Results 1 to 10 of about 1,318,093 (377)

Common miR-590 Variant rs6971711 Present Only in African Americans Reduces miR-590 Biogenesis. [PDF]

PLoS ONE, 2016
MicroRNAs (miRNAs) are recognized as important regulators of cardiac development, hypertrophy and fibrosis. Recent studies have demonstrated that genetic variations which cause alterations in miRNA:target interactions can lead to disease. We hypothesized
Xiaoping Lin, Steven Steinberg, Suresh K Kandasamy, Junaid Afzal, Blaid Mbiyangandu, Susan E Liao, Yufan Guan, Celia P Corona-Villalobos, Scot J Matkovich, Neal Epstein, Dotti Tripodi, Zhaoxia Huo, Garry Cutting, Theodore P Abraham, Ryuya Fukunaga, M Roselle Abraham   +15 more
doaj   +7 more sources

Exosomal miR-590-5p in Serum as a Biomarker for the Diagnosis and Prognosis of Gastric Cancer

Frontiers in Molecular Biosciences, 2021
The purpose of this study is to explore the expression of miRNA-590-5p, an exosome of gastric cancer (GC), and to evaluate the suitability of miR-590-5p, an exosome with its own clinical characteristics. Serum samples from 168 gastric cancer patients and
Guo-Dian Zheng, Zhi-Yuan Xu, Can Hu, Hang Lv, Hua-Xia Xie, Ting Huang, Yan-Qiang Zhang, Gui-Ping Chen, Yu-Fei Fu, Xiang-Dong Cheng   +9 more
doaj   +2 more sources

miR-590-5p Overexpression Alleviates β-Amyloid-Induced Neuron Damage via Targeting Pellino-1

Analytical Cellular Pathology, 2022
Alzheimer’s disease (AD) is one common degenerative disorder. However, the effects of miR-590-5p on AD and the mechanism on modulation of AD development were unclear.
Lin Shang, Tao Peng, Xuemei Chen, Zhiyong Yan, Junmin Wang, Xiaoqun Gao, Cheng Chang   +6 more
doaj   +2 more sources

miR-590-5p mediates mitochondrial respiration, proliferation, and apoptosis in thyroid carcinoma cells via fibroblast growth factor receptor substrate 2 [PDF]

Archives of Endocrinology and Metabolism
Objective: Thyroid carcinoma (TC) is the most common cancer of the endocrine system. Dysregulation of microRNA-590-5p (miR-590-5p) has been associated with various malignancies. Targeting mitochondrial respiration is beneficial in treating TC. This study
Penghui Wang, Xiaoli Hou, Wei Sun, Jiajie Chen, Yasen Cao, Hong Cheng   +5 more
doaj   +2 more sources

Circ_0124644 Serves as a ceRNA for miR-590-3p to Promote Hypoxia-Induced Cardiomyocytes Injury via Regulating SOX4

Frontiers in Genetics, 2021
Circular RNA (circRNA) is an important factor for regulating the progression of many cardiovascular diseases, including acute myocardial infarction (AMI). However, the role of circ_0124644 in AMI progression remains unclear.
Juan Tan, Weinan Pan, Huilin Chen, Yafang Du, Peiyong Jiang, Dianmei Zeng, Jie Wu, Kuang Peng   +7 more
doaj   +2 more sources

Khosrow II (590–628 CE)

Encyclopedia, 2022
Khosrow II (r. 590–628 CE) was the last great Sasanian king who took the throne with the help of the Romans and broke with dynastic religious preferences as he became married to a Christian empress.
Mahdi Motamedmanesh, Samira Royan
doaj   +2 more sources

Exosomal miR-590-3p derived from cancer-associated fibroblasts confers radioresistance in colorectal cancer

Molecular Therapy: Nucleic Acids, 2021
Radiotherapeutic resistance is a major obstacle for the effective treatment of colorectal cancer (CRC). MicroRNAs (miRNAs) play a critical role in chemoresistance and radioresistance.
Xijuan Chen, Yingqiang Liu, Qinglan Zhang, Baoxing Liu, Yan Cheng, Yonglei Zhang, Yanan Sun, Junqi Liu   +7 more
doaj   +2 more sources

The lncRNA PVT1/miR-590-5p/FSTL1 axis modulates the proliferation and migration of airway smooth muscle cells in asthma

Autoimmunity, 2021
Objective Asthma is a prevalent chronic inflammatory airway disease that is characterised by airway remodelling and airway hyperresponsiveness. Abnormal proliferation and migration of airway smooth muscle cells (ASMCs) contribute to airway remodelling in
Wen-Lan Wang, Xiao-Ming Luo, Qin Zhang, Hai-Qiao Zhu, Guo-Qing Chen, Qin Zhou   +5 more
doaj   +2 more sources

Circular RNA circ_0020123 promotes non-small cell lung cancer progression by sponging miR-590-5p to regulate THBS2

Cancer Cell International, 2020
Background The incidence and death rate of non-small cell lung cancer (NSCLC) in China ranks the first among the malignant tumors. Circular RNA (circRNA) was reported to be involved in the progression of NSCLC.
Liang Wang, Lantao Zhao, Yonghong Wang
doaj   +2 more sources

Linc02381 Exacerbates Rheumatoid Arthritis Through Adsorbing miR-590-5p and Activating the Mitogen-Activated Protein Kinase Signaling Pathway in Rheumatoid arthritis-fibroblast-like synoviocytes

Cell Transplantation, 2020
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease. New evidence suggested that linc02381 suppressed colorectal cancer progression by regulating PI3 K signaling pathway, but the role of linc02381 in other diseases, such as RA, remains ...
Jing Wang, Qing Zhao
doaj   +2 more sources