Results 71 to 80 of about 79,532,914 (276)

Inhibition of 5 alpha-reductase in the rat prostate by Cimicifuga racemosa

open access: yes, 2006
Objectives: Prostate cancers and many thereof derived cell lines, as the LNCaP cells, grow androgen-dependent. In vivo testosterone is locally converted by 5 alpha-reductase to 5 alpha-dihydrotestosterone (5 alpha-DHT) which is the major androgenic ...
Wuttke, Wolfgang   +3 more
core   +1 more source

Combination therapy with dutasteride and tamsulosin for the treatment of symptomatic enlarged prostate

open access: yesClinical Interventions in Aging, 2009
J Miller, TH TarterSouthern Illinois University School of Medicine, Department of Surgery, Springfield, IL, USAAbstract: Benign prostatic hyperplasia (BPH) is a frequent cause of lower urinary symptoms, with a prevalence of 50% by the sixth decade of ...
J Miller, TH Tarter
doaj  

The CXCL5/CXCR2 Axis Attenuates Ferroptosis in Intrahepatic Cholangiocarcinoma Through the Positive Feedback Loop Between PTGS2 Transcriptional Activation and Neutrophil Recruitment

open access: yesAdvanced Science, EarlyView.
The CXCL5/CXCR2 axis directly inhibits ferroptosis in ICC cells by activating the NF‐κB/PTGS2 pathway. Meanwhile, the CXCL5/CXCR2 axis recruits N2 TANs, and the activated PTGS2 promotes the secretion of TNF‐α from the recruited N2 TANs via the CCL2/CCL7/CCR2 pathway, thereby activating the NF‐κB/PTGS2 axis and forming a positive feedback loop, which ...
Chanqi Ye   +17 more
wiley   +1 more source

5 alpha-Reductase inhibitor is less effective in men with small prostate volume and low serum prostatic specific antigen level

open access: yes, 2017
Background/Purpose: Large total prostate volumes (TPVs) or high serum prostate-specific antigen (PSA) levels indicate high-risk clinical progression of benign prostatic hyperplasia.
Lin, Victor C.;Liao, Chun-Hou;Wang, Chung-Cheng;Kuo, Hann-Chorng
core   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

open access: yesAdvanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan   +5 more
wiley   +1 more source

Reduced Prostate Cancer Risk in Patients with Androgenetic Alopecia Using 5-Alpha Reductase Inhibitors: A TriNetX Real-World Cohort Study

open access: yes
Supplementary materials for the manuscript titled "Reduced Prostate Cancer Risk in Patients with Androgenetic Alopecia Using 5-Alpha Reductase Inhibitors: A TriNetX Real-World Cohort Study"
Chen, Yu-Jen
core   +1 more source

PSA Dynamics in Patients with BPH and Patients Treated with 5.Alpha Reductase Inhibitors [PDF]

open access: yes, 2014
Serum PSA gives information about the future increase of prostate volume, deterioration of symptoms and patient`s anxiety, sexual dysfunction, deterioration of urinary flow and risk of urinary retention and prostate surgery. Higher PSA strongly indicates
Petkova, Lidiya; Medical university of Varna   +3 more
core   +1 more source

Herbivory‐Induced Stomatal Opening Triggers the Dispersal of an Invasive Insect Herbivore

open access: yesAdvanced Science, EarlyView.
The invasive leafminer Phthorimaea absoluta uniquely manipulates plant defenses by inducing stomatal opening in tomato. This response, mediated by the stomatal regulator IQM1, enhances the release of the repellent volatile benzaldehyde. This volatile triggers the dispersal of adult moths, facilitates colonization of new hosts, and leads to rapid ...
Limin Chen   +10 more
wiley   +1 more source

[Impact of preoperative therapy with 5-α-reductase inhibitors in the treatment of benign prostatic hyperplasia]

open access: yes, 2012
Benign prostatic hyperplasia is considered a progressive disease intimately linked with aging. The long-term use of combination therapy with a 5-alpha-reductase inhibitor, together with an alpha blocker in men with moderate-severe symptoms, reduces the ...
De Stefano G.   +6 more
core   +1 more source

5-alpha reductase inhibitors, benign prostatic hyperplasia, and risk of male breast cancer [PDF]

open access: yes, 2015
5-alpha reductase inhibitors (5-ARI) have been suggested to increase the risk of male breast cancer. The aim of this study was to study the risk of breast cancer in men on 5-ARI, in men with benign prostatic hyperplasia (BPH) not on 5-ARI, and in men ...
Lars Holmberg   +11 more
core   +1 more source

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