NOVEL HETEROCYCLES BASED ON 1, 3, 4-THIADIAZOLE SCAFFOLD AS INSECTICIDES [PDF]
Journal of Environmental Science, 2017 The crop plants are the major source of human nutrition, but insects and pests cause huge economic losses every year. The authors were interested in developing novel insecticidal agents with low toxicity and an acceptable impact on the environment. Thus, 2-amino-5-(substituted)-1, 3, 4-thiadiazoles (1a, b) were used as versatile materials to synthesize
Madkour, H. F +3 more
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2-(4-Fluorophenyl)-3-[5-(4-nitrophenyl)-1,3,4-thiadiazol-2-yl]-1,3-thiazolidin-4-one
Acta Crystallographica Section E, 2010 In the title compound, C17H11FN4O3S2, the five-membered thiazolidinone and thiadiazole rings are almost planar, with r.m.s. deviations of 0.017 and 0.0019 Å, respectively.
Peng Yu +4 more
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N-(5-Benzylsulfanyl-1,3,4-thiadiazol-2-yl)-2-(piperidin-1-yl)acetamide
Acta Crystallographica Section E, 2014 The title compound, C16H20N4OS2, was synthesized by the reaction of 2-benzylsulfanyl-5-chloroacetamido-1,3,4-thiadiazole and piperidine in a 1:2 ratio. The planes of the acetamide and 1,3,4-thiadiazole units are twisted by 10.8 (4)°.
D. S. Ismailova +4 more
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Synthesis and crystal structure analysis of 2-(4-fluorobenzyl)-6-phenylimidazo[2,1-b]- [1,3,4]thiadiazole and its chlorophenyl derivative [PDF]
, 2014 Prepns. of 2-(4-fluorobenzyl)-6-phenylimidazo[2,1-b][1,3,4]thiadiazole and its chlorophenyl deriv. were described. Preliminary anal. was done spectroscopically by means of 1H NMR, 13C NMR spectra, mass spectra and elemental analyses. Further
Afshan Banu, . +3 more
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Synthesis and Preliminary Antimicrobial Study of 2-Amino-5-Mercapto-1,3,4-Thiadiazole Derivatives
Iraqi Journal of Pharmaceutical Sciences, 2017 Nitrogen heterocycles are of a special interest because they constitute an important class of natural and non natural products, many of which exhibit useful biological activities.Among these nitrogen heterocycles are 1, 3, 4-thiadiazole containing ...
Husam A. Ameen, Ahlam J. Qasir
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Molecules, 2015 A number of novel heterocyclic chalcone derivatives can be synthesized by thermal and microwave tools. Treatment of 4-(4-Acetylamino- and/or 4-bromo-phenyl)-4-oxobut-2-enoic acids with hydrogen peroxide in alkaline medium were afforded oxirane ...
Maher A. El-Hashash +2 more
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Synthesis of new thiophene derivatives and their use as photostabilizers for rigid poly(vinyl chloride) [PDF]
, 2015 Five new thiophenes, namely, N-[(3-bromo-2-methylthiophen-5-yl)methylene]-4-methoxyaniline (4a), N-[(3-bromo-2-methylthiophen-5-yl)methylene]-3,4-dimethoxyaniline (4b), N-[(3-bromo-2-methylthiophen-5-yl)methylene]-3,4-dimethylaniline (4c), 3-[(3-bromo-2 ...
Ahmed, Ahmed +4 more
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5-({3-[(5-Amino-1,3,4-thiadiazol-2-yl)sulfanylmethyl]benzyl}sulfanyl)-1,3,4-thiadiazol-2-amine
Acta Crystallographica Section E, 2012 In the title compound, C12H12N6S4, the two terminal thiadiazole rings are twisted with respect to the central benzene ring, making dihedral angles of 54.28 (4) and 76.56 (3)°.
Sung Kwon Kang +2 more
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Unusual anti-leukemia activity of nanoformulated naproxen and other non-steroidal anti-inflammatory drugs [PDF]
, 2016 The non-steroidal anti-inflammatory drugs (NSAIDs) are the most widely used pharmaceuticals worldwide. Interestingly, many of them have significant anticancer properties too.
Aboul-Fadl +76 more
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Synthesis and Antiviral Activity of 5‑(4‑Chlorophenyl)-1,3,4-Thiadiazole Sulfonamides
Molecules, 2010 Starting from 4-chlorobenzoic acid, 10 new 5-(4-chlorophenyl)-N-substituted-N-1,3,4-thiadiazole-2-sulfonamide derivatives were synthesized in six-steps. Esterification of 4-chlorobenzoic acid with methanol and subsequent hydrazination, salt formation and
Yuping Zhang +7 more
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