Enhancement of methyl-aminolevulinate photodynamic therapy by iron chelation with CP94: an in vitro investigation and clinical dose-escalating safety study for the treatment of nodular basal cell carcinoma. [PDF]
Clinical TrialAuthor version of article. The final publication is available at Springer via: http://dx.doi.org/10.1007/s00432-008-0358-6PURPOSE: Methyl-aminolevulinate (MAL) photodynamic therapy (PDT) is a cancer therapy that combines the selective ...
Campbell, Sandra M. +2 more
core +1 more source
P450BM3-Catalyzed Oxidations Employing Dual Functional Small Molecules [PDF]
A set of dual functional small molecules (DFSMs) containing different amino acids has been synthesized and employed together with three different variants of the cytochrome P450 monooxygenase P450BM3 from Bacillus megaterium in H2O2-dependent oxidation
Girhard, Marco +5 more
core +1 more source
Photodynamic therapy of cutaneous squamous cell carcinoma
Photodynamic therapy has traditionally been used and approved in many countries for the treatment of intraepithelial forms of cutaneous squamous cell carcinoma and precancer – actinic keratosis and Bowen’s disease.
E. V. Filonenko, V. I. Ivanova-Radkevich
doaj +1 more source
Long-term Outcome of Low-concentration Hexyl-5-aminolaevulinate Daylight Photodynamic Therapy for Treatment of Actinic Keratoses [PDF]
Peer ...
Gronroos, Mari +4 more
core +1 more source
Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio +4 more
wiley +1 more source
Breast cancer as photodynamic therapy target: Enhanced therapeutic efficiency by overview of tumor complexity [PDF]
Photodynamic therapy is a minimally invasive and clinically approved procedure for eliminating selected malignant cells with specific light activation of a photosensitizer agent.
Lamberti, María Julia +2 more
core +1 more source
Polysaccharides play a pivotal role in the development of safe and healthy foods. They ameliorate fatigue, preserve the microflora of the gastrointestinal tract, and provide health for the gut in living organisms. These biopolymers are applied for the fabrication of breakthrough drug delivery systems and potential platforms in regenerative medicine ...
M V N L Chaitanya +14 more
wiley +1 more source
Modelling topical photodynamic therapy treatment including the continuous production of Protoporphyrin IX [PDF]
C L Campbell acknowledges financial support from an UK EPSRC PhD studentship (EP/K503162/1) and the Alfred Stewart Trust.Most existing theoretical models of photodynamic therapy (PDT) assume a uniform initial distribution of the photosensitive molecule ...
C L Campbell +10 more
core +2 more sources
Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi +4 more
wiley +1 more source
The Adverse Effects of Topical Photodynamic Therapy:a consensus review and approach to management [PDF]
Background: Topical photodynamic therapy (PDT) is widely used to treat superficial nonmelanoma skin cancer and dysplasia, and is generally well tolerated.
Babilas P +17 more
core +2 more sources

