Results 71 to 80 of about 16,556 (226)

Glioma induced alterations in fecal short-chain fatty acids and neurotransmitters

CNS Oncology, 2020
Aim: To explore fecal short-chain fatty acids and neurotransmitter alterations in a mouse–glioma model and glioma patients. Methods: Liquid chromatography–mass spectrometry and 16S rRNA-sequencing from fecal samples were performed to measure metabolite ...
Antonio Dono, Anthony Patrizz, Ryan M McCormack, Nagireddy Putluri, Bhanu P Ganesh, Balveen Kaur, Louise D McCullough, Leomar Y Ballester, Yoshua Esquenazi   +8 more
doaj   +1 more source

Exploring the aging process of cognitively healthy adults by analyzing cerebrospinal fluid metabolomics using liquid chromatography-tandem mass spectrometry

BMC Geriatrics, 2023
Background During biological aging, significant metabolic dysregulation in the central nervous system may lead to cognitive decline and neurodegeneration. However, the metabolomics of the aging process in cerebrospinal fluid (CSF) has not been thoroughly
Fu-Chao Liu, Mei-Ling Cheng, Chi-Jen Lo, Wen-Chuin Hsu, Gigin Lin, Huan-Tang Lin   +5 more
doaj   +1 more source

Role of aggressivity on reactivity and craving before and after cue exposure in recently detoxified alcoholics: Results from an experimental study [PDF]

, 2001
The role of aggressivity and cue exposure in induction of craving were investigated in a clinical setting. Thirty abstinent alcoholic patients were divided into a low and a high aggressive group based on scores on the physical aggression subscale of the ...
Chiang, Sonnig S. W., Schütz, Christian G., Soyka, Michael   +2 more
core   +1 more source

Microfabricated Neural Biosensors for Detection of Neurotransmitters, Biomarkers, and Small Molecules: Emerging Trends on Self‐Sustained Systems and Energy Harvesting

Advanced Sensor Research, Volume 5, Issue 1, January 2026.
This paper reviews the state of the art and recent developments in thin‐film biosensors for the detection of neurotransmitters, small molecules, and biomarkers within flexible, implantable bioelectronic systems. It covers the main sensing modalities, including electrochemical, plasmonic, acoustic, and magnetic, alongside their materials, transduction ...
Massimo Mariello
wiley   +1 more source

Pitolisant Inhibits Alcohol Drinking and Improves Withdrawal Negative Affect Through Lateral Habenula Histaminergic Signaling in Mice

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Pitolisant, an FDA‐approved H3R antagonist, counteracts the rewarding and sedative effects of ethanol, reduces alcohol intake, and alleviates the negative affect during withdrawal. This might occur via the antagonism of presynaptic autoreceptors and heteroreceptors H3Rs in the lateral habenula, thereby activating the H2R/p‐CREB/BDNF signaling and ...
Yan Zhao, Yixin Fu, Tianhao Liu, Zanhao Yang, Zhengzhong Yang, Bingqing Chen, Lipeng Zhou, Juntao Yang, Duo Chen, Xiaojiao Han, Ying Tang, Jiang‐Hong Ye, Chao‐Yu Miao, Rao Fu   +13 more
wiley   +1 more source

Tryptophan metabolites predict response after cognitive behavioral therapy for depression: A single-arm trial.

Journal of Affective Disorders Reports, 2023
Background: Cognitive behavioral therapy (CBT) is one of the most prominent standard treatments for depression. However, like with antidepressant drugs, a subgroup of patients remains unresponsive.
Maria S Simon, Elif Weidinger, Bianka Burger, Yasemin Kisla, Julia Niedeggen, Petra Thaler, Michael Zaudig, Ulrich Voderholzer, Markus Schwarz, Norbert Müller   +9 more
doaj   +1 more source

B-206 The Determination of Vanillylmandelic Acid (VMA), Homovanillic Acid (HVA) and 5-Hydroxyindolacetic Acid (5-HIAA) by LC-Ms/MS Assay in Urine Samples for Diagnosis of Neuroendocrynes Tumors [PDF]

, 2023
Lovaco Castellano F, B F Paulo, Danielle Alves Gomes Zauli   +2 more
openalex   +1 more source

Preliminary Evidence That High-Dose Vitamin C has a Vascular Disrupting Action in Mice [PDF]

, 2014
High intravenous doses of vitamin C (ascorbic acid) have been reported to benefit cancer patients but the data are controversial and there is incomplete knowledge of what physiological mechanisms might be involved in any response.
Bruce C. Baguley, Emma Richardson, Qi Ding   +2 more
core   +2 more sources

Chinese Yam (Dioscorea) Improves Psychiatric Comorbidities of Colitis Mice Through Regulating 5‐HT Metabolism

Food Frontiers, Volume 7, Issue 1, January 2026.
CY alleviates colitis and associated neuropsychiatric symptoms by reducing serum LPS, restoring intestinal barrier integrity, and modulating serotonin metabolism. It inhibits neuroinflammation, improves synaptic function, and normalizes HPA axis hyperactivity via downregulation of HTR2C, offering a multi‐targeted strategy for gut–brain axis dysfunction
Yifan Cui, Yingzhuo Zhou, Xiaoying Zhang, Yinghua Luo, Chen Ma, Li Dong, Xiaosong Hu, Daotong Li, Lin Wang, Fang Chen   +9 more
wiley   +1 more source

Association Between the Dutch Mediterranean‐Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND‐NL) Diet Adherence and Systemic Tryptophan Metabolites in Older Adults at Risk of Cognitive Decline: An Exploratory Study

Molecular Nutrition &Food Research, Volume 70, Issue 1, January 2026.
Following the MIND diet may support brain health in older adults at risk of cognitive decline by influencing tryptophan (TRP) metabolism. Plasma samples and dietary intake data from the HELI intervention trial were used. Bivariate latent change score modeling analysis showed that greater adherence to the MIND diet was linked to higher tryptophan levels,
Sonja Beers, Lisette C. P. G. M. de Groot, Mark R. van Loenen, Lianne B. Remie, Mechteld Grootte Bromhaar, Andrea Anesi, Urska Vrhovsek, Joukje M. Oosterman, Esther Aarts, Mara P. H. van Trijp, Yannick Vermeiren   +10 more
wiley   +1 more source