Results 31 to 40 of about 13,827,580 (161)

Vagus Nerve Stimulation in Refractory Epilepsy: Effects on Pro- and Anti-Inflammatory Cytokines in Peripheral Blood [PDF]

, 2010
Objective: The vagus nerve has important immunological functions that may be relevant for its anticonvulsive action. We postulate that this anticonvulsive action is activated by a shift in the immune system resulting in a reduction of neurotoxic and an ...
J.S.H. Vles, Schwarz, J.M., Berfelo, M. W., M. Schwarz, Vles, J. S. H., Schwarz, M., Hulsman, J. A. R. J., A. Myint, Majoie, H. J. M., M.W. Berfelo, Hulsman, J.A.R.J., K. Rijkers, Myint, A., J.A.R.J. Hulsman, Rijkers, K., H.J.M. Majoie   +15 more
core   +1 more source

Kynurenine pathway in post-mortem prefrontal cortex and cerebellum in schizophrenia: relationship with monoamines and symptomatology

Journal of Neuroinflammation, 2021
Background The cortico-cerebellar-thalamic-cortical circuit has been implicated in the emergence of psychotic symptoms in schizophrenia (SZ). The kynurenine pathway (KP) has been linked to alterations in glutamatergic and monoaminergic neurotransmission ...
Amira Ben Afia, Èlia Vila, Karina S. MacDowell, Aida Ormazabal, Juan C. Leza, Josep M. Haro, Rafael Artuch, Belén Ramos, Borja Garcia-Bueno   +8 more
doaj   +1 more source

Depressive disorder and gastrointestinal dysfunction after myocardial infarct are associated with abnormal tryptophan-5-hydroxytryptamine metabolism in rats. [PDF]

PLoS ONE, 2017
In this study, we investigated the relationship between tryptophan-5-hydroxytryptamine metabolism, depressive disorder, and gastrointestinal dysfunction in rats after myocardial infarction.
Xiaofang Lu, Yuefen Wang, Chunyan Liu, Yangang Wang   +3 more
doaj   +1 more source

Tryptophan in banana peel (Musa paradisiaca) as an anti-dementia alternative treatment: A narrative review

JKKI (Jurnal Kedokteran dan Kesehatan Indonesia), 2021
As the prevalence of dementia increases from year to year, the discovery and invention of preventive measures are growing increasingly urgent. Banana peels contain tryptophan, an amino acid that plays a substantial role in the mechanism of dementia ...
Daffara Kinanthi Lustikaiswi, Sapto Yuliani, Rahmah Annura, Elmi Rahmadani   +3 more
doaj   +1 more source

Effect of Disulfiram on the Urinary Excretion of 5-Hydroxytryptophol and 5-Hydroxyindoleacetic Acid in Subjects Consuming Serotonin Rich Foods [PDF]

, 1989
The effect of disulfiram and/or serotonin rich foods (SRF) on the urinary excretion of 5-hydroxytryptophol (5-HTOL) and 5-hydroxyindoleacetic acid (5-HIAA) in normal male subjects was investigated.
Tordecilla, Amy G.
core   +1 more source

Macrogenomic and Metabolomic Analyses Reveal Mechanisms of Gut Microbiota and Microbial Metabolites in Diarrhea of Weaned Piglets

Animals
Recent studies have shown a correlation between piglet diarrhea and the gut microbiota. However, the precise mechanism by which intestinal microorganisms and their metabolites influence diarrhea in weaned piglets remains unclear.
Fei Xie, Mei Zhou, Xiaojin Li, Shenghe Li, Man Ren, Chonglong Wang   +5 more
doaj   +1 more source

Metabolites of Tryptophane and Phenylalanine as Markers of Small Bowel Ischemia-Reperfusion Injury

Open Chemistry, 2018
Ischemic-reperfusion injury of the small intestine is an acute clinical condition with high mortality rate. This study describes the changes in levels of phenylalanine and tryptophan metabolites in intestinal homogenates and urine samples of Wistar male ...
Mašlanková Jana, Tóth Štefan, Tomečková Vladimíra, Tóth Tímea, Katz Matan, Veselá Jarmila, Hertelyová Zdenka, Schnitzer Marek, Živčák Jozef, Mareková Mária   +9 more
doaj   +1 more source

Progression of Carcinoid Heart Disease in the Modern Management Era

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background The development of carcinoid heart disease (CaHD) is still relatively unclear. It is difficult to define an optimal follow‐up for patients without any cardiac involvement at baseline.
Emilie Baron, Catherine Szymanski, Hélène Hergault, Céline Lepère, Olivier Dubourg, Marie Hauguel‐Moreau, Nicolas Mansencal   +6 more
doaj   +1 more source

Serum 5-Hydroxyindoleacetic Acid Measurements for the Diagnosis and Follow-up of Carcinoid Syndrome.

J Clin Endocrinol Metab
Context:The biochemical diagnosis of carcinoid syndrome (CS) is established through the measurement of 24-hour urine 5-hydroxyindoleacetic acid (5-HIAA), but these measurements are prone to sampling error and may be troublesome for patients. Serum 5-HIAA
Kerolles M, Mulders MCF, Mirzaian M, van den Berg SAA, Feelders RA, de Herder WW, Hofland J.   +6 more
europepmc   +2 more sources

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source