Results 11 to 20 of about 1,329,303 (325)

Long non‐coding RNA ESCCAL‐1/miR‐590/LRP6 signaling pathway participates in the progression of esophageal squamous cell carcinoma

open access: yesCancer Medicine, 2023
Background Long non‐coding RNAs (lncRNAs) have critical functions within esophageal squamous cell carcinoma (ESCC). However, the function and mechanism underlying ESCC‐associated lncRNA‐1 (ESCCAL‐1) in ESCC tumorigenesis have not been well clarified ...
Hongya Guan   +8 more
doaj   +1 more source

MiR-590 Suppresses Proliferation and Induces Apoptosis in Pancreatic Cancer by Targeting High Mobility Group A2

open access: yesTechnology in Cancer Research & Treatment, 2020
Background: Pancreatic ductal adenocarcinoma is a common malignancy with high morbidity. MicroRNAs have been demonstrated to be critical posttranscriptional regulators in tumorigenesis.
Ya-Dong Wang MD   +3 more
doaj   +1 more source

Circ_0124644 Serves as a ceRNA for miR-590-3p to Promote Hypoxia-Induced Cardiomyocytes Injury via Regulating SOX4

open access: yesFrontiers in Genetics, 2021
Circular RNA (circRNA) is an important factor for regulating the progression of many cardiovascular diseases, including acute myocardial infarction (AMI). However, the role of circ_0124644 in AMI progression remains unclear.
Juan Tan   +7 more
doaj   +1 more source

Functional role and epithelial to mesenchymal transition of the miR-590-3p/MDM2 axis in hepatocellular carcinoma

open access: yesBMC Cancer, 2023
Background There is considerable evidence that microRNAs (miRNAs) regulate several key tumor-associated genes/pathways and may themselves have a dual regulatory function either as tumor suppressors or oncogenic miRNA, depending on the tumor type ...
Alaa Ibrahem Youssef   +2 more
doaj   +1 more source

The miR-590/Acvr2a/Terf1 Axis Regulates Telomere Elongation and Pluripotency of Mouse iPSCs

open access: yesStem Cell Reports, 2018
Summary: During reprogramming, telomere re-elongation is important for pluripotency acquisition and ensures the high quality of induced pluripotent stem cells (iPSCs), but the regulatory mechanism remains largely unknown.
Qidong Liu   +10 more
doaj   +1 more source

LncRNA ZEB1-AS1 knockdown alleviates oxidative low-density lipoprotein-induced endothelial cell injury via the miR-590-5p/ HDAC9 axis

open access: yesCentral European Journal of Immunology, 2021
Oxidative low-density lipoprotein (ox-LDL) is thought to induce vascular endothelial cell injury, which contributes to the aetiopathogenesis of atherosclerosis (AS).
Jinpeng Zhong   +7 more
doaj   +1 more source

Assessing chronic rhinosinusitis with nasal polyps severity by “Japanese epidemiological survey of refractory eosinophilic chronic rhinosinusitis” algorithm [PDF]

open access: yesExploration of Asthma & Allergy, 2023
Aim: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complex disease with different subtypes that affect patients’ quality of life. This study aim to evaluate the severity of CRSwNP and the risk of treatment resistance using the “Japanese ...
Sérgio Duarte Dortas Jr   +7 more
doaj   +1 more source

Inhibiting ubiquitin conjugating enzyme E2 N by microRNA‐590‐3p reduced cell growth of cervical carcinoma

open access: yesKaohsiung Journal of Medical Sciences, 2020
The ubiquitin conjugating enzyme E2 N (UBE2N) has been reported to be involved in the tumorigenesis of several tumors, but its function in cervical carcinoma has not been investigated yet.
Ting‐Ting Song, Fei Xu, Wei Wang
doaj   +1 more source

The lncRNA PVT1/miR-590-5p/FSTL1 axis modulates the proliferation and migration of airway smooth muscle cells in asthma

open access: yesAutoimmunity, 2021
Objective Asthma is a prevalent chronic inflammatory airway disease that is characterised by airway remodelling and airway hyperresponsiveness. Abnormal proliferation and migration of airway smooth muscle cells (ASMCs) contribute to airway remodelling in
Wen-Lan Wang   +5 more
doaj   +1 more source

Exosomal miR-590-3p derived from cancer-associated fibroblasts confers radioresistance in colorectal cancer

open access: yesMolecular Therapy: Nucleic Acids, 2021
Radiotherapeutic resistance is a major obstacle for the effective treatment of colorectal cancer (CRC). MicroRNAs (miRNAs) play a critical role in chemoresistance and radioresistance.
Xijuan Chen   +7 more
doaj   +1 more source

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