Results 71 to 80 of about 344,978 (286)

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker, Abhijit Das, Andres Jimenez, Areeba Basit, Yike Jiang, Emily A. Smitherman, Heather Van Mater, Taylor Howard, Alexander J. Sandweiss, Kristen S. Fisher   +9 more
wiley   +1 more source

Serotonergic Modulation of Locomotor Activity From Basal Vertebrates to Mammals

Frontiers in Neural Circuits, 2020
During the last 50 years, the serotonergic (5-HT) system was reported to exert a complex modulation of locomotor activity. Here, we focus on two key factors that likely contribute to such complexity. First, locomotion is modulated directly and indirectly
Aurélie Flaive, Maxime Fougère, Cornelis Immanuel van der Zouwen, Dimitri Ryczko, Dimitri Ryczko, Dimitri Ryczko, Dimitri Ryczko   +6 more
doaj   +1 more source

Evaluation of responses to 5-HT-enhancing drugs in NMRI mice [PDF]

, 2015
In humans, the ingestion of the combination of two or more serotonin (5-HT)-enhancing drugs but also of a single drug in overdose can induce serious adverse effects, which are characteristics of the serotonin syndrome (SS).
Bert, Bettina, Fink, Heidrun, Haberzettl, Robert   +2 more
core   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Serotonin (5‐Hydroxytryptamine): Metabolism, Signaling, Biological Functions, Diseases, and Emerging Therapeutic Opportunities

MedComm
Serotonin (5‐hydroxytryptamine; 5‐HT) is an evolutionarily conserved monoamine neurotransmitter that plays critical roles in various physiological systems, functioning as a neurotransmitter, hormone, and paracrine signaling molecule.
Yuxin Zhang, Nan Wang, Louqian Zhang, Yan Zhuang, Qilei Xin, Xiaosong Gu, Chunping Jiang, Junhua Wu   +7 more
doaj   +1 more source

Brain Monoamine Asymmetry in Chicks Subjected to a Separation-Stress Procedure with Litter Substrate

The Journal of Poultry Science, 2015
Activation of the right hemispheric neurotransmitter systems is related to negative emotion and stress in mammals, but this relationship is not fully known in birds. The effect of the presence of sawdust litter on behavior and brain monoamine laterality
Takashi Bungo, Eriko Nakasai, Minami Takawaki, Hiroshi Tanizawa, Shin-Ichi Kawakami   +4 more
doaj   +1 more source

Post Natal Impact of Maternal Tryptophan Deficiency on Central CO2/PH Chemosensitivity [PDF]

, 2012
Cells and mechanisms underlying central chemosensitivity, are poorly understood and can be controversial. Our overarching hypothesis is that brainstem 5-HT and/or GABA neurons contribute to detection and response to changes in pH/CO2. Our experiments are
Mosher, Bryan P.
core  

Serotonin mediated changes in corticotropin releasing factor mRNA expression and feeding behavior isolated to the hypothalamic paraventricular nuclei [PDF]

, 2011
Fenfluramine reduces hunger and promotes body weight loss by increasing central serotonin (5-HT) signaling. More recently, neuropeptides have been linked to the regulation of feeding behavior, metabolism and body weight.
Boisvert, Joanne P, Boschuetz, Tyler J., Choi, Sujean, Mueller, Christopher R, Resch, Jon M   +4 more
core   +2 more sources