Discovery of a Potent α ‑ Galactosidase Inhibitor by in Situ Analysis of a Library of Pyrrolizidine − (Thio)urea Hybrid Molecules Generated via Click Chemistry [PDF]
, 2018 The parallel synthesis of a 26-membered-library of aromatic/aliphatic-(thio)urea-linked pyrrolizidines followed by in situ biological evaluation toward α -galactosidases has been carried out.
Carmona Asenjo, Ana Teresa +8 more
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The search for new 4-amino-5-methyl-4H-1,2,4-triasole-3-thion derivatives with diuretic activity
Zaporožskij Medicinskij Žurnal, 2018 1,2,4-Triazole derivatives have been widely used in medical practice due to their wide spectrum of biological activities and low toxicity, as they have 1,2,4-triazole cycle in their structure.
T. V. Kravchenko
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Molbank, 2022 Synthesis of the first representative of a 5-formyl-1H-1,2,3-triazole-4-carboxylic acids series – 1-(4-ethoxyphenyl)-5-formyl-1H-1,2,3-triazole-4-carboxylic acid was performed.
Nazariy T. Pokhodylo, Mykola D. Obushak
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016 Aim. To study the effect of 4-benzylideneamino-5-phenyl-4H-1,2,4-triazole-3-thiones and salts of 2-(4-amino-5-phenyl-4H-1,2,4-triazole-3-yltio)acetic acid on central component of nociceptive system on condition of thermal stimulation of limbs of rats ...
Ye. S. Pruhlo
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Study acute toxicity of 4-(R-amino)-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol in vivo
Фармацевтичний журнал, 2018 Typically, the system is already known are used as the core for a new substance, which have already proved themselves as potential drugs. So one of these is 1,2,4-triazole ring.
A. A. Safonov
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Arab Journal of Basic and Applied Sciences, 2023 The study investigated the corrosion-inhibitory properties of three synthetic triazole Mannich bases on C1018 carbon steel using various electrochemical techniques.
N. Phadke Swathi +7 more
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Synthesis of [(1,2,3-Triazol-1-yl)methyl]boronic Acids Through Click Chemistry: Easy Access to a Potential Scaffold for Protease Inhibitors [PDF]
, 2015 Stereoselective synthesis of previously unreported [(1,2,3-triazol-1-yl)methyl]boronic acids has been achieved from azidomethylboronates by copper-catalyzed azide–alkyne cycloaddition reaction.
CASELLI, Emilia +2 more
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Chemical investigation of light induced DNA bipyrimidine damage and repair [PDF]
, 2011 In all organisms, genetic information is stored in DNA and RNA. Both of these macromolecules are damaged by many exogenous and endogenous events, with UV irradiation being one of the major sources of damage.
Carell, Thomas +2 more
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Unraveling the dynamics of protein-protein interactions in the Gcn2 signal transduction pathway : a thesis presented in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Microbiology and Genetics, Massey University, Albany, New Zealand [PDF]
, 2016 Content removed from Publications section due to copyright reasons: Cridge, A. G., Viswewaraiah, J., Ramesh, R., & Sattlegger, E. (2014). Semi-quantitative colony immunoassay for determining and optimizing protein expression in Saccharomyces cerevisiae
Ramesh, Rashmi
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Фармацевтичний журнал, 2018 The large interest in the plan of search biologically of active agents is caused by the heterocyclic system of 1,2,4-triazole, due to high biological activity, and by the low indexes of toxicness, that inherent it to the structural analogues.
Т. М. Kaplaushenko +2 more
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