Updated Parkinson's disease motor subtypes classification and correlation to cerebrospinal homovanillic acid and 5-hydroxyindoleacetic acid levels [PDF]
Clinical Parkinsonism & Related Disorders, 2023 Introduction: Motor classifications of Parkinson's Disease (PD) have been widely used. This paper aims to update a subtype classification using the MDS-UPDRS-III and determine if cerebrospinal neurotransmitter profiles (HVA and 5-HIAA) differ between ...
Christopher Adams +6 more
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Impact of Plasma 5 Hydroxyindoleacetic Acid, a Serotonin Metabolite, on Clinical Severity in Acute Respiratory Distress Syndrome [PDF]
Frontiers in Medicine, 2021 Acute respiratory distress syndrome (ARDS) is characterized by dysregulated vascular permeability. The clinical outcomes remain poor, and the disease burden is widespread.
Takeshi Tanaka +5 more
doaj +4 more sources
Tryptophan Challenge in Healthy Controls and People with Schizophrenia: Acute Effects on Plasma Levels of Kynurenine, Kynurenic Acid and 5-Hydroxyindoleacetic Acid [PDF]
Pharmaceuticals, 2022 The pivotal tryptophan (TRP) metabolite kynurenine is converted to several neuroactive compounds, including kynurenic acid (KYNA), which is elevated in the brain and cerebrospinal fluid of people with schizophrenia (SZ) and may contribute to cognitive ...
Korrapati V. Sathyasaikumar +8 more
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5-Hydroxyindoleacetic acid, a new ligand for GPR35, plays an important role in inflammatory disease [PDF]
Acta Biochimica et Biophysica Sinica, 2022 Yang Zhisheng +3 more
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Serum 5-Hydroxyindoleacetic Acid and Ratio of 5-Hydroxyindoleacetic Acid to Serotonin as Metabolomics Indicators for Acute Oxidative Stress and Inflammation in Vancomycin-Associated Acute Kidney Injury [PDF]
Antioxidants, 2021 The incidence of vancomycin-associated acute kidney injury (VAKI) varies from 5–43%, and early detection of VAKI is important in deciding whether to discontinue nephrotoxic agents.
Hyun-Seung Lee +4 more
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Surgical Correction of Carcinoid Heart Disease Improves Liver Function and 5-Hydroxyindoleacetic Acid Levels [PDF]
Frontiers in Surgery, 2022 IntroductionCarcinoid heart disease (CHD) is a consequence of neuroendocrine tumors releasing 5-hydroxytryptamine (5-HT) into the systemic circulation, affecting right heart valves, causing fibrosis, and eventually right heart failure.
Husnain Abbas Shah +13 more
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5-Hydroxyindoleacetic acid as a biomarker for revealing perforation in acute appendicitis [PDF]
BMC GastroenterologyBackground The present study investigated the level of 5-hydroxyindoleacetic acid (5-HIAA) in perforated and nonperforated appendicitis patients. This issue is important for timely diagnosis of acute appendicitis complications and making decision about ...
Arash Mohammadi Tofigh +6 more
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Serum and plasma 5-hydroxyindoleacetic acid as an alternative to 24-h urine 5-hydroxyindoleacetic acid measurement [PDF]
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2015 Background Neuroendocrine tumours are slow growing tumours known to secrete a variety of vasoactive peptides which give rise to symptoms of the carcinoid syndrome. The diagnosis and monitoring of patients with neuroendocrine tumours is undertaken in many centres using 24 h urinary measurement of 5-hydroxyindoleacetic acid.
Jo Adaway +7 more
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Decreased homovanillic acid and 5‐hydroxyindoleacetic acid levels in the cerebrospinal fluid of patients with Dravet syndrome with parkinsonism [PDF]
Epilepsia OpenDravet syndrome (DS) is an early onset, developmental, and epileptic encephalopathy characterized by drug‐resistant seizures and multiple comorbidities.
Ryo Sugiyama +5 more
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The effect of dietary tryptophan supplementation, and an oral tryptophan challenge, on urinary excretion of 5-hydroxyindoleacetic acid in domestic dogs [PDF]
Frontiers in Veterinary ScienceChronic enteropathies, commonly referred to as inflammatory bowel disease, are multi-factorial disorders that affect a substantial proportion of both the human population and companion animals.
Chloe Cheung +3 more
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