Results 71 to 80 of about 13,827,580 (161)

Drugs Affecting 5-HT Systems [PDF]

, 2013
Seminar transcriptIt was in the very early hours of a February morning in 1977 that I first looked down the microscope and saw yellow fluorescence, characteristic of 5-hydroxytryptamine (5-HT) in frozen sections of Octopus brain. After struggling for two
Overy, C, Tansey, EM
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Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, Volume 13, Issue 52, 18 September 2026.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

Comorbidity Mechanism and Management of Chronic Low Back Pain and Major Depressive Disorder: From Neural Circuit Remodeling to Precision Medicine

Brain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Objective This review systematically elaborates multi‐system interactive mechanisms underlying comorbid chronic low back pain (CLBP) and major depressive disorder (MDD), synthesizes recent advances in diagnosis, treatment, and management, and proposes precision medicine directions to address clinical challenges, including missed diagnosis ...
Lin Faqu, Lin Chenjuan, Xiang Xiangyin, Li Xin   +3 more
wiley   +1 more source

Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy [PDF]

, 1999
Purpose: We determined whether neoplastic disease, which was missed under white light can be found during transurethral resection of bladder cancer by 5-aminolevulinic acid-induced porphyrin fluorescence.
Kriegmair, Martin, Knüchel, Ruth, Stepp, Helmut, Zaak, Dirk, Stepp, Herbert, Hofstetter, Alfons, Baumgartner, Reinhold, Dirk Zaak, Helmut Stepp, Reinhold Baumgartner, Martin Kriegmair, Alfons Hofstetter, Herbert Stepp, Ruth Knuechel   +13 more
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Developmental exposure to fluoxetine modulates the serotonin system in hypothalamus.

PLoS ONE, 2013
The selective serotonin reuptake inhibitor (SSRI) fluoxetine (FLU, Prozac®) is commonly prescribed for depression in pregnant women. This results in SSRI exposure of the developing fetus.
Cecilia Berg, Tobias Backström, Svante Winberg, Richard Lindberg, Ingvar Brandt   +4 more
doaj   +1 more source

Serotonin neuromicrobiology: Psychobiotic modulation of the gut–brain axis for mental health

Ibrain, Volume 12, Issue 3, Page 312-329, Fall 2026.
An overview of Psychobiotics and Tryptophan metabolism: A serotonin‐kynurenine crosstalk shaping the Gut‐Brain axis. IDO1, Indoleamine 2,3‐dioxygenase 1; 5‐HT3, 5‐hydroxytryptamine type 3; IFN‐γ, Interferon‐gamma; TNF‐α, Tumor necrosis factor‐alpha; IL‐1β, Interleukin‐1 beta; IL‐6, Interleukin 6; Trp, Tryptophan; 5‐HT, 5‐hydroxy‐tryptamine; 5‐HTP, 5 ...
Nidhi Mandloi, Aarzoo, Chakkaravarthi Saravanan, Heera Ram, Bhim Pratap Singh   +4 more
wiley   +1 more source

From Salt‐Affected Marginal Land Resource to Remediation Agent: Halophyte‐Derived Biochar for Ameliorating Cd‐Contaminated Acidic Soil

Land Degradation &Development, Volume 37, Issue 15, Page 10824-10834, September 2026.
ABSTRACT Cadmium (Cd) contamination of acidic soils poses a significant threat to ecosystem stability and crop health. This study evaluated the potential of biochar derived from the halophyte Salicornia europaea (SBC), a salt‐tolerant plant that grows on saline‐alkali marginal land, to remediate Cd‐contaminated acidic soil.
Shaoqing Ge, Zhenyong Zhao, Ke Zhang, Changyan Tian   +3 more
wiley   +1 more source

Boosting Serotonin Synthesis Is Not Sufficient to Improve Motor Coordination of Mecp2 Heterozygous Mouse Model of Rett Syndrome

Biomolecules
Motor deficit is a core symptom of Rett syndrome, a rare neurological disease caused in most cases by mutations of the methyl-CpG-binding protein2 (MECP2) gene. Serotonin reuptake inhibitors improve motor coordination in Mecp2 heterozygous (Het) mice and
Claudia Villani, Giuseppina Sacchetti, Roberto W. Invernizzi   +2 more
doaj   +1 more source

Amino Acid Metabolism in Health and Disease

MedComm, Volume 7, Issue 9, September 2026.
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su, Jinyu Liu, Xiaoliang Deng, Yanqun Luo, Haiping Xue, Lei Wang, Lianjun Xing, Tao Wu   +7 more
wiley   +1 more source

Determination of 5-hydroxyindoleacetic acid using HPLC with electrochemical detection [PDF]

, 2017
The diploma thesis focuses on a determination of 5-hydroxyindoleacetic acid (5-HIAA) in human urine using a boron-doped diamond film electrode (BDDFE). 5-HIAA is the main final metabolite in the serotonin metabolic pathway and it is used as a biomarker ...
Harvila, Marek
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