Results 51 to 60 of about 13,827,580 (161)

Influence of 2,5-Hexanedione, Acrylamide, Tri-O-Tolyl Phosphate, Leptophos and Methylmercury on Endogenous Levels of Tryptophan, Serotonin and 5-Hydroxyindoleacetic Acid and Serotonin Turnover Rates in Rat Brain [PDF]

, 1992
Several industrial and environmental chemicals cause distal and/or central neuropathy among other diverse toxic effects. Spague-Dawley derived rats were fed doses of 2,5-hexanedione, acrylamide, tri-o-tolyl phosphate, Leptophos and methylmercury via ...
Farr, Craig H.
core   +1 more source

Urinary 5-HIAA as a Potential Diagnostic Marker in Acute Appendicitis: A Preliminary Report of Its Promising Role in Early Detection

Medicina
Background: Acute appendicitis (AA) is a common surgical emergency worldwide. Over the past few decades, diagnostic imaging has become a cornerstone in the identification of acute appendicitis, significantly contributing to the reduction in unnecessary ...
Murat Demir, Alper Gumus, Huseyin Kilavuz, Feyyaz Gungor, Sibel Yaman, Baki Ekci, Idris Kurtulus   +6 more
doaj   +1 more source

Predator stress-induced depression is associated with inhibition of hippocampal neurogenesis in adult male mice

Neural Regeneration Research, 2019
Stress has been suggested to disturb the 5-hydroxytryptamine system and decrease neurogenesis, which contribute to the development of depression. Few studies have investigated the effect of predator stress, a type of psychological stress, on depression ...
Yan-Ping Wu, Hua-Ying Gao, Shu-Hua Ouyang, Hiroshi Kurihara, Rong-Rong He, Yi-Fang Li   +5 more
doaj   +1 more source

Gut microbiota dysbiosis and Long COVID susceptibility in chronic kidney disease

VIEW, EarlyView.
This study investigated gut microbiota dysbiosis and its association with Long COVID susceptibility in 224 hemodialysis patients. We found that 35.3% of patients developed Long COVID, characterized by neurological symptoms and elevated inflammatory markers, accompanied by significant gut microbiota alterations including enriched proinflammatory taxa ...
Meiling Jin, Lijie Ma, Yuqing Yuan, Kaiyi Zhu, Zhaohui Tong, Qianmei Sun   +5 more
wiley   +1 more source

Characterization of a human placental clearance system to regulate serotonin levels in the fetoplacental unit

Reproductive Biology and Endocrinology, 2023
Background Serotonin (5-HT) is a biogenic monoamine with diverse functions in multiple human organs and tissues. During pregnancy, tightly regulated levels of 5-HT in the fetoplacental unit are critical for proper placental functions, fetal development ...
Frantisek Staud, Xin Pan, Rona Karahoda, Xiaojing Dong, Petr Kastner, Hana Horackova, Veronika Vachalova, Udo R. Markert, Cilia Abad   +8 more
doaj   +1 more source

Effect of Social Rank on Gut Microbes and Their Metabolites of Greater Long‐Tailed Hamsters (Tscherskia triton)

Integrative Zoology, EarlyView.
Social rank in greater long‐tailed hamsters (Tscherskia triton) shapes gut microbiota composition and metabolite profiles. Dominant males exhibit a “high‐vigilance, metabolically activated” phenotype, with elevated aggression and specific gut microbiota enriched in energy‐harvesting taxa and fecal queuine.
Da Zhang, Xiaoming Xu, Zhibin Zhang
wiley   +1 more source

Positive association between the plasma levels of 5-hydroxyindoleacetic acid and the severity of depression in patients with chronic obstructive pulmonary disease [PDF]

, 2013
Background: The role of plasma monoamines in patients with chronic obstructive pulmonary disease (COPD) with depression is unclear. To investigate monoamines in 20 depressed patients with COPD, the plasma concentrations of serotonin, 5 ...
Haruki Imaoka, Kosuke Ito, Tomotaka Kawayama, Kazuko Matsunaga, Masaki Okamoto, Nobutaka Edakuni, Yoshihisa Shoji, Tomoaki Hoshino, Tomomi Sekiduka-Kumano, Naohisa Uchimura   +9 more
core   +2 more sources

Acute Inflammatory Bowel Disease Complicating Chronic Alcoholism and Mimicking Carcinoid Syndrome

Case Reports in Gastroenterology, 2012
We report the case of a woman with a history of chronic alcohol abuse who was hospitalized with diarrhea, severe hypokalemia refractory to potassium infusion, nausea, vomiting, abdominal pain, alternations of high blood pressure with phases of ...
Piercarlo Ballo, Pietro Dattolo, Giuseppe Mangialavori, Giuseppe Ferro, Francesca Fusco, Matteo Consalvo, Leandro Chiodi, Francesco Pizzarelli, Alfredo Zuppiroli   +8 more
doaj   +1 more source

Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions

Allergy, EarlyView.
Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira, Lisa Holla, Sophia Björkander, Marie Kaarup Bek, Lorenz Wirth, Patrick A. Shearer, Jesper Säfholm, Erik Sachs, Mamdoh Al‐Ameri, Kasra Vali, Sandra Ekström, Erik Melén, Jenny Mjösberg, Christopher Andrew Tibbitt   +13 more
wiley   +1 more source

Indole-pyruvic acid increases 5-hydroxyindoleacetic acid levels in the cerebrospinal fluid and frontoparietal cortex of the rat: A microdialysis study

, 1990
Indole-pyruvic acid has been found to increase 5-hydroxyindoleacetic acid levels in the cerebro-spinal fluid and fronto-parietal cortex of the rat. This study enlights the potentiality of microdialysis studies in the understanding of more finely tuned ...
Ruggeri M., Fuxe K., Agnati L. F., Zini I., Ungerstedt U., Merlo Pich E.   +5 more
core   +1 more source