ABSTRACT The ripening of climacteric fruits is characterised by a sharp increase in ethylene production, coinciding with the conversion of starch into soluble sugars. However, the regulatory interplay between ethylene and starch degradation in apple remains largely unclear. Here, we report a negative correlation between starch accumulation and ethylene
Fan Xiao +8 more
wiley +1 more source
Optimizing antifungal dosing for invasive <i>Cryptococcus</i> infections: minimum inhibitory concentration distributions and pharmacokinetic/pharmacodynamic insights from 2010-2023 Antimicrobial Testing Leadership and Surveillance data. [PDF]
Liu CY +6 more
europepmc +1 more source
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin +7 more
wiley +1 more source
Cyclic Amide-Linked Oxazolidinone Triazoles as Inhibitors of the T-Box Riboswitch. [PDF]
Parsons E +6 more
europepmc +1 more source
Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem +9 more
wiley +1 more source
Integrated In Silico and In Vitro Study of Copper Nanocatalyzed Carbonyl-Functionalized Triazoles-Inducing S Phase Cell Cycle Arrest and Apoptosis in MCF-7. [PDF]
Mondal J +10 more
europepmc +1 more source
Abstract CO2 solubility in deep eutectic solvent (DES) is a critical property to indicate the competence of using DESs for carbon capture. This work presents a systematic screening framework with computational and experimental procedures to identify the promising ammonium‐based DESs for CO2 absorption.
Hao Qin +3 more
wiley +1 more source
Novel 1<i>H</i>-1,2,3-Triazole Derivatives of Praziquantel with TRPM<sub>PZQ</sub> Modulatory Activity and Antiparasitic Effects on Larvae, Juvenile, and Adult Worms of <i>Schistosoma mansoni</i>. [PDF]
Junior FPS +14 more
europepmc +1 more source

