Mesalazine induced focal segmental glomerulosclerosis in a patient with ulcerative colitis
Focal segmental glomerulosclerosis (FSGS) and other glomerulonephritis due to the use of 5-aminosalicylic acid derivatives have been reported in the literature. A 38-year-old male who had been using mesalazine for four years because of ulcerative colitis
Fatih Yilmaz +3 more
doaj +1 more source
The culprit of mesalamine intolerance: case series and literature review
Background Mesalamine is a first-line drug in the treatment of inflammatory bowel diseases, while its intolerance occasionally occurs in clinical practice.
Cheng Xie +5 more
doaj +1 more source
Budesonide Foam Has a Favorable Safety Profile for Inducing Remission in Mild-to-Moderate Ulcerative Proctitis or Proctosigmoiditis. [PDF]
BackgroundBudesonide foam, a rectally administered, second-generation corticosteroid with extensive hepatic first-pass metabolism, is efficacious for the treatment of mild-to-moderate ulcerative proctitis and ulcerative proctosigmoiditis.AimThe aim of ...
Barrett, Andrew C +10 more
core +3 more sources
To compare the effects of aminosalicylic acid, glucocorticoids and immunosuppressants on the expression levels of multidrug resistance genes in patients with ulcerative colitis (UC), with the aim of providing a theoretical and therapeutic basis for the ...
Yan Chen +4 more
doaj +1 more source
Effect of acid-reducing agents on clinical relapse in ulcerative colitis with pH-dependent-released 5-aminosalicylic acid: a multicenter retrospective study in Japan [PDF]
Background/Aims 5-Aminosalicylic acid (5-ASA) is a basic drug for inducing and maintaining remission for ulcerative colitis. One of its formulations has a coating with a pH-dependent degradation that ensures the release 5-ASA at the terminal ileum.
Yosuke Shimodaira +8 more
doaj +1 more source
The knowledge that 5-aminosalicylic acid (5-ASA) is the active compound of sulphasalazine and that it acts topically has stimulated the use of 5-ASA containing enemas and ocher similar compounds such as olsalazine and 4-aminosalicylic acid (4-ASA). 5-ASA
M. Campieri +6 more
doaj +1 more source
5-Aminosalicylic acid aggravates colitis mimicking exacerbation of ulcerative colitis [PDF]
Ulcerative colitis (UC) is one of the major clinical phenotypes of inflammatory bowel diseases. Although 5-aminosalicylic acid (5-ASA) is widely used for UC and its efficacy and safety have been demonstrated, a few patients paradoxically develop a severe
Jun Miyoshi +12 more
doaj +1 more source
Prospects of MMX Mesalazine in Routine Outpatient Treatment of Ulcerative Colitis
Aim. A general review of treatment approaches to ulcerative colitis (UC) and the importance of oral 5-aminosalicylic acid (5-ASA) for its routine outpatient management.Key points.
Yu. P. Uspenskiy +2 more
doaj +1 more source
Application of 5-Aminosalicylic Acid Preparations in the Treatment of Inflammatory Bowel Diseases
The article is devoted to the comparative characterization of different derivatives of 5-aminosalicylic acid. Researches of the past decades have changed the presentation of the potential use of aminosalicylates in the therapy of various inflammatory ...
Yu.M. Stepanov +2 more
doaj +1 more source
Diagnosis and outcome of oesophageal Crohn's disease [PDF]
BACKGROUND AND AIMS: Crohn's disease (CD) can involve any part of the gastrointestinal tract. We aimed to characterize clinical, endoscopic, histologic features and treatment outcomes of CD patients with oesophageal involvement.
Beaton, D +11 more
core +1 more source

