Results 151 to 160 of about 175,639 (315)

Enhancement of immune checkpoint inhibitor efficacy by DHX58+ SELL+ T cells in advanced gastric cancer

VIEW, EarlyView.
We created a coculture system using patient‐derived organoids (PDOs) and tumor‐infiltrating lymphocytes (TILs) that mimics important interactions between PDOs and TILs in the presence of various ICIs. Our findings reveal that CD62L+ T cells, activated by CD44+ cancer stem cells (CSCs), facilitate tumor regression in samples sensitive to ICIs, which is ...
Jie Chen, Youdong Liu, Hongda Pan, Tianyi Cai, Mingde Zang, Xiaowen Liu, Ziwen Long, Xin Fan, Jun Lu, Fenglin Liu   +9 more
wiley   +1 more source

Clinical Evidence for Three Distinct Gastric Cancer Subtypes: Time for a New Approach [PDF]

, 2013
Bearzi Italo, Bianconi Maristella, Bittoni Alessandro, Cascinu Stefano, Cecchini Luca, Del Prete Michela, Faloppi Luca, Giampieri Riccardo, Mandolesi Alessandra, Pistelli Mirco, SCARTOZZI, MARIO   +10 more
core   +1 more source

Finding ferritin footprints in 5-fluorouracil-induced cardiotoxicity. [PDF]

Cardiooncology
Ferri GM, Urina-Jassir M, Stanisic AV, Hensien JM, Lee G, Sullivan N, Siddiqi OK.   +6 more
europepmc   +1 more source

Hyperammonemic encephalopathy after 5-fluorouracil chemotherapy. [PDF]

CMAJ
Salimi P, Soriano A, Crocker E, Goldenberg B.   +3 more
europepmc   +1 more source

Open Versus Hybrid and Total Minimally Invasive Transthoracic Ivor Lewis Esophagectomy Following Neoadjuvant FLOT Chemotherapy: An Australian and New Zealand Cohort Study

World Journal of Surgery, EarlyView.
Retrospective analysis of transthoracic oesophagectomies undertaken between 2017 and 2022 following neoadjuvant FLOT chemotherapy from 22 ANZ centers. The primary endpoint was the rate of major (Clavien‐Dindo grade ≥ 3) postoperative complication.
Brendan Desmond, Maneesha De Silva, Darren J. Wong, David I. Watson, Cuong P. Duong, Tim Bright, Ahmad Aly, Margaret Lee, Kevin Chan, Garett Smith, David L. Chan, Neil Merrett, Sivakumar Gananadha, Yick Ho Lam, Harsh Kanhere, Mark Smithers, Michael Bozin, Matthew Read, Krinal Mori, Mary‐Ann Johnson, Enoch Wong, Sarah A. Martin, Geraldine Ooi, Yahya Al‐Habbal, Chon Hann Liew, Robert Bohmer, Jurstine Daruwalla, Mo Ballal, Rukshan Ranjan, Andrew D. MacCormick, Sharon Pattison, Nicholas Evennett, Jason Robertson, James Tan, Alexandra Gordon, Simon Bann, David S. Liu, SPACE‐FLOT ANZ Investigators   +37 more
wiley   +1 more source

Isoquercitrin Alleviates 5-Fluorouracil-Induced Intestinal Mucositis in Mice by Modulating Inflammation and Oxidative Stress. [PDF]

Chem Biodivers
Fideles LS, Campelo MDS, Neto JFC, Martins CDS, Barreto JEF, Vieira ÍGP, Ricardo NMPS, Cerqueira GS, Ribeiro MENP.   +8 more
europepmc   +1 more source

Impact of Metformin and Diabetes on Tumor Response to Total Neoadjuvant Therapy in Advanced Rectal Cancer: A Multicenter Retrospective Cohort Study

Asia-Pacific Journal of Clinical Oncology, EarlyView.
In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski, Mahima Raju, Tracy Fitzsimmons, Ishraq Murshed, Timothy J. Price, Michael Penniment, Sudarsha Selva‐Nayagam, Tarik Sammour   +7 more
wiley   +1 more source

Targeting EHMT2 overcomes 5-fluorouracil resistance in colorectal cancer by modulating cell cycle and apoptosis. [PDF]

Signal Transduct Target Ther
Tae IH, Kang Y, Lee J, Lee JM, Kim J, Lee SG, Park K, Ryu TY, Kim K, Kim G, Son T, Lee HW, Kim S, Lee HJ, Jung CR, Lim JH, Lee MS, Hur K, Han TS, Kim DS, Son MY, Cho HS.   +21 more
europepmc   +1 more source

Palbociclib in the Treatment of HR+/ HER2‐ Advanced or Metastatic Breast Cancer in Australia: A Real‐World Retrospective Analysis

Asia-Pacific Journal of Clinical Oncology, EarlyView.
This study investigated the real‐world use of CDK4/6 inhibitors in Australian patients with HR+/HER2‐ advanced or metastatic breast cancer, providing data on patient demographics, treatment patterns, and outcomes with palbociclib. ABSTRACT Background There is limited real‐world data on the use of CDK4/6 inhibitors in Australian patients with HR+/HER2 ...
Louise Nott, Eugene Moylan, Maree Colosimo, Giles Stratton, Thomas Chiu, Mahsa H. Kouhkamari, Maureen Hitschfeld, Jessica Michie, Richard De Boer   +8 more
wiley   +1 more source

Combinatorial effect of epirubicin and 5-fluorouracil in the treatment of temozolomide-resistant glioblastoma cells. [PDF]

Turk J Biol
Bayat M, Akman M, Kiliç T, Avşar T.
europepmc   +1 more source