Results 11 to 20 of about 344,744 (207)

Therapy of Inflammatory Bowel Disease using 5-Aminosalicylic Acid, 4-Aminosalicylic Acid and Olsalazine Retention Enemas: Review of Clinical Trials

Canadian Journal of Gastroenterology, 1989
The knowledge that 5-aminosalicylic acid (5-ASA) is the active compound of sulphasalazine and that it acts topically has stimulated the use of 5-ASA containing enemas and ocher similar compounds such as olsalazine and 4-aminosalicylic acid (4-ASA). 5-ASA
M. Campieri, P. Gionchetti, A. Belluzzi, C. Brignola, P. Iannone, M. Miglioli, L. Barbara   +6 more
doaj   +2 more sources

Synthesis, characterization and radical scavenging activity of aromatic amine conjugates of 5-aminosalicylic acid

Bulletin of the Chemical Society of Ethiopia, 2014
5-Aminosalicylic acid is an anti-inflammatory drug used in the treatment of inflammatory bowel diseases including ulcerative colitis and Crohn’s disease.
K. Harveer, , S. Jasmeen
doaj   +3 more sources

Renal Effects of Long-Term Treatment with 5-Aminosalicylic Acid [PDF]

Canadian Journal of Gastroenterology, 2009
BACKGROUND: A number of case reports link the use of 5-aminosalicylic acid (5-ASA) to interstitial nephritis in patients with inflammatory bowel disease (IBD).
Harshna Patel, Aiala Barr, Khursheed N Jeejeebhoy   +2 more
doaj   +2 more sources

Application of 5-Aminosalicylic Acid Preparations in the Treatment of Inflammatory Bowel Diseases

Gastroenterologìa, 2016
The article is devoted to the comparative characterization of different derivatives of 5-aminosalicylic acid. Researches of the past decades have changed the presentation of the potential use of aminosalicylates in the therapy of various inflammatory ...
Yu.M. Stepanov, M.V. Stoykevich, O.V. Sorochan   +2 more
doaj   +2 more sources

Sonoelectrochemically enhanced determination of 5-aminosalicylic acid

Talanta, 2001
The electrochemical detection of the anti-inflammatory drug 5-aminosalicylic acid (5-ASA) has been evaluated through the application of linear sweep, square wave and sonolinear sweep voltammetry. The introduction of ultrasound is shown to significantly enhance the oxidation signal intensity thereby enabling the detection of low concentrations with the ...
Beckett, E, Lawrence, N, Evans, R, Davis, J, Compton, R   +4 more
openaire   +4 more sources

Synthesis and evaluation of mutual azo prodrug of 5-aminosalicylic acid linked to 2-phenylbenzoxazole-2-yl-5-acetic acid in ulcerative colitis

Drug Design, Development and Therapy, 2013
Jamal A Jilani,1 Maha Shomaf,2 Karem H Alzoubi3 1Department of Medicinal Chemistry and Pharmacognosy, Jordan University of Science and Technology, Irbid, Jordan; 2Department of Pathology, Jordan University, Amman, Jordan; 3Department of Clinical Pharmacy,
Jilani JA, Shomaf M, Alzoubi KH
doaj   +1 more source

Lupus-Like Syndrome Caused by 5-Aminosalicylic Acid in Patients with Inflammatory Bowel Disease

Canadian Journal of Gastroenterology, 1999
BACKGROUND: Although 5-aminosalicylic acid (5-ASA) preparations used to treat inflammatory bowel disease are reported to have fewer side effects than sulphasalazine, increased clinical use of these compounds has resulted in increased reports of ...
Andrew W Kirkpatrick, Arthur A Bookman, Flavio Habal   +2 more
doaj   +2 more sources

Synthesis and Antibacterial Evaluation of 5-Aminosalicylic Acid Derivatives

Applied Sciences
The anti-inflammatory scaffold 5-aminosalicylic acid, which is widely used in therapeutic applications, was chosen for the synthesis of N-[3-(hydrazinecarbonyl)-4-hydroxyphenyl]acetamide (1) to enhance its antibacterial properties.
Kazimieras Anusevičius, Jūratė Šiugždaitė, Birutė Sapijanskaitė-Banevič, Valentas Špiliauskas, Birutė Grybaitė, Livija Tubytė, Vytautas Mickevičius   +6 more
doaj   +2 more sources

Concomitant 5-Aminosalicylic Acid Does Not Affect the Efficacy of Janus Kinase Inhibitors in Ulcerative Colitis. [PDF]

Clin Pharmacol Ther
We evaluated whether concomitant 5‐aminosalicylic acid (5‐ASA) influences clinical remission in patients with ulcerative colitis (UC) receiving Janus kinase inhibitors (JAKi). In this retrospective, multicenter cohort study, UC patients receiving tofacitinib (n = 181), upadacitinib (n = 313), or filgotinib (n = 139) were included.
Tursi A, Pasta A, Elisei W, Barberio B, Mocci G, Maconi G, Gravina AG, Pellegrino R, Bodini G, Savarino EV, Papa A, Italian Network for Inflammatory Bowel Diseases (IN‐IBD).   +11 more
europepmc   +2 more sources

4‑Aminosalicylic Acid Adducts

, 2016
4-Aminosalicylic acid (p-aminosalicylic acid, PAS), an antituberculosis drug, is a model active pharmaceutical ingredient to study salt and cocrystal formation in a multiple hydrogen-bonding functionality molecule with carboxylic acid, amine, and phenol ...
Geetha Bolla (1744141), Kanishka Sikligar (1974430), Ashwini Nangia (1400761), Suryanarayan Cherukuvada (1576204)   +3 more
core   +7 more sources