Results 161 to 170 of about 18,771 (284)

Crystal structure of 4-ethyl-5-{[(4-methyl-4H-1,2,4-triazol-3-yl)- sulfanyl]methyl}-4H-1,2,4-triazole-3(2H)-thione, C8H12N6S2, the orthorhombic modification [PDF]

, 2006
Liliana Mazur, A.E. Kozioł, A. Maliszewska-Guz, Monika Wujec, Monika Pitucha, M. Dobosz   +5 more
openalex   +1 more source

Improved C5‐Amide Bioisosteres for Human Neuraminidase 1 Inhibitors Based on 2‐Deoxy‐2,3‐Didehydro‐N‐Acetyl Neuraminic Acid

ChemMedChem, EarlyView.
This article describes the development of improved NEU1 inhibitors based on the 2‐deoxy‐2,3‐didehydro‐N‐acetyl neuraminic acid scaffold. A series of candidate inhibitors are designed containing bioisosteres of the C5‐amide group and evaluated for activity against NEU1‐4 enzymes.
Mostafa Radwan, Elisa G. Carvajal, Christopher W. Cairo   +2 more
wiley   +1 more source

Novel, nanomagnetic and recoverable copper(0)-catalyst in one-pot access to 1,4-disubstituted 1,2,3-triazoles and 5-substituted 1H-tetrazoles in water. [PDF]

R Soc Open Sci
Amiri M, Bagherzadeh N, Sardarian AR.
europepmc   +1 more source

Triazole- and azo-coupled calix[4]arene as a highly sensitive chromogenic sensor for Ca2+ and Pb2+ ions [PDF]

, 2007
Kai‐Chi Chang, In-Hao Su, Gene‐Hsiang Lee, Wen‐Sheng Chung   +3 more
openalex   +1 more source

Deferasirox Derivatives as Inhibitors of Kallikrein‐Related Peptidases Associated to Neurodegenerative Diseases

ChemMedChem, EarlyView.
Dysregulated proteolysis mediated by kallikrein‐related peptidases (KLKs) and iron overload are involved in the progression of neurodegenerative diseases. Deferasirox, an clinically‐approved iron chelator, and its newly synthesized derivatives have been identified as inhibitors of major central nervous system KLKs with low cytotoxicity and effective ...
Rilès Boumali, Elodie David, Nancy Chaaya, Morane Lucas, Sabrina Aït Amiri, Valérie Lefort, Anthony Nina‐Diogo, Michèle Salmain, Isabelle Petropoulos, Vincent Corcé, Chahrazade El Amri, Candice Botuha   +11 more
wiley   +1 more source

3-Thio-3,4,5-trisubstituted-1,2,4-triazoles: high affinity somatostatin receptor-4 agonist synthesis and structure-activity relationships. [PDF]

RSC Med Chem
Crider AM, Hospital A, Sandoval KE, Neumann WL, Kukielski S, Garic L, Ingold K, Dunahoo M, Srabony KN, Frare R, Slater O, Peel N, Kontoyianni M, Witt KA.   +13 more
europepmc   +1 more source

Facile bromination of the benzene ring during the cyclisation of the 1H-3-methyl-4-ethoxycarbonyl-5-arylidenehydrazonopyrazoles to the 3-substituted-aryl-1H-6-methyl-7-ethoxycarbonyl--pyrazolo[3,2-c]-s-triazoles

, 2002
Carol Csunderlik, Vasile Bercean, Fráncisc Péter, Valentin Badea   +3 more
openalex   +2 more sources

35Cl NMR of Metal‐Organic Frameworks: What Can We Learn?

Chemistry–Methods, EarlyView.
35Cl solid‐state NMR of MOFs offers insights into bonding mode and character, hydrogen bonding, phase transitions, and reaction products, even near paramagnetic centers. 35Cl NMR parameters reflect Cl coordination and local geometry. DFT methods accurately predict 35Cl NMR parameters. This 35Cl NMR/DFT approach is applicable to other MOFs and materials.
Wanli Zhang, Bryan E. G. Lucier, Mathew J. Willans, Yining Huang   +3 more
wiley   +1 more source

Introduction and characterization of a novel Cu(ii)-based quaternary deep eutectic solvent and its application in the efficient synthesis of triazoles and tetrazoles under mild conditions as an inexpensive, reusable, benign, and dual solvent/catalyst medium. [PDF]

RSC Adv
Golestanifar L, Sardarian AR.
europepmc   +1 more source

Low‐Micromolar Quantification of Fluorinated Analytes Using Hyperpolarized 19F Benchtop Nuclear Magnetic Resonance

Chemistry–Methods, EarlyView.
Limits of detection and quantification of fluorinated analytes by 19F benchtop (1 T) NMR spectroscopy in the high nanomolar to low micromolar range are achieved using signal amplification by reversible exchange (SABRE) combined with the multiplet‐refocusing technique, SHARPER (Sensitive, Homogeneous, And Resolved PEaks in Real time).
Ana I. Silva Terra, Meghan E. Halse
wiley   +1 more source