Results 1 to 10 of about 243,130 (240)

MiR‐590 Promotes Transdifferentiation of Porcine and Human Fibroblasts Toward a Cardiomyocyte‐Like Fate by Directly Repressing Specificity Protein 1

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundReprogramming of cardiac fibroblasts into induced cardiomyocyte‐like cells represents a promising potential new therapy for treating heart disease, inducing significant improvements in postinfarct ventricular function in rodent models.
Vivek P. Singh, Megumi Mathison, Vivekkumar Patel, Deepthi Sanagasetti, Brian W. Gibson, Jianchang Yang, Todd K. Rosengart   +6 more
doaj   +1 more source

Efficiency of In Vivo Embryo Production following Superovulation with Sex-soted Semen in Hanwoo (Korean Native Cattle)

Journal of Animal Reproduction and Biotechnology, 2014
Sexed semen is commonly used for the production of calves of the desired gender. Gender selection is important in animal production industries. For example, female cattle are required for the dairy industry while males are preferred in the beef cattle ...
Hyang-A Jeon, Gyu-Tae Yeom, Hae-Geum Park, Sung-Woo Kim, Hyun Kim, Young Sin Seong, Hwan-Hoo Cho, Young Moo Cho, Jae-Hyeon Cho, Yeoung-Gyu Ko   +9 more
doaj   +1 more source

Studies on the Estimation of Pregnancy Rate of White Hanwoo (Albino Korean Native Cattle) with Sexed Semen

Journal of Animal Reproduction and Biotechnology, 2015
The purpose of this study is to produce wanted sex progeny of genetically confined White Hanwoo (albinism) with preselected sex sperm. One bull of White Hanwoo was chosen for semen donor and X sperm was sorted by MoFlo XDP cell sorter.
Sung Woo Kim, Jinseok Choi, Changyoung Choe, Dongkyo Kim, Yeoung-Gyu Ko, Chungsil So, Hwan-Hoo Seong   +6 more
doaj   +1 more source

miR-590-3p Overexpression Improves the Efficacy of hiPSC-CMs for Myocardial Repair

JACC: Basic to Translational Science
Summary: Recent evidence demonstrates that low engraftment rates limit the efficacy of human induced pluripotent stem cell–derived cardiomyocytes (hiPSC-CMs) for cardiac repair after myocardial infarction.
Zhiwei Zhang, MD, Xiaoting Li, MD, Jiawei Zhuang, MD, Qingwei Ding, MD, Hui Zheng, MD, Teng Ma, MD, Qingyou Meng, MD, Ling Gao, PhD   +7 more
doaj   +1 more source

Role of lncRNA TPRG1-AS1 in the development of cervical squamous cell carcinoma and its prognostic value

Discover Oncology
Objective Cervical squamous cell carcinoma (CSCC) has a poor prognosis due to persistent HPV infection. LncRNA TPRG1-AS1 is linked to regulating the development of many cancers, so the regulatory mechanism and prognostic value of TPRG1-AS1 in CSCC were ...
Yang Fan, Lan Ye, Shuyu Wang, Junwei Wang, Ke Wang, Ying Li   +5 more
doaj   +1 more source

Puckering effects of 4-hydroxy-l-proline isomers on the conformation of ornithine-free Gramicidin S

Acta Crystallographica Section E: Crystallographic Communications
The cyclic peptide cyclo(Val-Leu-Leu-D-Phe-Pro)2 (peptide 1) was specifically designed for structural chemistry investigations, drawing inspiration from Gramicidin S (GS).
Akiko Asano, Kanako Nakayama, Sakura Okada, Takuma Kato, Mitsunobu Doi   +4 more
doaj   +1 more source

Markarian 590: the AGN awakens

Monthly Notices of the Royal Astronomical Society: Letters
ABSTRACT Changing-look active galactic nucleus Mkn 590 recently underwent a sudden ‘re-ignition’, marked by substantial increases in optical/ultravilolet (UV) and X-ray continuum flux since last couple of years. Swift-XRT observations revealed the re-emergence of a soft X-ray excess as the source transitioned from a low-flux state in ...
Biswaraj Palit, Marzena Śniegowska, Alex Markowitz, Agata Różańska, Joseph Farah, D Andrew Howell   +5 more
openaire   +2 more sources

The Safety of Alcaligenes Lipid A in a Virus-Induced Immune Disease Model Associated with IgA, Th17 Cells, and Microbiota

Viruses
Lipid A is a component of lipopolysaccharide (LPS) of Gram-negative bacteria. Previously, we demonstrated that synthesized lipid A derived from Alcaligenes faecalis (ALA) could enhance antigen-specific immunoglobulin (Ig) A and T helper (Th) 17 responses,
Ijaz Ahmad, Seiichi Omura, Sundar Khadka, Fumitaka Sato, Ah-Mee Park, Cong Thanh Nguyen, Sandesh Rimal, Koichi Fukase, Atsushi Shimoyama, Ikuo Tsunoda   +9 more
doaj   +1 more source

Compassion Fatigue in Portuguese Firefighters: Preliminary Results of the Compassion Fatigue Scale

Medical Sciences Forum
The present study had the purpose of creating and studying the psychometric properties of the Compassion Fatigue Scale (CFS) in a sample of 286 firefighters, 69% of whom were males and 78% had previous exposure to a limit situation. All participants were
Lucas Sousa, Joana Antunes, Bruna Dias, Adriana Coelho, Karolina Costa, Andreia Conceição, Marina Carvalho, Carla Tomás, Mária Viegas   +8 more
doaj   +1 more source

Prognostic value of circ_0000043/miR-590-5p in cervical cancer and regulation of tumor progression

Discover Oncology
Objective To investigate the prognostic value of circ_0000043 in cervical cancer (CC) and its involvement in the modulation of patients’ prognostic progression.
Yue Zhu, Xi Shi, Shanshan Zhang, Hongyin Cui, Baohua Wu   +4 more
doaj   +1 more source