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Behavioral effects of α,α,β,β-tetradeutero-5-MeO-DMT in rats: comparison with 5-MeO-DMT administered in combination with a monoamine oxidase inhibitor [PDF]
Ayahuasca is a psychoactive tea prepared from a combination of plants that contain a hallucinogenic tryptamine and monoamine oxidase inhibitors (MAOIs). Behavioral pattern monitor (BPM) experiments demonstrated that the combination of 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) and a behaviorally inactive dose of an MAO(A) inhibitor such as harmaline ...
Adam L Halberstadt +2 more
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Defining 5-MeO-DMT in Historical and Cultural Contexts
World FuturesAzul DelGrasso
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Abstract 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a psychoactive compound found in the parotid gland venom of the Sonoran Desert toad, Incilius alvarius, and certain seeds, leaves, and barks within the Amazonian rainforest. Similar to DMT containing ayahuasca, 5-MeO-DMT has become newly integrated as a spiritual sacrament in ...
Angelica Ukaigwe +2 more
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Angelica Ukaigwe +2 more
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Incilius alvarius cell-based synthesis of 5-MeO-DMT
2022Abstract There is growing interest in the therapeutic potential of 5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine) for psychiatric disorders. While 5-MeO-DMT can be chemically synthesized, the parotoid gland secretions of Incilius alvarius (also known as the Colorado River or Sonoran ...
Leonard Lerer +4 more
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The serotonergic hallucinogen 5-MeO-DMT disrupts cortical activity in rodents
European Neuropsychopharmacology, 2016Trabajo presentado en el 29th ECNP Congress, celebrado en Viena, Austria, del 17 al 20 de septiembre de ...
Artigas, F.; Riga, M.; Celada, P.
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Human Psychopharmacology: Clinical and Experimental, 2022
Edward James +3 more
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Edward James +3 more
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Examining the potential of psilocybin and 5-MeO-DMT as therapeutics for traumatic brain injury
Progress in Neuro-Psychopharmacology and Biological PsychiatryTraumatic brain injury (TBI) is a significant global health challenge, with limited effective treatments for its acute and chronic consequences. TBI is characterized by neuroinflammation, oxidative stress, impaired neuroplasticity, imbalances in neurotransmission, and cell death - factors that contribute to the development of neurological and ...
Zoe, Plummer +5 more
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Fenomenologie 5-MeO-DMT a souvislost s aspekty duševního zdraví
2023Given the increasing knowledge of psychedelic compounds in the field of mental health care provided by scientific research in recent decades, the aftereffects of 5-MeO-DMT on aspects of mental health are relatively unexplored. Its unique acute subjective effects can be observed within phenomenology.
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