Results 91 to 100 of about 11,769,643 (158)

Neural effects and phenomenology of nondual meditation and 5-MeO-DMT in an expert meditation practitioner

Meditation and psychedelics have separately been studied as powerful tools for probing consciousness through their capacity to deconstruct the sense of self. Yet, direct empirical comparisons remain scarce, particularly in expert meditators.
Stéphane Offort, John Dunne, James Sanders, David Erritzoe, Christopher Timmermann, Tommaso Barba, Antoine Lutz   +6 more
core  

The natural hallucinogen 5-MeO-DMT, component of Ayahuasca, disrupts cortical function in rats: reversal by antipsychotic drugs

5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a natural hallucinogen component of Ayahuasca, an Amazonian beverage traditionally used for ritual, religious and healing purposes that is being increasingly used for recreational purposes in US and Europe.
Riga, Maurizio S., Artigas Pérez, Francesc, Soria, Guadalupe, Tudela Fernández, Raúl, Celada Pedrosa, Paz   +4 more
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Influence du contexte d'administration sur les effets pharmacologiques des psychédéliques diméthyltryptamine (DMT) et 5-méthoxy-diméthyltryptamine (5-MeO-DMT)

The concept of set and setting refers to the extrapharmacological variables influencing the psychedelic experience. The primary objective of this study was to evaluate, using a translational approach, whether the administration context (setting) could ...
Hacquet, Romain
core   +1 more source

In vitro and in silico evaluation of 5-MeO-DMT, LSD, and mescaline’s interaction with CYP450 enzymes

5-Methoxy-N,N-dimethyltryptamine(5-MeO-DMT), lysergic acid diethylamide (LSD), and mescaline are classic hallucinogens known for their recreational use, which increased in the last dec-ades. Despite some available data on the metabolism of these drugs [1-
Madureira-Carvalho, Áurea, Dinis-Oliveira, Ricardo Jorge, Sousa, Sérgio F., Brito-da-Costa, Andreia Machado, Carvalho, Mariana, Silva, Diana Dias da, Dias da Silva, Diana Cristina   +6 more
core   +1 more source

5-MeO-DMT Use in Humans: A Scoping Review of Peer-Reviewed Research

Clinical trials using 5-MeO-DMT to treat various mental health conditions are currently underway, however research on 5-MeO-DMT use in humans is limited. To date, no scoping review of the published, peer-reviewed literature exists. The purpose of the present analysis is to examine the extent, range, and nature of peer-reviewed research on the use of 5 ...
Michael Esposito, Ana M Ortiz Bernal, Alan K. Davis, Rafaelle Lanza Lancelotta   +3 more
openaire   +1 more source

Inhalable Psychedelic 5-MeO-DMT Shows Promise in Treatment-Resistant Depression. [PDF]

J Med Chem
Ali S, Tian X, Anastasio NC, Cunningham KA, Zhou J.   +4 more
europepmc   +1 more source

Antipsychotic drugs reverse the disruption in prefrontal cortex function produced by the serotonergic hallucinogen 5-Methoxy-N,N-Dimethyltriptamine (5-MeO-DMT)

, 2014
Trabajo presentado al 8th Forum of Neuroscience (FENS) celebrado en Barcelona del 14 al 18 de julio de 2012.5-MeO-DMT is a natural hallucinogen, component of Ayahuasca (Amazonian beverage), that acts as a non-selective serotonin 5-HT1A/5-HT2A receptor ...
Riga, Maurizio, Artigas, Francesc, Celada, Pau   +2 more
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El alucinógeno 5-MeO-DMT reduce las oscilaciones lentas (<4Hz) en corteza prefrontal. Reversión por fármacos antipsicóticos

, 2014
Trabajo presentado al XIV Congreso Nacional de la Sociedad Española de Neurociencia celebrado del 28 al 30 de septiembre de 2011.[Objetivos]: Estudiar la base neurobiológica de las alucinaciones usando el alucinógeno natural 5-MeO-DMT (componente de ...
Riga, Maurizio, Artigas, Francesc, Celada, Pau   +2 more
core  

The acute effects of 5-MeO-DMT on behaviour, brain activity and arousal in mice

The serotonergic system plays an important role in the subcortical control of global sleep-wake states, as supported by observations that the administration of serotonergic psychedelics suppresses paradoxical sleep and results in increased sleep fragmentation.
openaire   +2 more sources

Intranasal 5-MeO-DMT Concomitant with SSRI for Treatment-Resistant Depression: A Proof-of-Concept Trial. [PDF]

CNS Drugs
Seynaeve M, Dunbar F, Hindocha C, Ermakova AO, Pierce M, Conley RR, Roberts C.   +6 more
europepmc   +1 more source