Results 1 to 10 of about 276,243 (334)

Exosomal miR-590-5p in Serum as a Biomarker for the Diagnosis and Prognosis of Gastric Cancer

Frontiers in Molecular Biosciences, 2021
The purpose of this study is to explore the expression of miRNA-590-5p, an exosome of gastric cancer (GC), and to evaluate the suitability of miR-590-5p, an exosome with its own clinical characteristics. Serum samples from 168 gastric cancer patients and
Guo-Dian Zheng, Zhi-Yuan Xu, Can Hu, Hang Lv, Hua-Xia Xie, Ting Huang, Yan-Qiang Zhang, Gui-Ping Chen, Yu-Fei Fu, Xiang-Dong Cheng   +9 more
doaj   +2 more sources

miR-590-5p Overexpression Alleviates β-Amyloid-Induced Neuron Damage via Targeting Pellino-1

Analytical Cellular Pathology, 2022
Alzheimer’s disease (AD) is one common degenerative disorder. However, the effects of miR-590-5p on AD and the mechanism on modulation of AD development were unclear.
Lin Shang, Tao Peng, Xuemei Chen, Zhiyong Yan, Junmin Wang, Xiaoqun Gao, Cheng Chang   +6 more
doaj   +2 more sources

Circ_0124644 Serves as a ceRNA for miR-590-3p to Promote Hypoxia-Induced Cardiomyocytes Injury via Regulating SOX4

Frontiers in Genetics, 2021
Circular RNA (circRNA) is an important factor for regulating the progression of many cardiovascular diseases, including acute myocardial infarction (AMI). However, the role of circ_0124644 in AMI progression remains unclear.
Juan Tan, Weinan Pan, Huilin Chen, Yafang Du, Peiyong Jiang, Dianmei Zeng, Jie Wu, Kuang Peng   +7 more
doaj   +2 more sources

590 nm LED Irradiation Improved Erythema through Inhibiting Angiogenesis of Human Microvascular Endothelial Cells and Ameliorated Pigmentation in Melasma

Cells, 2022
Melasma is a common refractory acquired pigmentary skin disease that mainly affects middle-aged women. The pathogenesis of melasma is still uncertain, while abnormal vascular endothelial cells may play a role.
Xiaoxi Dai, Shanglin Jin, Yijie Xuan, Yiwen Yang, Xiaoli Lu, Chen Wang, Li Chen, Leihong Xiang, Chengfeng Zhang   +8 more
doaj   +2 more sources

The lncRNA PVT1/miR-590-5p/FSTL1 axis modulates the proliferation and migration of airway smooth muscle cells in asthma

Autoimmunity, 2021
Objective Asthma is a prevalent chronic inflammatory airway disease that is characterised by airway remodelling and airway hyperresponsiveness. Abnormal proliferation and migration of airway smooth muscle cells (ASMCs) contribute to airway remodelling in
Wen-Lan Wang, Xiao-Ming Luo, Qin Zhang, Hai-Qiao Zhu, Guo-Qing Chen, Qin Zhou   +5 more
doaj   +2 more sources

Circular RNA circ_0020123 promotes non-small cell lung cancer progression by sponging miR-590-5p to regulate THBS2

Cancer Cell International, 2020
Background The incidence and death rate of non-small cell lung cancer (NSCLC) in China ranks the first among the malignant tumors. Circular RNA (circRNA) was reported to be involved in the progression of NSCLC.
Liang Wang, Lantao Zhao, Yonghong Wang
doaj   +2 more sources

Prognostic value of circ_0000043/miR-590-5p in cervical cancer and regulation of tumor progression [PDF]

Discover Oncology
Objective To investigate the prognostic value of circ_0000043 in cervical cancer (CC) and its involvement in the modulation of patients’ prognostic progression.
Yue Zhu, Xi Shi, Shanshan Zhang, Hongyin Cui, Baohua Wu   +4 more
doaj   +2 more sources

Linc02381 Exacerbates Rheumatoid Arthritis Through Adsorbing miR-590-5p and Activating the Mitogen-Activated Protein Kinase Signaling Pathway in Rheumatoid arthritis-fibroblast-like synoviocytes

Cell Transplantation, 2020
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease. New evidence suggested that linc02381 suppressed colorectal cancer progression by regulating PI3 K signaling pathway, but the role of linc02381 in other diseases, such as RA, remains ...
Jing Wang, Qing Zhao
doaj   +2 more sources

Role of lncRNA TPRG1-AS1 in the development of cervical squamous cell carcinoma and its prognostic value [PDF]

Discover Oncology
Objective Cervical squamous cell carcinoma (CSCC) has a poor prognosis due to persistent HPV infection. LncRNA TPRG1-AS1 is linked to regulating the development of many cancers, so the regulatory mechanism and prognostic value of TPRG1-AS1 in CSCC were ...
Yang Fan, Lan Ye, Shuyu Wang, Junwei Wang, Ke Wang, Ying Li   +5 more
doaj   +2 more sources

First-line pembrolizumab + chemotherapy in Japanese patients with advanced/metastatic esophageal cancer from KEYNOTE-590

Esophagus, 2022
The phase 3 KEYNOTE-590 (NCT03189719) study showed first-line pembrolizumab plus chemotherapy significantly prolonged overall survival and progression-free survival versus placebo plus chemotherapy in patients with advanced unresectable or metastatic ...
T. Kojima, H. Hara, A. Tsuji, H. Yasui, K. Muro, T. Satoh, T. Ogata, R. Ishihara, M. Goto, Hideo Baba, T. Nishina, S. Han, Tomoko Sakata, Naoyoshi Yatsuzuka, T. Doi, Ken Kato   +15 more
semanticscholar   +1 more source