Relaxed Beliefs After Psychedelics: From Sensory Processing to Mystical States [PDF]
This dissertation explores the lasting impact of psychedelic use on brain networks, ranging from basic sensory processing to abstract mystical experiences.
Jacobs, Chloe Lily West
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Orally Active Forms of DMT, 5-MeO-DMT, and Long-Acting MDMA for the Treatment of Neuropsychiatric Disorders. [PDF]
Kargbo RB.
europepmc +1 more source
Complex slow waves radically reorganise human brain dynamics under 5-MeO-DMT
Abstract5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a psychedelic drug known for its uniquely profound effects on subjective experience, reliably eradicating the perception of time, space, and the self. However, little is known about how this drug alters large-scale brain activity.
George Blackburne +6 more
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Prospective Associations of Psychedelic Treatment for Co-Occurring Alcohol Misuse and Posttraumatic Stress Symptoms Among United States Special Operations Forces Veterans [PDF]
This study evaluated prospective associations of ibogaine and 5-MeO-DMT treatment for risky alcohol use and post-traumatic stress disorder (PTSD) symptoms among United States (US) Special Operations Forces Veterans (SOFV).
Armstrong, Stacey B +5 more
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Psychedelic trip sitting, dosages and intensities: Supplementing clinical studies with anecdotal reports [PDF]
Background and aims: Online communities provide insights into psychedelic consumption, assisting in identification of trends, informing both harm reduction provisions and clinical research.
Bright, Stephen J. +3 more
core +2 more sources
Smart shops: a survey of products, claimed effects and medical-toxicological relevance [PDF]
During the last few years the use of herbal drugs of abuse, so-called 'smart products' and eco-drugs has increased. Many of these products have psychoactive effects.
Beltman W +6 more
core
Intranasal 5-MeO-DMT Concomitant with SSRI for Treatment-Resistant Depression: A Proof-of-Concept Trial. [PDF]
Seynaeve M +6 more
europepmc +1 more source
Background: 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT), also officially known as Mebufotenin, is a naturally occurring serotonergic psychedelic alkaloid found in the venom of the Sonoran Desert toad (Incilius alvarius) and various plant species.
Burton J. Tabaac +5 more
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The acute effects of 5-MeO-DMT on behaviour, brain activity and arousal in mice
The serotonergic system plays an important role in the subcortical control of global sleep-wake states, as supported by observations that the administration of serotonergic psychedelics suppresses paradoxical sleep and results in increased sleep fragmentation.
openaire +2 more sources
Since depression is a common mental illness affecting an estimated 5% of people worldwide, investigators are encouraged to develop effective antidepressants. According to the monoamine-deficiency hypothesis, the underlying pathophysiology of depression is a deficiency of some neurotransmitters (serotonin, norepinephrine, or dopamine) in the central ...
Rajagopal, Kalirajan +5 more
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