Expression of bovine cytosolic 5'-nucleotidase (cN-II) in yeast: nucleotide pools disturbance and its consequences on growth and homologous recombination. [PDF]
PLoS ONE, 2013 Cytosolic 5'-nucleotidase II is a widespread IMP hydrolyzing enzyme, essential for cell vitality, whose role in nucleotide metabolism and cell function is still to be exactly determined.
Simone Allegrini +6 more
doaj +2 more sources
Mediators of Inflammation, 2015 AMP dephosphorylation via ecto-5′-nucleotidase/CD73 is the rate limiting step to generate extracellular adenosine (ADO) from released adenine nucleotides. ADO, via A2A receptors (A2ARs), is a potent modulator of neuromuscular and immunological responses.
Laura Oliveira +7 more
doaj +2 more sources
Serum 5'-Nucleotidase as a Novel Predictor of Adverse Clinical Outcomes after Percutaneous Coronary Intervention in Patients with Coronary Artery Disease. [PDF]
Rev Cardiovasc MedBackground: The correlation between 5′-Nucleotidase (5′-NT) and the clinical outcomes in coronary artery disease (CAD) patients following percutaneous coronary intervention (PCI) is not clear. This study aims to clarify this relationship.
Aimaitijiang M +6 more
europepmc +2 more sources
Exacerbation of Allergic Airway Inflammation in Mice Lacking ECTO-5'-Nucleotidase (CD73). [PDF]
Front Pharmacol, 2020 The airways are a target tissue of type I allergies and atopy is the main etiological factor of bronchial asthma. A predisposition to allergy and individual response to allergens are dependent upon environmental and host factors.
Caiazzo E +10 more
europepmc +2 more sources
The elegant complexity of mammalian ecto-5'-nucleotidase (CD73). [PDF]
Trends Cell Biol, 2021 Purinergic signaling is a fundamental mechanism used by all cells to control their internal activities and interact with the environment. A key component of the purinergic system, the enzyme ecto-5'-nucleotidase (CD73) catalyzes the last step in the ...
Alcedo KP, Bowser JL, Snider NT.
europepmc +2 more sources
Autoimmunity in CD73/Ecto-5'-nucleotidase deficient mice induces renal injury. [PDF]
PLoS ONE, 2012 Extracellular adenosine formed by 5'-ectonucleotidase (CD73) is involved in tubulo-glomerular feedback in the kidney but is also known to be an important immune modulator.
Cornelia Blume +6 more
doaj +2 more sources
About Pyrimidine 5’-Nucleotidase Deficiency
Turkish Journal of Hematology, 2013 Şinasi Özsoylu
openaire +4 more sources
Clinical utility of anti-cytosolic 5'-nucleotidase 1A antibody in idiopathic inflammatory myopathies. [PDF]
Ann Clin Transl Neurol, 2021 To define the clinicopathologic features and diagnostic utility associated with anti‐cytosolic 5′‐nucleotidase 1A (NT5C1A) antibody seropositivity in idiopathic inflammatory myopathies (IIMs).
Ikenaga C +13 more
europepmc +2 more sources
Ectonucleoside triphosphate diphosphohydrolases and ecto-5'-nucleotidase in purinergic signaling: how the field developed and where we are now. [PDF]
Purinergic Signal, 2021 Geoffrey Burnstock will be remembered as the scientist who set up an entirely new field of intercellular communication, signaling via nucleotides. The signaling cascades involved in purinergic signaling include intracellular storage of nucleotides ...
Zimmermann H.
europepmc +2 more sources