Results 71 to 80 of about 11,769,643 (158)

Dos efeitos ansiolíticos da 5-MeO-DMT no cérebro e comportamento do camundongo [PDF]

, 2022
Anxiety is a worldwide prevalent circuitopathy, in other words, a circuit disorder that substantially affects people's quality of life. To treat it properly, it is necessary to reverse the processes that lead to the malfunctioning of neuronal circuits ...
Lima, Margareth de Brito Nogueira
core  

Bridging Scales in Flexible Perovskite Solar Cells: Mechanisms, Interfaces, and Applications

Advanced Science, Volume 13, Issue 12, 27 February 2026.
This perspective focuses on the advancement of flexible perovskite solar cells (f‐PSCs) from the energetic point of view, and summarizes the mechanisms, material characteristics, device performance, and failure mechanisms across the microscopic, mesoscopic, and macroscopic scales through mechanical energy dissipation theory.
Yan Wang, Zexin Yu, Chunlei Zhang, Ning Wang, Francesco Vanin, Bo Li, Nan Li, Meng Liao, Zonglong Zhu   +8 more
wiley   +1 more source

Hemp Proteins Conjugated with Green Tea Polyphenol Extract Form De Novo Plant‐Sourced Emulsifiers Suitable for Nanodelivery Systems Bearing Lipophilic Psychopharmaceuticals

Advanced Therapeutics, Volume 8, Issue 11, November 2025.
Green tea polyphenols, conjugated either covalently or non‐covalently to hemp protein, comprise an excellent stabilizing matrix for oxidatively‐sensitive small molecules. These nanoemulsions are highly stable to a variety of chemical and physical stressors, protecting the small molecule while allowing for easy uptake across cell membranes and rapid ...
William Charles Hosie, Abhinandan Banerjee, Mary Augustina Egbuta, Kasra Razmkhah, Behzad Bolandi, Khalilalrahman Dehvari, Anton Homon, Aleena Kappadakunnel, Jonathan J. Simone, John F. Trant   +9 more
wiley   +1 more source

Neurotoxic and Neuroprotective Effects of Psychedelics in a Human Neuroblastoma Cell Model

RevSALUS
Psychedelic compounds, including psilocybin, psilocin, lysergic acid diethylamide (LSD), 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), and mescaline, have long been recognized for their recreational effects and involvement in forensic cases.
Andreia Machado Brito da Costa, Ricardo Jorge Dinis-Oliveira, Áurea Madureira-Carvalho, Diana Dias-da-Silva   +3 more
doaj   +1 more source

Classification of psychedelics and psychoactive drugs based on brain-wide imaging of cellular c-Fos expression

Nature Communications
Psilocybin, ketamine, and MDMA are psychoactive compounds that exert behavioral effects with distinguishable but also overlapping features. The growing interest in using these compounds as therapeutics necessitates preclinical assays that can accurately ...
Farid Aboharb, Pasha A. Davoudian, Ling-Xiao Shao, Clara Liao, Gillian N. Rzepka, Cassandra Wojtasiewicz, Jonathan Indajang, Mark Dibbs, Jocelyne Rondeau, Alexander M. Sherwood, Alfred P. Kaye, Alex C. Kwan   +11 more
doaj   +1 more source

Open-label study of consecutive ibogaine and 5-MeO-DMT assisted-therapy for trauma-exposed male Special Operations Forces Veterans: prospective data from a clinical program in Mexico

, 2023
Background: Research in psychedelic medicine has focused primarily on civilian populations. Further study is needed to understand whether these treatments are effective for Veteran populations.
Alan Kooi Davis (17463841), Lynnette A. Averill (5923283), Yitong Xin (17390520), Nathan Sepeda (17463844)   +3 more
core   +1 more source

Effects of NN-DMT and 5-MeO-DMT treatment on the gene expression and secretion of cytokines and chemokines in LPS-stimulated moDCs.

, 2014
A: MoDCs were incubated with 100 µM NN-DMT (NN-DMT) or 5-MeO-DMT (5-MeO-DMT) for 8 h or left untreated (ctrl) were used as controls. Additionally, cells were either activated with 500 ng/ml LPS alone for 8 h, or pre-treated with tryptamines for 1 hour ...
Attila Szabo (279820), Attila Kovacs (337522), Ede Frecska (623501), Eva Rajnavolgyi (114375)   +3 more
core   +1 more source

The serotonin hallucinogen 5-MeO-DMT alters cortico-thalamic activity in freely moving mice: Regionally-selective involvement of 5-HT1A and 5-HT2A receptors

, 2020
5-MeO-DMT is a natural hallucinogen acting as serotonin 5-HT/5-HT receptor agonist. Its ability to evoke hallucinations could be used to study the neurobiology of psychotic symptoms and to identify new treatment targets. Moreover, recent studies revealed
Riga, Maurizio, Lladó-Pelfort, Laia, Artigas, Francesc, Celada, Pau   +3 more
core   +1 more source

With great power comes great responsibility: Promise and caution in the new psychedelic renaissance

Brain Disorders
Clinicians and researchers are showing increased interest in psychedelic-assisted therapy for patients who don't show improvement from using conventional antidepressants.
Matthew Halma, Rakeem Levy, Joseph Varon
doaj   +1 more source

The hallucinogen 5-MeO-DMT simultaneously alters oscillatory activity in prefrontal and visual cortex: regionally-selective reversal by risperidone and 5-HT1A-R receptor blockade

, 2017
Trabajo presentado en el 10th FENS Forum of Neuroscience (FENS 2016), celebrado en Copenhague, Dinamarca, del 2 al 6 de julio de 2016[Background] 5-MeO-DMT is a natural hallucinogen acting as non-selective 5-HT1A/5-HT2A receptor agonist.
Riga, Maurizio, Lladó-Pelfort, Laia, Artigas, Francesc, Celada, Pau   +3 more
core