Results 11 to 20 of about 1,318,093 (377)
590. Recombinant Adenovirus Vaccines Against Anthrax [PDF]
Anthrax, the disease caused by Bacillus anthracis, is highly lethal and has emerged as a serious bioterrorism threat. A vaccine exists, however it requires six doses over eighteen months plus yearly boosts. Furthermore, the vaccine is made from the culture supernatant of an attenuated strain of B.
Michael J. Imperiale +1 more
openaire +3 more sources
Prognostic value of circ_0000043/miR-590-5p in cervical cancer and regulation of tumor progression [PDF]
Objective To investigate the prognostic value of circ_0000043 in cervical cancer (CC) and its involvement in the modulation of patients’ prognostic progression.
Yue Zhu +4 more
doaj +2 more sources
The phase 3 KEYNOTE-590 (NCT03189719) study showed first-line pembrolizumab plus chemotherapy significantly prolonged overall survival and progression-free survival versus placebo plus chemotherapy in patients with advanced unresectable or metastatic ...
T. Kojima +15 more
semanticscholar +1 more source
Melasma is a common refractory acquired pigmentary skin disease that mainly affects middle-aged women. The pathogenesis of melasma is still uncertain, while abnormal vascular endothelial cells may play a role.
Xiaoxi Dai +8 more
semanticscholar +1 more source
Accumulating evidence has indicated that Complement factor H-related 3 (CFHR3) plays an essential role in various diseases. However, the biological functions of CFHR3 in hepatocellular carcinoma (HCC) remain largely unclear.
Zhongzhong Wan +5 more
semanticscholar +1 more source
Background: Acute kidney injury (AKI) is a common complication in patients, especially elderly patients, who undergo cardiac surgery with cardiopulmonary bypass. Studies have indicated a protective role of autophagy in AKI.
Yimeng Chen +7 more
semanticscholar +1 more source
A Conversation with 590 Nascent Entrepreneurs [PDF]
This paper summarizes interviews from 1998 with 590 individuals trying to create a business centered around five questions: "Who are you?," "What are you trying to accomplish?," "What have you and others put into the business?," "What have you accomplished?," "What remains to be done?" There is a great deal of heterogeneity across these Nascent ...
Mariacristina De Nardi +3 more
openaire +4 more sources
miR-590–5p: A double-edged sword in the oncogenesis process
Accumulating evidence suggests the critical role of miR-590–5p in various aspects of cellular homeostasis, including cancer. Furthermore, we and others have recently demonstrated that miRNA-590–5p acts as an oncogene in some cancers while it acts as a ...
Tushar Singh Barwal +12 more
doaj +1 more source
Colorectal cancer (CRC) is a prevalent malignancy worldwide. The development of genome sequencing technology has allowed the discovery that epigenetic regulation might play a critical role in CRC tumorigenesis.
Zhongyi Zhou +6 more
semanticscholar +1 more source
MicroRNA-590 Inhibits Lipoprotein Lipase Expression and Prevents Atherosclerosis in apoE Knockout Mice. [PDF]
Recent studies have suggested that miR-590 may play critical roles in cardiovascular disease. This study was designed to determine the effects of miR-590 on lipoprotein lipase (LPL) expression and development of atherosclerosis in apolipoprotein E ...
Ping-Ping He +19 more
doaj +1 more source

