Results 11 to 20 of about 79,000,091 (170)

Japanese Cohort Study and Meta‐Analysis Demonstrate Significant Association Between Serotonin Transporter‐Linked Polymorphic Region and Schizophrenia

Neuropsychopharmacology Reports
Schizophrenia is a prevalent psychiatric disease that substantially affects health and increases mortality risk. The 5‐hydroxytryptamine system has been implicated in its pathogenesis.
Masao Miyachi, Toshiyuki Shirai, Shohei Okada, Kiriko Minami, Ryo Tsukamoto, Kentaro Mouri, Satoshi Okazaki, Ikuo Otsuka, Akitoyo Hishimoto   +8 more
doaj   +2 more sources

Japanese Cohort Study Identifies an Association Between the Serotonin Transporter–Linked Polymorphic Region and Suicide Death

Neuropsychopharmacology Reports
Introduction More than 720 000 individuals die by suicide annually worldwide, making it a major public health concern and a leading cause of death among young people, particularly in Asian populations.
Shohei Okada, Toshiyuki Shirai, Masao Miyachi, Gentaro Yamasaki, Kiriko Minami, Ryo Tsukamoto, Kentaro Mouri, Takaki Tanifuji, Ryuichi Katada, Satoshi Okazaki, Ikuo Otsuka, Akitoyo Hishimoto   +11 more
doaj   +2 more sources

Overnight retention of emotional memories is influenced by BDNF Val66Met but not 5-HTTLPR

, 2019
Emotional memory may be modulated by BDNF Val66Met and 5-HTTLPR polymorphisms. However, the influence of these genetic variants on the overnight retention of emotional memories has not been investigated in humans.
Jannus Harro (17223136), Marcus O Harrington (17223139), Kristel Klaus (224422), Mariliis Vaht (287114), Kyla Pennington (17165134), Simon Durrant (17157154)   +5 more
core   +4 more sources

“Out, out, brief candle! Life’s but a walking shadow”: 5-HTTLPR Is Associated With Current Suicidal Ideation but Not With Previous Suicide Attempts and Interacts With Recent Relationship Problems

Frontiers in Psychiatry, 2020
BackgroundSuicide is an unresolved psychiatric and public health emergency, claiming 800,000 lives each year, however, its neurobiological etiology is still not understood.
Janos Bokor, Sandor Krause, Dora Torok, Nora Eszlari, Nora Eszlari, Sara Sutori, Sara Sutori, Zsofia Gal, Peter Petschner, Peter Petschner, Ian M. Anderson, Bill Deakin, Gyorgy Bagdy, Gyorgy Bagdy, Gyorgy Bagdy, Gabriella Juhasz, Gabriella Juhasz, Gabriella Juhasz, Xenia Gonda, Xenia Gonda, Xenia Gonda   +20 more
doaj   +1 more source

The 5-HTTLPR variant in the serotonin transporter gene modifies degeneration of brain regions important for emotion in behavioral variant frontotemporal dementia

NeuroImage: Clinical, 2015
The serotonin transporter length polymorphism (5-HTTLPR) short allele (5-HTTLPR-s) has been associated with differential susceptibility for anxiety and depression in multiple psychiatric disorders.
Jennifer S. Yokoyama, Luke W. Bonham, Virginia E. Sturm, Babu Adhimoolam, Anna Karydas, Giovanni Coppola, Bruce L. Miller, Katherine P. Rankin   +7 more
doaj   +1 more source

Risk and protective effects of serotonin and BDNF genes on stress-related adult psychiatric symptoms

Neurobiology of Stress, 2019
We focused on individual risk by examining childhood adversity and current psychiatric symptoms in a sample of 100 college students genotyped for both the serotonin transporter (5-HTTLPR) and the brain-derived neurotrophic factor (BDNF).
Paul G. Nestor, Keira O'Donovan, Hannah E. Lapp, Victoria Choate Hasler, Sara B. Boodai, Richard Hunter   +5 more
doaj   +1 more source

Serotonin transporter genotype linked to adolescent substance use treatment outcome through externalizing behavior

Frontiers in Pediatrics, 2014
Meta-analyses suggest that the serotonin transporter linked polymorphic region (5-HTTLPR) short (S) allele, relative to the long (L) allele, is associated with risk for alcohol dependence, particularly among individuals with early onset antisocial ...
Tammy eChung, Jack eCornelius, Christopher Stephen Martin, Robert eFerrell, Stephen A. Maisto, Duncan B Clark   +5 more
doaj   +1 more source

Serotonin transporter gene-linked polymorphism affects detection of facial expressions. [PDF]

PLoS ONE, 2013
Previous studies have demonstrated that the serotonin transporter gene-linked polymorphic region (5-HTTLPR) affects the recognition of facial expressions and attention to them.
Ai Koizumi, Norimichi Kitagawa, Hirohito M Kondo, Miho S Kitamura, Takao Sato, Makio Kashino   +5 more
doaj   +1 more source

Variability in the effect of 5-HTTLPR on depression in a large European population: the role of age, symptom profile, type and intensity of life stressors. [PDF]

PLoS ONE, 2015
Although 5-HTTLPR has been shown to influence the risk of life stress-induced depression in the majority of studies, others have produced contradictory results, possibly due to weak effects and/or sample heterogeneity.In the present study we investigated
Gabriella Juhasz, Xenia Gonda, Gabor Hullam, Nora Eszlari, David Kovacs, Judit Lazary, Dorottya Pap, Peter Petschner, Rebecca Elliott, John Francis William Deakin, Ian Muir Anderson, Peter Antal, Klaus-Peter Lesch, Gyorgy Bagdy   +13 more
doaj   +1 more source

5-HTTLPR Genotype Moderates the Effects of Past Ecstasy Use on Verbal Memory Performance in Adolescent and Emerging Adults: A Pilot Study. [PDF]

PLoS ONE, 2015
Ecstasy use is associated with memory deficits. Serotonin transporter gene (5-HTTLPR) polymorphisms have been linked with memory function in healthy samples.
Natasha E Wright, Judith A Strong, Erika R Gilbart, Skyler G Shollenbarger, Krista M Lisdahl   +4 more
doaj   +1 more source