Results 141 to 150 of about 78,996,387 (176)

5-HT1A receptor ligands

1997
Publisher Summary For 5-HT1A receptors, many potent and selective ligands belonging to different chemical classes such as aminotetralins, indolylalkylamines, ergolines, aporphines, arylpiperazines, and aryloxyalkylamines are available. The majority of these compounds are agonists or partial agonists.
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Differential induction of 5-HT1A-mediated responses in vivo by three chemically dissimilar 5-HT1A agonists.

The Journal of Pharmacology and Experimental Therapeutics, 1994
In the rat, activation of 5-hydroxytryptamine1A (5-HT1A) receptors causes hypothermia and the 5-HT syndrome. The effects of three chemically dissimilar 5-HT1A agonists administered s.c. [8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT), gepirone, and (+)4-[n-5-(methoxychroman-3-yl)n-propylamino]butyl-8-azaspiro++ +[4,5] decane-7,adione ((+) S-20499)]
P A, Scott, J M, Chou, H, Tang, A, Frazer   +3 more
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5-HT1A receptors and alcohol preference

European Neuropsychopharmacology, 1993
Abstract Microinjection and lesion studies support the involvement of presynaptic 5-HT1A receptors in the reduction of ethanol (EtOH) intake induced by the selective 5-HT1A receptor agonists 8-OH-DPAT and ipsapirone in selectively bred Wistar rats, with high preference for EtOH over water in a two-bottle free choice situation.
J. De Vry, R. Schreiber, R. de Beun, K. Opitz   +3 more
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[The functional change in the 5-HT1A receptor induced by stress and the role of the 5-HT1A receptor in neuroprotection].

Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2005
Mice exposed to various stresses, especially restrained-stress, revealed the anxiogenic effect detected by the light-dark test. Under this condition, a remarkable decrease in [35S]GTPgammaS binding to membranes from the prefrontal cortex, amygdala and hypothalamus of restrained-stress mice stimulated by the selective 5-HT1A receptor agonist 5 ...
Minoru, Narita, Kazuya, Miyagawa, Michiko, Narita, Keisuke, Mizuo, Mayumi, Miyatake, Suzuki, Tsutomu   +5 more
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5-HT1A Partial Agonists

Drugs, 1991
D A, Glitz, R, Pohl
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5-HT1A Receptor

2010
Michael H. Bloch, Michael H. Bloch, Mark A. Geyer, David C. S. Roberts, Eileen M. Joyce, Jonathan P. Roiser, John H. Halpern, Joji Suzuki, Pedro E. Huertas, Torsten Passie, John H. Halpern, Joji Suzuki, Pedro E. Huertas, Torsten Passie, Joji Suzuki, Torsten Passie, Pedro E. Huertas, John H. Halpern, Joji Suzuki, Torsten Passie, Pedro E. Huertas, John H. Halpern, David E. Nichols, Marie-Louise G. Wadenberg, Trevor W. Robbins, David S. Baldwin, Sophie Tambour, John C. Crabbe, Lucio Tremolizzo, Gessica Sala, Carlo Ferrarese, Brian L. Odlaug, Jon E. Grant, Paul D. Callaghan, Iain S. McGregor, Murray R. Thompson, Sarah Morgan, Angus Mackay, E. Ernst, Lawrence H. Price, Michael M. Morgan, MacDonald J. Christie, Susan Jones, Andrew Young, Elizabeth C. Warburton, Stephen J. Hill, Anthony R. Isles, Lawrence S. Wilkinson, Subhash C. Pandey, Subhash C. Pandey, Subhash C. Pandey, Aldo Badiani, James Winslow, Susan Jones, Jill B. Becker, Lucio Tremolizzo, Gessica Sala, Carlo Ferrarese, Paul D. Callaghan, Iain S. McGregor, Murray R. Thompson, David E. Nichols, Jason C. G. Halford, Stephen B. Dunnett, Martine Cador, Naheed (Max) Mirza, Andrea Bari, Yesne Alici, William Breitbart, Andrea Bari, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, Jason C. G. Halford, Ennio Esposito, William Invernizzi, Gary Remington, Tomasz Schneider, Michel Billiard, Michel Billiard, Alyson J. Bond, Paolo Nencini, Michele S. Milella, Brian E. Leonard, Yesne Alici, William Breitbart, Luis de Lecea, Michel Billiard, Samuel B. Hutton, Jason C. G. Halford, R. H. De Rijk, E. R. de Kloet, Tooru M. Mizuno, Maria Isabel Colado, A. Richard Green   +94 more
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[Presynaptic 5-HT1A receptors in immunomodulation].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2007
It is shown that a selective agonist of 5-HT1A receptors 8-OH-DPAT in a low dose (0.1 mg/kg), which is known to affect mainly the presynaptic 5-HT1A receptors increased the immune response at the peak of reactions (the forth or fifth day after immunization with sheep red blood cells - SRBC) in CBA mice and Wistar rats. Treatment of the animals with the
S M, Davydova, G V, Idova
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Validation and Reproducibility of Measurement of 5-HT1A Receptor Parameters With [Carbonyl-11C]WAY-100635 in Humans: Comparison of Arterial and Reference Tissue Input Functions

Journal of Cerebral Blood Flow and Metabolism, 2000
J John Mann, Anissa Abi-Dargham, Mark Slifstein   +2 more
exaly  

Cannabidiol and 5-HT1A Receptors

2016
Manoela V. Fogaça, Alline C. Campos, Francisco S. Guimarães   +2 more
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5-HT1A Receptor Activation Contributes to Ziprasidone-Induced Dopamine Release in the Rat Prefrontal Cortex

Biological Psychiatry, 2000
Jeffrey Sprouse, Stevin H Zorn, Anne W Schmidt   +2 more
exaly