Efficacy and Tolerability of 6-Month Treatment with Tamsulosin Plus the Hexanic Extract of Serenoa repens versus Tamsulosin Plus 5-Alpha-Reductase Inhibitors for Moderate-to-Severe LUTS-BPH Patients: Results of a Paired Matched Clinical Study. [PDF]
J Clin Med, 2022 Alcaraz A +18 more
europepmc +1 more source
A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)
Developmental Dynamics, EarlyView.Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble +2 more
wiley +1 more source
European Journal of Inorganic Chemistry, EarlyView.Rollover cyclometalation is a distinctive variant of classical cyclometalation where a chelated heterocyclic ligand undergoes internal rotation, releasing one donor atom from coordination and subsequently activating a remote C─H bond with high regioselectivity.
Antonio Zucca, Maria I. Pilo
wiley +1 more source
Change in hair growth-related gene expression profile in human isolated hair follicles induced by 5-alpha reductase inhibitors - dutasteride and finasteride - in the presence of testosterone. [PDF]
Singapore Med J, 2022 Hatanaka T +5 more
europepmc +1 more source
Design and synthesis of non-steroidal inhibitors of 5[alpha]-reductase
Androgen-dependent prostate cancer (PC) and benign prostate hyperplasia (BPH) can be treated either by surgical resection or through the use of drugs that produce androgen deprivation.
Denison, Sophie
core
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
The impact of 5-alpha reductase inhibitors on multiparametric MRI diagnostic performance and prostate-specific antigen density triage: A systematic review. [PDF]
BJUI CompassHarrison G +4 more
europepmc +1 more source
Flavour and Fragrance Journal, EarlyView.This review bridges ancestral indigenous knowledge with modern pharmacology, summarizing the phytochemistry and antimicrobial properties of essential oils from seven native American species. It highlights their significant activity against bacterial, fungal and parasitic pathogens, emphasizing their potential as sustainable therapeutic and agricultural
Arley Rey Páez +2 more
wiley +1 more source
Food Biomacromolecules, EarlyView.Non‐animal extracellular vesicles as bioactive‐compound carriers: compositional characteristics, engineering strategies, and biofunctions. Abstract Animal‐derived extracellular vesicles (EVs) were widely used for bioactive compound delivery but constrained by complex origins, potential immunogenicity, and pathogen contamination.
Jiahao Yu +6 more
wiley +1 more source