Results 131 to 140 of about 34,010 (190)

Copper‐ and Silver‐Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five‐ and Six‐Membered Heterocycles

Chemistry – A European Journal, Volume 32, Issue 13, 1 April 2026.
This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
Jimil George, Kyungsoo Oh
wiley   +1 more source

Clinical Outcome Associated With Beta‐Lactam Allergy Labels in Hospitalized Patients in Belgium

Clinical and Translational Allergy, Volume 16, Issue 4, April 2026.
ABSTRACT Background In the United States, beta‐lactam allergy labels (BLAL) are documented in 9%–16% of hospitalized patients and associated with worse clinical outcomes such as increased mortality, length of hospital stay (LOS), intensive care unit (ICU) admission, and use of alternative antibiotics, providing an incentive for broad delabeling ...
Liesbeth Gilissen, Greet Van De Sijpe, Annouschka Laenen, Peter Declercq, Dries Wets, Ileana Ghiordanescu, Anca Mirela Chiriac, Willy E. Peetermans, Paul De Munter, Isabel Spriet, Rik Schrijvers   +10 more
wiley   +1 more source

Diagnosis and treatment of gastric abscess by endoscopic ultrasound: A mini‐review of the preliminary application

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Gastric abscess is a rare condition caused by gastric barrier damage. It is easily misdiagnosed in clinical practice as a cancer recurrence or submucosal tumor, especially after surgery or endoscopic submucosal dissection. With a relatively high mortality rate, the cause and clinical characteristics of gastric abscesses are obscure.
Jia Xie, Mo‐Jin Wang, Rui Wang
wiley   +1 more source

Pallado-Catalyzed Cascade Synthesis of 2-Alkoxyquinolines from 1,3-Butadiynamides

Molecules
A novel synthesis strategy to access 2-alkoxyquinoline derivatives via a palladium-driven cascade reaction is disclosed. Unlike classic methods based on the alkylation of 2-quinolones with alkyl halides, the present method benefits from the de novo ...
Illia Lenko, Alexander Mamontov, Carole Alayrac, Bernhard Witulski   +3 more
doaj   +1 more source

Antimicrobial‐Resistance Genetic Markers Among Multidrug‐Resistant Enterobacteriaceae and Acinetobacter spp. From Vegetable Market Chains in Ethiopia

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Schematic overview of the study workflow explaining isolation of lactose‐fermenting Gram‐negative bacteria from farms and supermarkets, antimicrobial susceptibility testing, detection of resistance genes by PCR, and ERIC‐PCR to evaluate genetic diversity and relatedness among isolates.
Hemen Tesfaye, Adey Feleke Desta, Ahu Reis, Mine Egin, Osman Birol Ozgumus, Neslihan Akarsu, Mujib Abdulkadir, Haile Alemayehu, Tadesse Eguale, Ali Osman Kilic   +9 more
wiley   +1 more source

Preclinical efficacy of tasquinimod in myelodysplastic neoplasms: Restoring erythropoiesis and mitigating bone loss

HemaSphere, Volume 10, Issue 4, April 2026.
Abstract Myelodysplastic neoplasms (MDSs) are clonal disorders characterized by ineffective hematopoiesis, dysplasia, and a risk of transformation into acute myeloid leukemia. MDS is also associated with a higher incidence of osteoporosis, suggesting a complex interplay between hematopoiesis, the bone marrow (BM) microenvironment, and bone homeostasis.
Manja Wobus, Heike Weidner, Rebekka Wehner, Anna‐Lena Baumann, Kristin Möbus, Ekaterina Balaian, Marie Törngren, Erik Vahtola, Helena Eriksson, Susann Winter, Uwe Platzbecker, Triantafyllos Chavakis, Lorenz Christian Hofbauer, Martina Rauner, Martin Bornhäuser, Katja Sockel   +15 more
wiley   +1 more source

Isolation of Extracellular Vesicles From Gram‐Negative Bacteria: A Solid Medium‐Based Method Analysis

Journal of Extracellular Biology, Volume 5, Issue 4, April 2026.
ABSTRACT Extracellular vesicles (EVs) produced by gram‐negative bacteria have gained increased scientific interest over the last years due to a growing understanding of their roles in pathogenesis and biotechnological potential. However, isolating such nanoparticles is technically challenging. Here, we evaluated a rapid and reproducible protocol for EV
Roberto G. M. Guardatti, Jhonatha R. Cordeiro‐Moura, Jhon J. Artunduaga Bonilla, Stefanie C. da Costa, Anderson S. Cabral, Bruna Montalvão, Flávia G. C. Reis, Leonardo Nimrichter, Márcio L. Rodrigues, Juliana Rizzo, Renata C. Picão   +10 more
wiley   +1 more source

Emerging Antimicrobial Resistance in Klebsiella pneumoniae: A Molecular and Antibiogram Insight From the Beef Value Chain in Bangladesh

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
A total of 132 Multidrug‐resistant Klebsiella pneumoniae was detected across the beef value chain in Bangladesh, including slaughterhouses, wet markets, and ready‐to‐eat beef outlets. Upon cultural traits, PCR, 16S rRNA sequencing, antibiogram analysis, and ARG detection revealed carbapenem resistance genes (blaIMP and blaBIC), highlighting foodborne ...
Md Sodor Uddin, Fahmida Jahan Fahim, Sohel Rana, Abdullah Al Kafi, Jobaida Khanam, Md Nazim Uddin, Md Masudur Rahman, Monira Noor, Md Mukter Hossain, Md Mahfujur Rahman, Md Bashir Uddin, Ferdaus Mohd Altaf Hossain   +11 more
wiley   +1 more source

Nasal Carriage Rate of Biofilm Producing Methicillin Resistant Staphylococcus aureus and Its Associated Factors Among Health Care Workers at Hospital of Central Ethiopia

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
ABSTRACT Not susceptible to methicillin Staphylococcus aureus (MRSA), is a potentially harmful bacteria that is resistant to the most important antimicrobial agents. Because MRSA is so resistant to many antibiotics, it can cause illnesses by forming biofilms.
Wubeshet Mathewos, Abera Kumalo, Takele Teklu, Tigistu Demisse, Muluneh Temesgen, Tariku Chinasho   +5 more
wiley   +1 more source

Imported Retail Beef and Chicken Meat Products Serve as Reservoirs for Emerging Antibiotic‐Resistant Pathotypes of Escherichia coli in Pristine Areas Free From Agricultural Activity

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
Retail meat–derived E. coli frequently harbored multidrug‑resistance phenotypes, diverse virulence determinants, and plasmid‑encoded resistance genes with high conjugative potential. Results indicate meat and poultry as underrecognized reservoirs facilitating dissemination of antimicrobial resistance and pathogenic lineages, with imported products ...
Saehah Yi, Kathleen A. Alexander, Auja Bywater, Galaletsang Dintwe, Ashton N. Sies, Thomas H. Haidl, Andrew D. S. Cameron, Monica A. Ponder   +7 more
wiley   +1 more source