Influence of Light Exposure on the Kinetics of Protoporphyrin IX Formation in Normal Skin of Hairless Mice After Application of 5-Aminolevulinic Acid Methyl Ester [PDF]
Journal of Investigative Dermatology, 2005 The rates of protoporphyrin IX (PpIX) photodegradation and reappearance after light exposure at 420 and 632 nm were measured in mouse skin at different times after 1 h topical application of 5-aminolevulinic acid methyl ester (ALA-Me). After ALA-Me application (1 h) and removal, the fluorescence of PpIX increased for about 1 h, and then reached a ...
Moan, Johan +3 more
openaire +2 more sources
Photodynamic therapy in the treatment of onychomycosis – a review
Przegląd Dermatologiczny, 2017 Toenail onychomycosis is a common infection, affecting up to 14% of the population. Moreover, poor penetration of topical drugs into the nail bed leads to frequent recurrences of the disease. The cure rate of toenail onychomycosis is estimated at 63–76%.
Katarzyna Kalinowska +1 more
doaj +1 more source
Modulation of 5-Aminolevulinic acid mediated photodynamic therapy induced cell death in a human lung adenocarcinoma cell line [PDF]
, 2016 Photodynamic therapy (PDT) is a cancer treatment involving the administration of a photosensitising drug which selectively accumulates in tumor tissue, followed by irradiation with appropriate wavelength light.
Battle, A. +3 more
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Menthol and Its Derivatives: Exploring the Medical Application Potential. [PDF]
Eng Life SciABSTRACT Menthol, a natural organic compound and the primary component of mint, exhibits diverse biological activities, including analgesic, anti‐inflammatory, antibacterial, neuroprotective, and anticancer effects. The chemical modification of menthol, through processes such as esterification and amination, further enhances these activities, expanding
Zhang J, Hu Y, Wang Z.
europepmc +2 more sources
Enhancing protoporphyrin IX-induced photodynamic therapy with a topical iron chelating agent in a normal skin model [PDF]
, 2016 PublishedArticle© Under License of Creative Commons Attribution 3.0 LicenseProtoporphyrin IX (PpIX)-induced photodynamic therapy (PDT) is being utilised within dermatological practice as a topical method of localised ablation of non-melanoma skin cancer ...
Bown, SG, Curnow, Alison, MacRobert, AJ
core +1 more source
Overview on topical 5-ALA photodynamic therapy use for non melanoma skin cancers [PDF]
, 2014 Ultraviolet radiation (UV) contributes to a variety of skin diseases including inflammation, degenerative aging, and cancer. Historically, humans have been exposed to UV radiation mainly through occupational exposure; recreational UV exposure, however ...
Bianchini, Daniela +7 more
core +3 more sources
The effects of protoporphyrin IX-induced photodynamic therapy with and without iron chelation on human squamous carcinoma cells cultured under normoxic, hypoxic and hyperoxic conditions. [PDF]
, 2016 BACKGROUND: Photodynamic therapy requires the combined interaction of a photosensitiser, light and oxygen to ablate target tissue. In this study we examined the effect of iron chelation and oxygen environment manipulation on the accumulation of the ...
Allen, James +2 more
core +1 more source
Enhancement of methyl-aminolevulinate photodynamic therapy by iron chelation with CP94: an in vitro investigation and clinical dose-escalating safety study for the treatment of nodular basal cell carcinoma. [PDF]
, 2016 Clinical TrialAuthor version of article. The final publication is available at Springer via: http://dx.doi.org/10.1007/s00432-008-0358-6PURPOSE: Methyl-aminolevulinate (MAL) photodynamic therapy (PDT) is a cancer therapy that combines the selective ...
Campbell, Sandra M. +2 more
core +1 more source
Photodynamic therapy of Bowen’s disease
Biomedical PhotonicsBowen’s disease is a form of non-invasive (in situ) squamous cell skin cancer localized in the non-genital area. Russian and European clinical guidelines include photodynamic therapy (PDT) in the standard of care for patients with Bowen’s disease. In the
E. V. Filonenko, V. I. Ivanova-Radkevich
doaj +1 more source
The relationship between protoporphyrin IX photobleaching during real-time dermatological methyl-aminolevulinate photodynamic therapy (MAL-PDT) and subsequent clinical outcome. [PDF]
, 2016 Journal Article"This is the peer reviewed version of the following article: Lasers in Surgery and Medicine 42:613–619 (2010), which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1002/lsm.20943/pdf. This article may be used for
Campbell, Sandra M. +2 more
core +1 more source