Results 61 to 70 of about 16,556 (226)

Hepatic fibrogenesis requires sympathetic neurotransmitters [PDF]

, 2004
Background and aims: Hepatic stellate cells (HSC) are activated by liver injury to become proliferative fibrogenic myofibroblasts. This process may be regulated by the sympathetic nervous system (SNS) but the mechanisms involved are unclear.
Diehl, AM, Huang, J, Li, Z, Lin, H, Moran, TH, Oben, JA, Roskams, T, Sinelli, N, Smedh, U, Thomas, SA, Torbenson, M, Yang, S   +11 more
core   +2 more sources

Altered Dopamine Metabolism and Response to Treatment with Levodopa/Carbidopa in MCT8 Deficiency

Movement Disorders, EarlyView.
Abstract Background Allan‐Herndon‐Dudley syndrome (AHDS)/monocarboxylate transporter 8 (MCT8) deficiency is a rare X‐linked encephalopathy caused by SLC16A2 variants, impairing thyroid hormone (TH) transport into the brain. This leads to early central nervous system (CNS) TH deficiency, affecting brain maturation.
Fabio Bruschi, Ylenia Vaia, Clara E. Antonello, Marco Spada, Francesco Porta, Cristina Marinaccio, Claudia Carducci, Thomas Opladen, Jacopo Sartorelli, Federica Maria Zibordi, Daniele Ghezzi, Francesco Nicita, Davide Tonduti   +12 more
wiley   +1 more source

Influence of fetal tissues transplantation on the brain serotoninergic systems in experimental animals after traumatic brain injury

Ukrainian Neurosurgical Journal, 2012
Introduction. Taking into consideration the high frequency of complications after severe traumatic brain injury (STBI), caused mainly by different brain neuromediator systems integrative disfunctions, a search of methods for their correction ...
Boris Baranenko, Vitaliy Tsymbaliuk, Irina Vasileva, Nataliya Chopik   +3 more
doaj   +1 more source

Smoking-induced long-lasting modifications of human platelet serotonin catabolism through a MAO epigenetic regulation [PDF]

, 2008
Postulating that serotonin, secreted from smoking-activated platelets, could be involved in smoking-induced vascular modifications, we studied 115 men distributed in smokers (S), former smokers (FS) and never smokers (NS).
Alain Simon, Francine Rendu, Gilles Chironi, Jacques Callebert, Jacques Mallet, Jean-Louis Mé, Jean-Marie Launay, Katell Peoc', Muriel Del Pino   +8 more
core   +1 more source

Individual differences in impulsive and risky choice: effects of environmental rearing conditions [PDF]

, 2014
The present experiment investigated early-rearing environment modulation of individual differences in impulsive and risky choice. Rats were reared in an isolated condition (IC; n = 12), in which they lived alone without novel stimuli, or an enriched ...
Kirkpatrick, Kimberly, Koci, Juraj, Marshall, Andrew T., Park, Yoonseong, Smith, Aaron P.   +4 more
core   +1 more source

Effect of Social Rank on Gut Microbes and Their Metabolites of Greater Long‐Tailed Hamsters (Tscherskia triton)

Integrative Zoology, EarlyView.
Social rank in greater long‐tailed hamsters (Tscherskia triton) shapes gut microbiota composition and metabolite profiles. Dominant males exhibit a “high‐vigilance, metabolically activated” phenotype, with elevated aggression and specific gut microbiota enriched in energy‐harvesting taxa and fecal queuine.
Da Zhang, Xiaoming Xu, Zhibin Zhang
wiley   +1 more source

A Comparative Study on Neurochemistry of Cerebrospinal Fluid in Advanced Parkinson's Disease

Neurobiology of Disease, 1999
This study addresses two issues: (1) the comparative neurochemistry of classic tremor type of Parkinson's disease or PD-A and akinetic type of Parkinson's disease or PD-B; and (2) the neurochemistry of levodopa failure syndrome (LDFS).
H. Liu, R.P. Iacono, T. Schoonenberg, S. Kuniyoshi, J. Buchholz   +4 more
doaj   +1 more source

Quantificação do ácido 5-hidroxi-indolacético urinário por técnica caseira do nitrosonaftol comparada com ensaio de nitrosonaftol em microcoluna de cromatografia e imunoensaio enzimático [PDF]

, 2014
The aim of this study was to compare the colorimetric kit and enzyme-linked immunosorbent assay (ELISA) methods to quantify urinary 5-hydroxyindoleacetic acid through the Goldenberg's technique, exploring the potential of replacing it.
Carrilho, Flair José, Colaúto, Carlos, Mattar, Rejane, Silva, Joyce Matie Kinoshita Da   +3 more
core   +3 more sources

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, Volume 16, Issue 1, Page 52-67, January 2026.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Neuropeptide Y and Calcitonin Gene-Related Peptide in Cerebrospinal Fluid in Parkinson’s Disease with Comorbid Depression versus Patients with Major Depressive Disorder

Frontiers in Psychiatry, 2017
Parkinson’s disease (PD) is the second most common neurodegenerative disease in the world. The diagnosis of PD is based on movement dysfunctions. Many patients also suffer from comorbid depression in spite of adequate treatment with dopamine replacement,
Per Svenningsson, Sven Pålhagen, Aleksander A. Mathé   +2 more
doaj   +1 more source