Results 1 to 10 of about 1,270,133 (397)

Exosomal miR-590-5p in Serum as a Biomarker for the Diagnosis and Prognosis of Gastric Cancer

open access: yesFrontiers in Molecular Biosciences, 2021
The purpose of this study is to explore the expression of miRNA-590-5p, an exosome of gastric cancer (GC), and to evaluate the suitability of miR-590-5p, an exosome with its own clinical characteristics. Serum samples from 168 gastric cancer patients and
Guo-Dian Zheng   +9 more
doaj   +2 more sources

miR-590-5p Overexpression Alleviates β-Amyloid-Induced Neuron Damage via Targeting Pellino-1

open access: yesAnalytical Cellular Pathology, 2022
Alzheimer’s disease (AD) is one common degenerative disorder. However, the effects of miR-590-5p on AD and the mechanism on modulation of AD development were unclear.
Lin Shang   +6 more
doaj   +2 more sources

Circ_0124644 Serves as a ceRNA for miR-590-3p to Promote Hypoxia-Induced Cardiomyocytes Injury via Regulating SOX4

open access: yesFrontiers in Genetics, 2021
Circular RNA (circRNA) is an important factor for regulating the progression of many cardiovascular diseases, including acute myocardial infarction (AMI). However, the role of circ_0124644 in AMI progression remains unclear.
Juan Tan   +7 more
doaj   +2 more sources

The Changing-Look Quasar Mrk 590 is Awakening [PDF]

open access: yesThe Astrophysical Journal, 2018
Mrk 590 was originally classified as a Seyfert 1 galaxy, but then it underwent dramatic changes: the nuclear luminosity dropped by over two orders of magnitude and the broad emission lines all but disappeared from the optical spectrum. Here we present followup observations to the original discovery and characterization of this "changing look" active ...
G. De Rosa   +14 more
arxiv   +6 more sources

Khosrow II (590–628 CE)

open access: yesEncyclopedia, 2022
Khosrow II (r. 590–628 CE) was the last great Sasanian king who took the throne with the help of the Romans and broke with dynastic religious preferences as he became married to a Christian empress.
Mahdi Motamedmanesh, Samira Royan
doaj   +2 more sources

590 nm LED Irradiation Improved Erythema through Inhibiting Angiogenesis of Human Microvascular Endothelial Cells and Ameliorated Pigmentation in Melasma

open access: yesCells, 2022
Melasma is a common refractory acquired pigmentary skin disease that mainly affects middle-aged women. The pathogenesis of melasma is still uncertain, while abnormal vascular endothelial cells may play a role.
Xiaoxi Dai   +8 more
doaj   +2 more sources

The lncRNA PVT1/miR-590-5p/FSTL1 axis modulates the proliferation and migration of airway smooth muscle cells in asthma

open access: yesAutoimmunity, 2021
Objective Asthma is a prevalent chronic inflammatory airway disease that is characterised by airway remodelling and airway hyperresponsiveness. Abnormal proliferation and migration of airway smooth muscle cells (ASMCs) contribute to airway remodelling in
Wen-Lan Wang   +5 more
doaj   +2 more sources

Common miR-590 Variant rs6971711 Present Only in African Americans Reduces miR-590 Biogenesis.

open access: yesPLoS ONE, 2016
MicroRNAs (miRNAs) are recognized as important regulators of cardiac development, hypertrophy and fibrosis. Recent studies have demonstrated that genetic variations which cause alterations in miRNA:target interactions can lead to disease. We hypothesized
Xiaoping Lin   +15 more
doaj   +5 more sources

Circular RNA circ_0020123 promotes non-small cell lung cancer progression by sponging miR-590-5p to regulate THBS2

open access: yesCancer Cell International, 2020
Background The incidence and death rate of non-small cell lung cancer (NSCLC) in China ranks the first among the malignant tumors. Circular RNA (circRNA) was reported to be involved in the progression of NSCLC.
Liang Wang, Lantao Zhao, Yonghong Wang
doaj   +2 more sources

Prognostic value of circ_0000043/miR-590-5p in cervical cancer and regulation of tumor progression [PDF]

open access: yesDiscover Oncology
Objective To investigate the prognostic value of circ_0000043 in cervical cancer (CC) and its involvement in the modulation of patients’ prognostic progression.
Yue Zhu   +4 more
doaj   +2 more sources

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