Homology modeling of human γ-butyric acid transporters and the binding of pro-drugs 5-aminolevulinic acid and methyl aminolevulinic acid used in photodynamic therapy. [PDF]
PLoS ONE, 2013 Photodynamic therapy (PDT) is a safe and effective method currently used in the treatment of skin cancer. In ALA-based PDT, 5-aminolevulinic acid (ALA), or ALA esters, are used as pro-drugs to induce the formation of the potent photosensitizer ...
Yan Baglo +3 more
doaj +1 more source
Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy [PDF]
, 1999 Purpose: We determined whether neoplastic disease, which was missed under white light can be found during transurethral resection of bladder cancer by 5-aminolevulinic acid-induced porphyrin fluorescence.
Kriegmair, Martin +13 more
core +1 more source
Kinetics of 5-aminolevulinic acid-induced fluorescence in organ cultures of bronchial epithelium and tumor [PDF]
, 2002 Background: 5-Aminolevulinic acid (5-ALA)-induced protoporphyrin IX (PPIX) fluorescence improves the differentiation of tumor and normal tissue in the bladder, skin and brain. Objective: The kinetics of 5-ALA-induced protoporphyrin IX (PPIX) fluorescence
Bergner, Albrecht +8 more
core +1 more source
Photodynamic therapy of prostate cancer by means of 5-aminolevulinic acid-induced protoporphyrin IX - In vivo experiments on the dunning rat tumor model [PDF]
, 2004 Objective: In order to expand the use of photodynamic therapy (PDT) in the treatment of prostate carcinoma (PCA), the aim of this study was to evaluate PDT by means of 5-aminolevulinic acid (5-ALA)-induced protoporphyrin IX ( PPIX) in an in vivo tumor ...
Schneede, Peter +12 more
core +1 more source
Biophysical aspects of photodynamic therapy [PDF]
, 2012 Photodynamic therapy (PDT) is a multimodality cancer treatment available for the palliation or eradication of systemic and cutaneous malignancies. In this thesis, the application of PDT is for the treatment of non-melanoma skin cancer (NMSC).
Valentine, Ronan
core +2 more sources
Photodynamic therapy in the treatment of onychomycosis – a review
Przegląd Dermatologiczny, 2017 Toenail onychomycosis is a common infection, affecting up to 14% of the population. Moreover, poor penetration of topical drugs into the nail bed leads to frequent recurrences of the disease. The cure rate of toenail onychomycosis is estimated at 63–76%.
Katarzyna Kalinowska +1 more
doaj +1 more source
Crystal structure of the N-benzyloxycarbonyl-Alanyl-Phenylalanyl-methyl ester: the importance of the H-bonding pattern [PDF]
, 2011 Large crystals of the methyl ester of the N-a-benzyloxycarbonyl protected Ala-Phe dipeptide (Z-AF-OMe) were obtained after the very slow evaporation of a solution of the corresponding carboxylic acid (Z-AF-OH) in methanol containing an excess of HCl. The
Bolte, Michael +9 more
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Allylic oxidation of ent-Kaurenic acid, ent-Kaurenic acid Methyl Ester and ent-Kaurenol. [PDF]
, 2015 The allylic oxidation of ent-kaurenic acid, ent-kaurenic acid methyl ester, and ent-kaurenol with SeO2/H2O2 is presented. The reaction was run in dioxan solution at room temperature stirring for 4 hours.
Bahsas B., Alí H. +2 more
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Experimental Study on the Production of Karanja Oil Methyl Ester and Its Effect on Diesel Engine [PDF]
, 2012 Fast depletion of fossil fuel resources forces the extensive research on the alternative fuels. Vegetable oils edible or non edible can be a better substitute for the petroleum diesel.
N , Shrivastava, +2 more
core +2 more sources
5-Aminolevulinic acid synthase: mechanism, mutations and medicine
, 2003 5-Aminolevulinic acid synthase (ALAS), the first enzyme of the heme biosynthesis pathway, catalyses the pyridoxal 5'-phosphate-dependent condensation between glycine and succinyl-CoA to yield 5-aminolevulinic acid (5-amino-4-oxopentanoate).
Bottomley, S.S. +11 more
core +1 more source