Results 261 to 270 of about 284,594 (312)

Translating 5-HT receptor pharmacology.

Neurogastroenterology and motility, 2010
Since metoclopramide was first described (in 1964) there have been several attempts to develop compounds which retained gastrointestinal prokinetic activity (via 5-HT(4) receptor activation) but without the limiting side effects associated with dopamine D(2) receptor antagonism.
openaire   +2 more sources

MDP and 5-HT receptors. Does MDP interact with 5-HT(7) receptors?

International journal of immunopharmacology, 2000
A possible interaction of immunomodulator muramyl dipeptide (MDP) with 5-HT(7) (5-hydroxytryptamine) receptors was investigated. The activation of 5-HT(7) receptors relaxes the guinea-pig distal ileum. The whole ileum segments were, therefore, cut and placed into the bath.
J, Sevcík, V, Rûzicka, J, Slánský, K, Masek   +3 more
openaire   +1 more source

Neuronal 5-HT receptors in the periphery

Neuropharmacology, 1984
5-Hydroxytryptamine (5-HT) induces responses in neurones from all branches of the mammalian peripheral nervous system. Responses may be excitatory or inhibitory and are mediated through at least four distinct receptor sites. One receptor mediates excitation in motoneurones and preganglionic sympathetic neurones and can be designated a D (or possibly 5 ...
openaire   +2 more sources

5-HT Receptors

2020
Kerry Layne, Albert Ferro
openaire   +1 more source

Discriminating between 5-HT₃A and 5-HT₃AB receptors.

British journal of pharmacology, 2014
The 5-HT3B subunit was first cloned in 1999, and co-expression with the 5-HT3A subunit results in heteromeric 5-HT₃AB receptors that are functionally distinct from homomeric 5-HT₃A receptors. The affinities of competitive ligands at the two receptor subtypes are usually similar, but those of non-competitive antagonists that bind in the pore often ...
A J, Thompson, S C R, Lummis
openaire   +1 more source

Higher-End Serotonin Receptors:  5-HT₅, 5-HT₆, and 5-HT₇

Journal of Medicinal Chemistry, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +2 more sources

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-Vornhagen, Boris Böll, Peter Schellongowski   +2 more
exaly  

Chimeric antigen receptor T‐cell therapy in multiple myeloma: A comprehensive review of current data and implications for clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Rujul Parikh, Sagar Lonial
exaly  

5-HT receptors and migraine

1990
Migraine is a vascular headache but its pathophysiology is complex and multifactorial. Of the many pathophysiological factors that are implicated in migraine, changes in the metabolism of 5-hydroxytryptamine (5-HT) are the best documented. During the headache phase of migraine, urinary excretion of 5-hydroxyindoleacetic acid increases, whereas the ...
openaire   +1 more source