Results 11 to 20 of about 11,436,166 (282)

Novel 1, 2, 4‐Triazoles as Antifungal Agents

open access: yesBioMed Research International, 2022
The development of innovative antifungal agents is essential. Some fungicidal agents are no longer effective due to resistance development, various side effects, and high toxicity. Therefore, the synthesis and development of some new antifungal agents are necessary. 1,2,4‐Triazole is one of the most essential pharmacophore systems between five‐membered
Zahra Kazeminejad   +5 more
openaire   +2 more sources

Insights into Corrosion Inhibition Behavior of a 5-Mercapto-1, 2, 4-Triazole Derivative for Mild Steel in Hydrochloric Acid Solution: Experimental and DFT Studies

open access: yesLubricants, 2021
A triazole heterocyclic compound namely 3-(4-ethyl-5-mercapto-1, 2, 4-triazol-3-yl)-1-phenylpropanone (EMTP) was examined for its corrosion protection of mild steel (MS) against 1 M hydrochloric acid medium using gravimetric techniques.
Israa Abd Alkadir Aziz   +8 more
semanticscholar   +1 more source

The synthesis of 4-amino-5-(quinolin-2-yl)-4H-1,2,4-triazole-3-thiol and its interaction with aldehydes

open access: yesЖурнал органічної та фармацевтичної хімії, 2021
Aim. To synthesize 4-amino-5-(quinolin-2-yl)-4H-1,2,4-triazole-3-thiol and study its reactivity in the reaction with aldehydes. Results and discussion.
D. М. Zozulynets   +2 more
doaj   +1 more source

Synthesis and Ring-Chain Tautomerism of 1-(4-Ethoxyphenyl)-5-formyl-1H-1,2,3-triazole-4-carboxylic Acid: The First Representative of a 5-Formyl-1H-1,2,3-triazole-4-carboxylic Acids Series

open access: yesMolbank, 2022
Synthesis of the first representative of a 5-formyl-1H-1,2,3-triazole-4-carboxylic acids series – 1-(4-ethoxyphenyl)-5-formyl-1H-1,2,3-triazole-4-carboxylic acid was performed.
Nazariy T. Pokhodylo, Mykola D. Obushak
doaj   +1 more source

Synthesis and Characterization of the Triazole Derived from Thiosemicarbazide, 4-Amino-5-Phenyl-4H-1,2,4- Triazole-3-Thiol and Their Copper(II) and Nickel(II) Complexes [PDF]

open access: yesEngineering and Technology Journal, 2013
Triazole N-(3-mercapto-5-phenyl-4H-1,2,4-triazol-4-yl)hydrazinecarbothioamide prepared in good yield via the condensation of 4-amino-5-phenyl-4H-1,2,4-triazole-3-thiol and thiosemicarbazide.
Hamdan Abood Aday
doaj   +1 more source

Corrosion mitigation of carbon steel using triazole Mannich base derivatives: Correlation of electrochemical studies with quantum chemical calculations

open access: yesArab Journal of Basic and Applied Sciences, 2023
The study investigated the corrosion-inhibitory properties of three synthetic triazole Mannich bases on C1018 carbon steel using various electrochemical techniques.
N. Phadke Swathi   +7 more
doaj   +1 more source

Preparation and antitumor effects of 4-amino-1,2,4-triazole Schiff base derivative

open access: yesJournal of International Medical Research, 2020
Objectives The purpose of this paper was to synthesize 4-amino-1,2,4-triazole Schiff base derivative and to evaluate its antitumor activity. Methods 2,4,6-Tris (4-formylphenoxy)-1,3,5-triazine was synthesized by nucleophilic substitution with reaction of
Guo-wei Jiang   +5 more
doaj   +1 more source

Antimicrobial and antifungal activity of new fluorophenyl-containing 1,2,4-triazoles

open access: yesФармацевтичний журнал, 2021
The achievements of the world organic chemistry are most clearly represented by scientific publications that prove the promising nature of heterocyclic substances.
O. A. Bihdan
doaj   +1 more source

1-(4-Nitrophenyl)-1H-1,2,3-Triazole-4-carbaldehyde: Scalable Synthesis and Its Use in the Preparation of 1-Alkyl-4-Formyl-1,2,3-triazoles

open access: yesOrganics, 2021
1,2,3-Triazole-4-carbaldehydes are useful synthetic intermediates which may play an important role in the discovery of novel applications of the 1,2,3-triazole moiety.
Tomas Opsomer   +3 more
doaj   +1 more source

Discovery of a Potent α ‑ Galactosidase Inhibitor by in Situ Analysis of a Library of Pyrrolizidine − (Thio)urea Hybrid Molecules Generated via Click Chemistry [PDF]

open access: yes, 2018
The parallel synthesis of a 26-membered-library of aromatic/aliphatic-(thio)urea-linked pyrrolizidines followed by in situ biological evaluation toward α -galactosidases has been carried out.
Carmona Asenjo, Ana Teresa   +8 more
core   +1 more source

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