Results 31 to 40 of about 344,744 (207)

Effect of acid-reducing agents on clinical relapse in ulcerative colitis with pH-dependent-released 5-aminosalicylic acid: a multicenter retrospective study in Japan [PDF]

Intestinal Research, 2021
Background/Aims 5-Aminosalicylic acid (5-ASA) is a basic drug for inducing and maintaining remission for ulcerative colitis. One of its formulations has a coating with a pH-dependent degradation that ensures the release 5-ASA at the terminal ileum.
Yosuke Shimodaira, Kengo Onochi, Kenta Watanabe, So Takahashi, Sho Fukuda, Noboru Watanabe, Shigeto Koizumi, Tamotsu Matsuhashi, Katsunori Iijima   +8 more
doaj   +1 more source

5-Aminosalicylic acid aggravates colitis mimicking exacerbation of ulcerative colitis [PDF]

Intestinal Research, 2018
Ulcerative colitis (UC) is one of the major clinical phenotypes of inflammatory bowel diseases. Although 5-aminosalicylic acid (5-ASA) is widely used for UC and its efficacy and safety have been demonstrated, a few patients paradoxically develop a severe
Jun Miyoshi, Katsuyoshi Matsuoka, Atsushi Yoshida, Makoto Naganuma, Tadakazu Hisamatsu, Tomoharu Yajima, Nagamu Inoue, Susumu Okamoto, Yasushi Iwao, Haruhiko Ogata, Fumiaki Ueno, Toshifumi Hibi, Takanori Kanai   +12 more
doaj   +1 more source

Prospects of MMX Mesalazine in Routine Outpatient Treatment of Ulcerative Colitis

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2022
Aim. A general review of treatment approaches to ulcerative colitis (UC) and the importance of oral 5-aminosalicylic acid (5-ASA) for its routine outpatient management.Key points.
Yu. P. Uspenskiy, S. V. Ivanov, Yu. A. Fominykh   +2 more
doaj   +1 more source

Pancreatitis: common but forgotten causes

Медицинский вестник Юга России, 2021
Objective: to study the causes of pancreatitis. Materials and methods: a clinical case of acute pancreatitis during the treatment of ulcerative colitis with 5-aminosalicylic acid-containing drugs.
E. R. Donсova, O. V. Remizov, N. V. Novoselya   +2 more
doaj   +1 more source

Controlled Release of 5-Aminosalicylic Acid (5-ASA) from New Biodegradable Polyurethanes

Molecules, 2010
Segmented polyurethanes containing azo aromatic groups in the main chain were synthesized by reaction of 3,3'-azobis(6-hydroxybenzoic acid) (ABHB), 5-[4-(hydroxyphenyl)azo] salicylic acid (HPAS), and 5-[1-hydroxynaphthyl)azo] salicylic acid (HNAS) with ...
El-Refaie Kenawy, Salem S. Al-Deyab, Mohamed H. El-Newehy   +2 more
doaj   +1 more source

Oxidation of Mesalamine under Phenoloxidase- or Peroxidase-like Enzyme Catalysis

Molecules, 2023
Mesalamine, also called 5-ASA (5-aminosalicylic acid), is a largely used anti-inflammatory agent and is a main choice to treat Ulcerative Colitis. This report is aimed to investigate enzymatic processes involved in the oxidation of mesalamine to better ...
Rimaz El Zein, Pompilia Ispas-Szabo, Maziar Jafari, Mohamed Siaj, Mircea Alexandru Mateescu   +4 more
doaj   +1 more source

Nephrotoxic Lesions from 5-Aminosalicylic Acid [PDF]

BMJ, 1972
5-Aminosalicylic acid given to rats as a single intravenous injection led to necrosis of the proximal convoluted tubules and of the renal papilla. These two lesions developed at the same time and the cortical lesions did not appear to be a consequence of the renal papillary necrosis.
I C, Calder, C C, Funder, C R, Green, K N, Ham, J D, Tange   +4 more
openaire   +2 more sources

Use of new, once-daily 5-aminosalicylic acid preparations in the treatment of ulcerative colitis. Is there anything new under the sun?

, 2009
5-aminosalicylate (5-ASA) agents remain the mainstay treatment in ulcerative colitis (UC). A number of oral 5-ASA agents are commercially available, including azobond pro-drugs, as well as delayed- and controlled-release forms of mesalazine.
Lakatos, Péter László
core   +1 more source

Preparation and in-vitro characterization of 5-aminosalicylic acid loaded hydrogels for colon specific delivery

Journal of Materials Research and Technology, 2022
The aim of the current investigation was to prepare and characterize the novel pH-sensitive hydrogels of pluronic F127 and sodium polystyrene sulfonate for the controlled delivery of 5-aminosalicylic acid to colon.
Muhammad Suhail, Ming-Chia Hung, I-Hui Chiu, Quoc Lam Vu, Pao-Chu Wu   +4 more
doaj   +1 more source

A novel dual-prodrug carried by cyclodextrin inclusion complex for the targeting treatment of colon cancer

Journal of Nanobiotechnology, 2021
Background There is an obvious correlation between ulcerative colitis and colorectal cancer, and the risk of colorectal cancer in patients with ulcerative colitis is increasing. Therefore, the combination therapy of anti-inflammatory and anti-tumor drugs
Lin Chen, Yan Lin, Zijun Zhang, Ruisheng Yang, Xiaosheng Bai, Zhongbing Liu, Zhongling Luo, Meiling Zhou, Zhirong Zhong   +8 more
doaj   +1 more source