Results 71 to 80 of about 46,559 (243)

PSA Dynamics in Patients with BPH and Patients Treated with 5.Alpha Reductase Inhibitors

open access: yes, 2014
Serum PSA gives information about the future increase of prostate volume, deterioration of symptoms and patient`s anxiety, sexual dysfunction, deterioration of urinary flow and risk of urinary retention and prostate surgery. Higher PSA strongly indicates
Petkova, Lidiya; Medical university of Varna   +3 more
core   +1 more source

NQO2 is a reactive oxygen species generating off-target for acetaminophen [PDF]

open access: yes, 2014
The analgesic and antipyretic compound acetaminophen (paracetamol) is one of the most used drugs worldwide. Acetaminophen overdose is also the most common cause for acute liver toxicity.
Teemu P. Miettinen   +3 more
core   +1 more source

New Potent 5α- Reductase and Aromatase Inhibitors Derived from 1,2,3-Triazole Derivative

open access: yes, 2020
This work describes the utility of pyrazole-4-carbaldehyde 1 as starting material for the synthesis of a novel potent series of 5α-reductase and aromatase inhibitors derived from 1,2,3-triazole derivative.
Shweekar I. A. El-Naem   +4 more
core   +1 more source

Synergistic Advanced Oxidation and Physicochemical Treatment Strategies for Antibiotic Removal and Resistance Mitigation in Water

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The presence of antibiotics in water not only causes environmental pollution but also increases the growth of antibiotic‐resistant bacterial genes, which pose serious threats to human beings and other water residents. Large numbers of people are reportedly affected by the resistant bacterial genes, as many broad‐spectrum antibiotics are not ...
Amir Zada, Shohreh Azizi
wiley   +1 more source

Longitudinal Modulation of the Gut Microbiome and Growth Performance by Phytochemicals as Antibiotic Alternatives in Swine Production

open access: yesAnimal Research and One Health, EarlyView.
We conducted a longitudinal trial across nursery, growing, and finishing phases, showing that phytochemical supplementation as a potential antibiotic alternative reduced potential pathogens and promoted beneficial Lactobacillus amylovorus in the nursery phase, and enriched amino acid and carbohydrate metabolism pathways (prediction) during finishing ...
Ziyu Liu   +11 more
wiley   +1 more source

Differential expression of 5-alpha reductase isozymes in the prostate and its clinical implications

open access: yes, 2014
The development of human benign or malignant prostatic diseases is closely associated with androgens, primarily testosterone (T) and dihydrotestosterone (DHT). T is converted to DHT by 5-alpha reductase (5-AR) isozymes.
Nian-Zeng Xing   +4 more
core   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

open access: yesAnimal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang   +6 more
wiley   +1 more source

Prediction of adverse effects in patients with benign prostatic hyperplasia treated with 5 alpha reductase inhibitors [PDF]

open access: yes, 2019
Five alfa reductase inhibitors (5ARI) are widely used for treatment of benign prostatic hyperplasia (BPH) as they have a positive impact on the reduction of prostate volume and PSA levels, but also lead to adverse effects: erectile dysfunction, depressed
Sofronievska, Maja, Jovevska, Svetlana
core  

Comprehensive Characterization of Acer truncatum Leaf Extract: Identification of Systemic Metabolites and Effects on Performance, Antioxidant Status, and Intestinal Microbiota in Laying Hens

open access: yesAnimal Research and One Health, EarlyView.
Dietary A. truncatum leaf extract is absorbed and improves laying performance in aged hens by enhancing systemic antioxidant capacity and modulating the gut microbiota. ABSTRACT The demand for natural feed additives is considerably increasing in the antibiotic‐free feed era.
Kailong Qin   +6 more
wiley   +1 more source

Design and Synthesis of 1,2,4-Oxadiazole Derivatives as Non-Steroidal 5 Alpha-Reductase Inhibitors

open access: yes, 2009
The purpose of this study was to synthesize compounds in which the 1,2,4- oxadiazole moiety replaced the amide bond of ONO3805 and to evaluate its 5 alpha-reductase inhibitory activity as a potential benign prostatic hyperplasia therapeutic target.
CHERN, JI-WANG, 陳基旺
core  

Home - About - Disclaimer - Privacy