Results 81 to 90 of about 11,769,643 (158)

A Fully Validated LC-MS Quantitation Method for Psychoactive Compounds Found in Native South American Plant Species

open access: yesPsychoactives
Psychoactive drugs are compounds that alter the function of the central nervous system, resulting in changes in perception, mood, cognition, and behavior.
Jonathan Tran   +4 more
doaj   +1 more source

The effect of single administration of 5-MeO-DMT on selected personality characteristics

open access: yes, 2018
The inhalation of vaporized 5-MeO-DMT, the psychoactive constituent of the venom of the Colorado River toad (Incilius alvarius), is used for spiritual and recreational reasons.
Jan Benda, Lucie Havlínová
core   +1 more source

Criticality supports cross-frequency cortical-thalamic information transfer during conscious states

open access: yeseLife
Consciousness is thought to be regulated by bidirectional information transfer between the cortex and thalamus, but the nature of this bidirectional communication - and its possible disruption in unconsciousness - remains poorly understood.
Daniel Toker   +10 more
doaj   +1 more source

5-MeO-DMT induces NEIL3-independent acute cell proliferation in the adult dentate gyrus

open access: yes
Adult dentate gyrus neurogenesis and cell proliferation are regulated by multiple physiological inputs, including experience-dependent signals that have been linked to the DNA glycosylase NEIL3.
Rafael V. Lima da Cruz   +2 more
core   +1 more source

Best practices for first psychedelic experiences: harm reduction advice from the psychedelic community

open access: yesHarm Reduction Journal
Background The use of psychedelics is currently increasing in the United States. Awareness of clinical trials investigating the therapeutic applications of psychedelics may result in a record number of people who use psychedelics for the first-time. This
Daniel J. Kruger   +7 more
doaj   +1 more source

Preclinical Comparison of DMT and 5-MeO-DMT Reveals Behavioral Dissociation, Distinct TrkB Activation and Differential Plasticity Profiles

open access: yes
N, N-dimethyltryptamine (DMT) and 5-methoxy-N, N-dimethyltryptamine (5-MeO-DMT) are structurally related tryptamine psychedelics with emerging therapeutic potential, yet their comparative acute pharmacology and longer-term neuroplastic effects remain ...
Orr Shahar   +9 more
core   +1 more source

The light at the end of the tunnel:Safety and efficacy of 5-MEO-DMT in treatment-resistant depression [PDF]

open access: yes
The research described in this thesis focused on the psychedelic and psychoactive effects of the psychedelic drug Mebufotenin (5-MeO-DMT), as well as its safety and therapeutic efficacy.
Reckweg, Johannes Tobias
core   +1 more source

Adverse events of DMT, 5-MeO-DMT, and ayahuasca according to the setting of administration: A systematic review

open access: yes
International audienceIntroduction: The set (individual dispositions) and setting (environment) during psychedelics administration influence their psychotropic effects and could modulate adverse psychiatric reactions.
P. Guiard, B.   +4 more
core   +3 more sources

Psychedelic Therapy: A Primer for Primary Care Clinicians—5-Methoxy-N,N-Dimethyltryptamine (5-MeO-DMT)

open access: yes
Background: 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT), also officially known as Mebufotenin, is a naturally occurring serotonergic psychedelic alkaloid found in the venom of the Sonoran Desert toad (Incilius alvarius) and various plant species ...
Owen S. Muir   +5 more
core  

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