Results 31 to 40 of about 457,835 (262)

Editorial 57-1

Revista Brasileira de Cancerologia, 2011
Nesse primeiro número de 2011, a RBC traz seis artigos originais, dois relatos de caso, duas revisões de literatura e uma resenha. Além disso, publica os resumos de trabalhos selecionados para apresentação no XII Congresso da Sociedade Brasileira de ...
Teresa Caldas Camargo
doaj  

A dominant RAD51C pathogenic splicing variant predisposes to breast and ovarian cancer in the Newfoundland population due to founder effect

Molecular Genetics & Genomic Medicine, 2020
Background RAD51C is important in DNA repair and individuals with pathogenic RAD51C variants have increased risk of hereditary breast and ovarian cancer syndrome (HBOC), an autosomal dominant genetic predisposition to early onset breast and/or ovarian ...
Lesa M. Dawson, Kerri N. Smith, Salem Werdyani, Robyn Ndikumana, Cindy Penney, Louisa L. Wiede, Kendra L. Smith, Justin A. Pater, Andrée MacMillan, Jane Green, Sheila Drover, Terry‐Lynn Young, Darren D. O’Rielly   +12 more
doaj   +1 more source

Perfusion Bioreactor Culture Incorporating Mechanical Confinement Enhances Mesenchymal Stem Cell Extracellular Vesicle Production and Wound Healing Potential

Advanced Materials Technologies, EarlyView.
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner, Raith Nowak, Stephanie M. Kronstadt, Nicholas H. Pirolli, Talia J. Solomon, Kristin Nikolov, William Pieper Holeman, Ian M. Smith, Kimberly M. Stroka, John P. Fisher, Steven M. Jay   +10 more
wiley   +1 more source

Effects of the cationic protein poly-L-arginine on airway epithelial cells in vitro

Mediators of Inflammation, 2002
Background: Allergic asthma is associated with an increased number of eosinophils in the airway wall. Eosinophils secrete cationic proteins, particularly major basic protein (MBP).
Shahida Shahana, Caroline Kampf, Godfried M. Roomans   +2 more
doaj   +1 more source

Case Reports and Experts Opinions about Current Use of Leech Therapy in Dermatology and Cosmetology

Cosmetics, 2022
This article aimed to determine the experts’ opinion on the use of hirudotherapy in cosmetology, to supplement knowledge, and to identify factors that, in the opinion of experts, affect the effectiveness and frequency of use of this method in eliminating
Ewelina Ząbkowska, Olga Czerwińska-Ledwig, Magdalena Bartnicka, Anna Piotrowska   +3 more
doaj   +1 more source

From Strain to Pressure: Atomically Resolved Mechanisms of Stress Dissipation in Emissive, Elastically Deformable Molecular Crystals Under Ambient and High Pressure

Advanced Optical Materials, EarlyView.
Molecular crystals must withstand both isotropic and anisotropic stress to function in flexible optoelectronics and high‐pressure devices. In situ high‐pressure single‐crystal X‐ray diffraction coupled with DFT‐D computations reveal how an emissive molecular crystal with interdigitated packing bends elastically at ambient‐pressure and remains ...
Arif H. Dar, Vikram C. Joshi, Alexandra Longcake, Tamador Alkhidir, Ayat Al Nimer, Praveen B. Managutti, Shamraiz H. Talib, Jaime Viegas, Michael R. Probert, Changquan C. Sun, Sharmarke Mohamed   +10 more
wiley   +1 more source

The Effects of Intermittent Hypoxic Training on Anaerobic Performance in Young Men

Applied Sciences
This study aimed to comprehensively evaluate the effects of intermittent hypoxic training (IHT) on anaerobic performance in young, untrained men. Young men (n = 48) were randomly divided into two training groups and a control group.
Marcin Maciejczyk, Tomasz Palka, Magdalena Wiecek, Sebastian Masel, Zbigniew Szygula   +4 more
doaj   +1 more source

From Pores to Pavement: Advanced Modeling of Aluminosilicates for Scalable Carbon Capture in Concrete

Advanced Science, EarlyView.
This study presents a transferable modeling framework for carbon capture using aluminosilicates, integrating Universal Isotherm Modeling with experimental data. It reveals how ultramicropores, alumina content, and amine functionalization influence CO2 adsorption energetics.
Pooja Anil Kumar Nair, Jéssica de O. N. Ribeiro, Murilo Daniel de Mello Innocentini, Kevin Paine, Juliana Calabria‐Holley   +4 more
wiley   +1 more source

The Use of Cryotherapy in Cosmetology and the Influence of Cryogenic Temperatures on Selected Skin Parameters—A Review of the Literature

Cosmetics, 2022
Cryotherapy is becoming an increasingly popular method used in medicine, physiotherapy, and cosmetology. It is used in the form of whole-body cryotherapy (WBC) and local cryotherapy.
Adrianna Dzidek, Anna Piotrowska
doaj   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source