Results 71 to 80 of about 12,954,964 (236)

Host‐Specific Interactions Between Staphylococcus aureus and Pseudomonas aeruginosa Impair Epithelial Repair in Chronic Rhinosinusitis

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is frequently associated with polymicrobial biofilms involving Staphylococcus aureus and Pseudomonas aeruginosa. Interactions between these organisms are thought to influence disease severity, but the epithelial effects of exoproteins derived from patient‐matched cocultures remain poorly defined ...
Xiaohan Sun   +6 more
wiley   +1 more source

Baseline characteristics of the study base for 5 alpha reductase inhibitors (5-ARI) exposed with known start date and selected non-exposed men.

open access: yes, 2015
SD, Standard deviation. ANGII, Angiotensin II Inhibitors. CCI, Charlson weighted comorbidity index. TURP, Transurethral resection of prostateBaseline characteristics of the study base for 5 alpha reductase inhibitors (5-ARI) exposed with known start date
David Robinson (73947)   +3 more
core   +1 more source

Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome

open access: yesAnnals of Neurology, EarlyView.
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca   +24 more
wiley   +1 more source

Reduced Prostate Cancer Risk in Patients with Androgenetic Alopecia Using 5-Alpha Reductase Inhibitors: A TriNetX Real-World Cohort Study

open access: yes
Supplementary materials for the manuscript titled "Reduced Prostate Cancer Risk in Patients with Androgenetic Alopecia Using 5-Alpha Reductase Inhibitors: A TriNetX Real-World Cohort Study"
Chen, Yu-Jen
core   +1 more source

Novel Lead Generation through Hypothetical Pharmacophore Three-Dimensional Database Searching:  Discovery of Isoflavonoids as Nonsteroidal Inhibitors of Rat 5α-Reductase

open access: yes, 2016
A hypothetical pharmacophore of 5α-reductase inhibitors was generated and served as a template in virtual screening. When the pharmacophore was used, eight isoflavone derivatives were characterized as novel potential nonsteroidal inhibitors of rat 5α ...
Chih-Shiang Chang (2361178)   +5 more
core   +1 more source

Mycothiol disulfide reductase as a drug target [PDF]

open access: yes, 2010
Includes abstract. Includes bibliographical references (leaves 154-171)
Mavumengwana, Vuyo Bhongolethu
core   +1 more source

Alpha Kappa Alpha EAF Awards luncheon program, July 15, 2014

open access: yes, 2014
This program for the Educational Advancement Foundation (EAF) Awards luncheon given by the Alpha Kappa Alpha sorority notes the sequence of events, leaders of the EAF, and sponsors for the gathering.Archival master image scanned in reflective mode as 48 ...
Alpha Kappa Alpha
core   +1 more source

Discovery of an Antiviral Electron Transfer Process to Create Catalytically Self‐Sufficient Viral Restriction Factors

open access: yesAngewandte Chemie International Edition, EarlyView.
CYB5R3 is identified as a putative electron‐transfer partner of viperin (RSAD2), explaining why ER localisation is required for antiviral activity. Its utilisation enabled the engineering of immune‐silent, catalytically self‐sufficient antiviral restriction factor enzymes (iCAREs) that produce an antiviral nucleoside triphosphate analogue (ANTA ...
Mengdi Wu   +16 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Human steroid 5-alpha reductase, isoform S5A1_HUMAN.

open access: yes, 2013
Enzyme human steroid 5-alpha reductase, isoform S5A1_HUMAN (SRD5A1 gene) in the Main cluster. The number after HUMAN indicates the length of the protein.
Annamaria Vernone (399045)   +2 more
core   +1 more source

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