Results 51 to 60 of about 11,698,793 (281)

Analgesic Activity of Some 1,2,4-Triazole Heterocycles Clubbed with Pyrazole, Tetrazole, Isoxazole and Pyrimidine [PDF]

, 2013
Purpose: In the present study in vivo analgesic activity of some previously synthesized 1,2,4-triazole derivatives containing pyrazole, tetrazole, isoxazole and pyrimidine ring have been evaluated.
Appala Raju, Popat Baban Mohite, Ramdas Bhanudas Pandhare, Shantaram Gajanan Khanage   +3 more
core   +1 more source

Efficacy of botanicals and fungicides against Rhizoctonia solani inciting sheath blight disease on Rice (Oryza sativa L.) [PDF]

, 2017
Among the fungal diseases, sheath blight, caused by multinucleate Rhizoctoniasolani Kuhn (teleomorph: Thanatephorus cucumeris Donk), a ubiquitous pathogen, is an important fungal disease of rice ranking only after blast and often rivalling it.
Chaudhary, Sorabh, Chaudhary, V.P., Kumar, Ajay, Kumar, Dharmendra, Kumar, Vipin, Sagar, Sushma   +5 more
core   +2 more sources

Synthesis, structure and properties of N-R-amides and hydrazides of 2-[4-R-5-(theophylline-7ʹ-yl)-1,2,4-triazole-3-ylthio]acetic acid

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
One of the most important tasks of modern pharmaceutical science is the search for new biologically active substances, which have high efficacy and low toxicity.
A. S. Gotsulya
doaj   +1 more source

Syntheses of Some 3,5-Diaryl-4H-1,2,4-triazole Derivatives and their Antifungal Activity

E-Journal of Chemistry, 2009
Syntheses of a series of 3, 5-diaryl-4H-1, 2, 4-triazole derivatives are described. In this present work, 4-amino-3-phenyl-5-p-tolyl-4H-1,2,4-triazole(1) was converted to N,N’-bis[3-phenyl-5-p-tolyl-4H-1,2,4-triazolyl]-1,4-xylenediimine(2) and 3-Phenyl-5-
Ram Janam Singh, Dharmendra Kumar Singh
doaj   +1 more source

Acute toxicity of 5-(furan-2-yl, 2-metylfuran-3-yl)-4-amino-1,2,4-triazole-3-thiol alkyl derivatives

Zaporožskij Medicinskij Žurnal, 2017
The purpose of our work was the further exploration of the new 5-(furan-2-yl, 2-metylfuran-3-yl)-4-amino-1,2,4-triazole-3-thiol alkyl derivatives’ acute toxicity, setting some patterns of alkyl substituents influence by the Sulfur atom on the acute ...
D. M. Danilchenko, V. V. Parchenko
doaj   +1 more source

1-(4-Nitrophenyl)-1H-1,2,3-Triazole-4-carbaldehyde: Scalable Synthesis and Its Use in the Preparation of 1-Alkyl-4-Formyl-1,2,3-triazoles

Organics, 2021
1,2,3-Triazole-4-carbaldehydes are useful synthetic intermediates which may play an important role in the discovery of novel applications of the 1,2,3-triazole moiety.
Tomas Opsomer, Kaat Valkeneers, Ana Ratković, Wim Dehaen   +3 more
doaj   +1 more source

Therapeutic effect of nucleoside analogs on experimental autoimmune encephalomyelitis in dark agouti rats [PDF]

, 2006
Experimental autoimmune encephalomyelitis (EAE) is a commonly used animal model of the human neurological disorder multiple sclerosis. The purpose of the present study was to investigate the effect of combined treatment with two nucleoside analogs ...
Bjelobaba Ivana, Gađanski Ivana, Lavrnja Irena, Mostarica-Stojković Marija, Peković Sanja, Rakić Lj., Stojiljković Mirjana, Stojkov Danijela, Stošić-Grujičić Stanislava, Šubašić Sanja   +9 more
core   +1 more source

Evaluation Of Antioxidant Activity Of 1, 2, 4-Triazole Derivatives With Morpholine Moiety

Hacettepe University Journal of the Faculty of Pharmacy, 2022
The aim of the work was to study the antioxidant activity of 4-R-3- (morpholinomethyl)-4H-1,2,4-triazole-5-thioles and their alkyl derivatives in vitro using the method of non-enzymatic initiation of lipid peroxidation. Among the 45 compounds studied, 8 showed varying degrees of AOA.
SHCHERBYNA, Roman, PRUHLO, Yevhen, DUCHENKO, Maryna, KULAGİNA, Mariia, KUDRİA, Victoriia, VALENTYNA, Vashchuk   +5 more
openaire   +2 more sources

SÍNTESE E AVALIAÇÃO DA ATIVIDADE CITOTÓXICA DE DERIVADOS DO EUGENOL CONTENDO NÚCLEOS 1,2,3-TRIAZÓLICOS

Química Nova
Eugenol is an aromatic compound found in several plant species. It presents important biological activities including cytotoxicity. In this paper, it is described the synthesis and the evaluation of the cytotoxic activity of eugenol derivatives bearing 1,
Poliana Aparecida Rodrigues Gazolla, Róbson Ricardo Teixeira, Adalberto Manoel da Silva, Boniek Gontijo Vaz, Géssica Adriana Vasconcelos, Raoni Pais Siqueira, Victor Hugo Sousa Gonçalves, Higor Sette Pereira, Gustavo Costa Bressan   +8 more
doaj   +1 more source

Neuroserpin polymers cause oxidative stress in a neuronal model of the dementia FENIB [PDF]

, 2017
The serpinopathies are human pathologies caused by mutations that promote polymerisation and intracellular deposition of proteins of the serpin superfamily, leading to a poorly understood cell toxicity.
Cacci, Emanuele, Carucci, Nicoletta, D'Acunto, Emanuela, DE JACO, Antonella, Guadagno, NOEMI ANTONELLA, Licursi, Valerio, Lupo, Giuseppe, MIRANDA BANOS, MARIA ELENA, Moriconi, Claudia, Negri, Rodolfo, Nisi, PAOLA SERENA   +10 more
core   +1 more source