Results 131 to 140 of about 11,853,684 (309)

Trismus and Health‐Related Quality of Life in HNC Patients up to 10 Years Post‐Radiotherapy Completion

Head &Neck, EarlyView.
ABSTRACT Background This prospective study investigates trismus prevalence, quality of life (QOL), and trismus‐related symptoms in HNC patients up to 10 years post‐radiotherapy (RT). Methods A total of 211 patients with HNC receiving RT were followed pretreatment, 12, 60, and 120 months post‐RT.
Therese Karlsson, Lisa Tuomi, Caterina Finizia   +2 more
wiley   +1 more source

Cytotoxic Effects of Silibinin in Combination with 5-Fluorouracil on HT29 Colorectal Cancer Cells [PDF]

مجله علمی دانشگاه علوم پزشکی کردستان
Background and Aim: Colorectal cancer is one of the most common types of cancer in the world, causing many deaths worldwide each year. 5-Fluorouracil is the first choice for the treatment of this type of cancer.
Bahman Moradi Poodeh
doaj  

Clinical Translation of Patient‐Derived Organoids: Perspectives for Personalized Therapy in Cancer

International Journal of Cancer, EarlyView.
ABSTRACT Patient‐derived organoids (PDO) are accelerating precision medicine. These biological platforms allow for the autologous in vitro expansion of material from cancer patients in a considerably short period of time. These three‐dimensional models can faithfully recapitulate aspects of tissue heterogeneity, architecture, and relevant cellular ...
Haiyan Yue, Daniele Carchidi, Philipp Schmucker, Roland Seiler, Bernhard Kiss, Catarina Macedo‐Silva, Marianna Kruithof‐de Julio   +6 more
wiley   +1 more source

Chronotherapy with 5-Fluorouracil and Folinic Acid in Advanced Colorectal Carcinoma [PDF]

, 1994
Hallek, M., Emmerich, B., Lang, S., Langenmayer, Irmgard, Rump, W., Eibl-Eibesfeldt, B., Adler, S.   +6 more
core   +1 more source

Longitudinal Associations of Oxaliplatin Treatment With Chemotherapy‐Induced Peripheral Neuropathy in Colorectal cancer Survivors up to 2 Years Post‐Treatment

International Journal of Cancer, EarlyView.
ABSTRACT Chemotherapy‐induced peripheral neuropathy (CIPN) is a potentially long‐term consequence of oxaliplatin‐based chemotherapy for colorectal cancer (CRC). Oxaliplatin dosing is based on body surface area (BSA), but lean body mass (LBM) may influence susceptibility to long‐term CIPN.
Nadira R. Querido, Martijn J. L. Bours, Liselot Valkenburg‐van Iersel, Antoinetta J. M. Beijers, Stephanie O. Breukink, Maryska L. G. Janssen‐Heijnen, Eric T. P. Keulen, Joop L. M. Konsten, Judith de Vos‐Geelen, Matty P. Weijenberg, Colinda C. J. M. Simons   +10 more
wiley   +1 more source

The antiangiogenic properties of sulfated β-cyclodextrins in anticancer formulations incorporating 5-fluorouracil

, 2013
Sulfated β-cyclodextrins (S-β-CDs) are useful excipients for improving the solubility of drugs. One such formulation incorporating 5-fluorouracil (5-FU), termed FD(S), showed improved efficacy over 5-FU alone in orthotopic carcinoma xenograft models. S-β-
Marie Ranson (19586413), Anna Bezos (678524), Christopher R Parish (20212950), Clare Watson (20126469), Julie Locke (20117169), Kara Perrow (19585660)   +5 more
core   +1 more source

Perioperative Avelumab and Chemotherapy for Gastroesophageal Adenocarcinoma: Long‐Term Survival Outcomes

International Journal of Cancer, EarlyView.
ABSTRACT Long‐term survival data for patients with locally advanced gastro‐esophageal adenocarcinoma (GEA) treated with neoadjuvant chemoimmunotherapy are lacking. We describe the long‐term disease‐free survival (DFS) and overall survival (OS) outcomes of such patients treated with a novel neoadjuvant chemoimmunotherapy regimen, aDCF (avelumab with ...
Thierry Alcindor, James Tankel, Pierre‐Olivier Fiset, Mehrnoush Dehghani, Nicholas Bertos, Carmen Mueller, Jonathan Cools‐Lartigue, Sophie Camilleri‐Broet, Lorenzo Ferri   +8 more
wiley   +1 more source

Concomitant Use of Proton Pump Inhibitors and Survival Outcomes in Patients Receiving Adjuvant Chemotherapy for Stage III Colon Cancer

International Journal of Cancer, EarlyView.
ABSTRACT Proton pump inhibitors (PPIs) are commonly prescribed in patients with cancer. Prior studies suggest concomitant PPI use may reduce the efficacy of oral capecitabine through impaired absorption, with no interaction expected with intravenous 5‐fluorouracil (5‐FU). Using the Australian Comprehensive Cancer Outcomes and Research Database (ACCORD),
Matthew Loft, Vinoja Ganeshanathan, Rachel Wong, Shehara Mendis, Matthew Croxford, Ian T. Jones, Grace Gard, Sue‐Anne McLachlan, Jeanne Tie, Lucy Gately, Peter Gibbs   +10 more
wiley   +1 more source

Andrographolide enhanced 5-fluorouracil-induced antitumor effect in colorectal cancer via inhibition of c-MET pathway

, 2017
Meng Su,1 Baoli Qin,1 Fang Liu,2 Yuze Chen,2 Rui Zhang2 1Department of Internal Medicine, 2Department of Colorectal Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Liaoning, China Abstract: Colorectal ...
Su M, Chen Y, Zhang R, Qin B, Liu F
core  

Longitudinal AMH trajectories, ovarian reserve recovery, and fertility outcomes after multiagent chemotherapy for high‐risk gestational trophoblastic neoplasia: A real‐world cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To characterize anti‐Müllerian hormone (AMH) recovery after multiagent chemotherapy for high‐risk gestational trophoblastic neoplasia (GTN) and evaluate the impact of regimen and hysterectomy. Methods This was a retrospective cohort of 68 high‐risk GTN patients treated with EMA/CO (etoposide, methotrexate, actinomycin D ...
Wei Xue, Tianyi Chen, Yuxiao Wu, Tong Ren, Jun Zhao, Fengzhi Feng, Xirun Wan, Yang Xiang, Junjun Yang   +8 more
wiley   +1 more source