteria of the genus Burkholderia as an under-tapped resource of bioactive molecules resulted in the isolation of two new antimicrobial 2-alkyl-4-quinolones.
Dandan Li, Naoya Oku, Atsumi Hasada, Masafumi Shimizu, Yasuhiro Igarashi   +4 more
doaj   +1 more source

Identification of 5-(Aryl/Heteroaryl)amino-4-quinolones as Potent Membrane-Disrupting Agents to Combat Antibiotic-Resistant Gram-Positive Bacteria. [PDF]

J Med Chem, 2022
Schultz JR, Costa SK, Jachak GR, Hegde P, Zimmerman M, Pan Y, Josten M, Ejeh C, Hammerstad T, Sahl HG, Pereira PM, Pinho MG, Dartois V, Cheung A, Aldrich CC.   +14 more
europepmc   +1 more source

Foodborne Carcinogens: Formation Pathways, Health Risks, and Cutting‐Edge Physical and Chemical Prevention Strategies

eFood, Volume 7, Issue 3, June 2026.
This review highlights the formation of foodborne carcinogens during processing and evaluates different mitigation strategies, including natural antioxidants and modern cooking techniques, to reduce associated cancer risks and enhance food safety. ABSTRACT Food processing methods, though vital for improving food safety, taste, and shelf life, can ...
Naglaa S. Ashmawy, Ahmed A. Zaky, Noha H. Badr, Ali Korin, Mohamed A. Farag   +4 more
wiley   +1 more source