Results 161 to 170 of about 175,639 (315)

Two Decades of Multimodal Management of Colorectal Liver Metastases With Long‐Term Outcomes

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background The management of patients with colorectal liver metastases (CRLM) is complex and requires a tailored approach based on disease extent, patient age, and comorbidities. Given the heterogeneity in presentation and evolving treatment algorithms, prognostic factors for long‐term survival following liver resection are contested.
Ali Mohtashami, Prajwol Shrestha, Sharon Chen, Jean‐Luc Vrisakis, Nazim Bhimani, Nick Pavlakis, Stephen J. Clarke, Connie I. Diakos, Matthew Wong, Thomas J. Hugh   +9 more
wiley   +1 more source

Localized nasal porokeratosis successfully treated with 5-fluorouracil and calcipotriene. [PDF]

JAAD Case Rep
Rashidi A, Dastgheib M, Kamyab K, Saedpanah R, Firooz A.   +4 more
europepmc   +1 more source

Efficacy and Safety of Anal High‐Grade Squamous Intraepithelial Lesion Treatment Modalities: A Systematic Review

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background There is compelling evidence that treating high‐grade squamous intraepithelial lesions (HSIL), the anal squamous cell cancer (ASCC) precursor, reduces the risk of developing ASCC. Using high‐resolution anoscopy (HRA), surgical excision, ablative and topical therapies are widely used to treat HSIL.
Matthew Joseph Marino, Sophie Jones, Nicholas Reid Caldwell, Catherine Cartwright, Benedict Blacket, Richard Clive Turner   +5 more
wiley   +1 more source

The beneficial effects of leave extract of Commiphora leptophloeos on intestinal mucositis induced by 5-fluorouracil in mice. [PDF]

Acta Cir Bras
Silva ASD, Barbosa SJA, Ribeiro SB, Carvalho LVS, Silva RTDD, Guerra GCB, Araújo Júnior RF, Silva NCD, Andrade RVS, Paiva GM, Langassner SMZ, Dantas-Medeiros R, Fé RASS, Lima MLS, Araújo AA.   +14 more
europepmc   +1 more source

The efficacy and safety of reducing intraocular pressure to single‐digit levels in Normal‐tension glaucoma: A systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract Purpose This systematic review and meta‐analysis aim to evaluate the efficacy and safety of further lowering intraocular pressure (IOP) to single‐digit levels in treated patients with progressive normal‐tension glaucoma (NTG). Methods A literature search was conducted in MEDLINE (via PubMed), Scopus and Web of Science. We selected studies that
Beatriz Araújo‐Azevedo, Renato Ferreira‐da‐Silva, João Barbosa‐Breda   +2 more
wiley   +1 more source

Effect of 5-Fluorouracil on liver regeneration and metabolism after partial hepatectomy in rat

The Turkish Journal of Gastroenterology, 2001
Hakan M. KÖKSAL, Levent ERDEM, Sadık YILDIRIM, Turgut İPEK, Işıl PAKİŞ   +4 more
doaj  

Factors influencing pharmacokinetics of 5-fluorouracil in cancer patients: a systematic review of population pharmacokinetic models. [PDF]

Eur J Clin Pharmacol
Suthahar T, Veerabhadrappa J, Munshi R, Anbu Raj E, Gota V, Ivaturi V, Mallayasamy S.   +6 more
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Brain-heart: first case report of simultaneous toxicity of 5-fluorouracil. [PDF]

Rep Pract Oncol Radiother
Solórzano VEU, Herrera EPA, Granda DJP, Moreira-Vera DV, Soria TEA, Rodríguez LEF.   +5 more
europepmc   +1 more source

Aspartate Transporter SLC1A3 Promotes Colorectal Cancer via MDM2‐p53 Pathway and M2 Macrophage Polarization

Cancer Science, EarlyView.
SLC1A3 promotes colorectal cancer progression by transporting extracellular aspartate into tumor cells, thereby activating the PKC/MDM2/p53 pathway to enhance proliferation. Reduced extracellular aspartate, combined with p53‐dependent suppression of CSF2 and IL17C, drives M2 macrophage polarization via immune modulation, macrophage recruitment, and M2 ...
Chao Deng, You Zhou, Sijie Song, Hongtao Liu, Siqi Liao, Li Zhou, Siyuan Chen, Zhihang Zhou, Song He, Bingrong Liu   +9 more
wiley   +1 more source