Results 11 to 20 of about 1,270,133 (397)

A Conversation with 590 Nascent Entrepreneurs [PDF]

open access: yesSSRN Electronic Journal, 2007
This paper summarizes interviews from 1998 with 590 individuals trying to create a business centered around five questions: "Who are you?," "What are you trying to accomplish?," "What have you and others put into the business?," "What have you accomplished?," "What remains to be done?" There is a great deal of heterogeneity across these Nascent ...
Mariacristina De Nardi   +3 more
openaire   +6 more sources

AGN Type-casting: Mrk 590 No Longer Fits the Role [PDF]

open access: yes, 2014
We present multi-wavelength observations that trace more than 40 years in the life of the active galactic nucleus (AGN) in Mrk 590, traditionally known as a classic Seyfert 1 galaxy. From spectra recently obtained from HST, Chandra, and the Large Binocular Telescope, we find that the activity in the nucleus of Mrk 590 has diminished so significantly ...
Bentz, M. C.   +11 more
arxiv   +3 more sources

Role of lncRNA TPRG1-AS1 in the development of cervical squamous cell carcinoma and its prognostic value [PDF]

open access: yesDiscover Oncology
Objective Cervical squamous cell carcinoma (CSCC) has a poor prognosis due to persistent HPV infection. LncRNA TPRG1-AS1 is linked to regulating the development of many cancers, so the regulatory mechanism and prognostic value of TPRG1-AS1 in CSCC were ...
Yang Fan   +5 more
doaj   +2 more sources

Linc02381 Exacerbates Rheumatoid Arthritis Through Adsorbing miR-590-5p and Activating the Mitogen-Activated Protein Kinase Signaling Pathway in Rheumatoid arthritis-fibroblast-like synoviocytes

open access: yesCell Transplantation, 2020
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease. New evidence suggested that linc02381 suppressed colorectal cancer progression by regulating PI3 K signaling pathway, but the role of linc02381 in other diseases, such as RA, remains ...
Jing Wang, Qing Zhao
doaj   +2 more sources

590. Recombinant Adenovirus Vaccines Against Anthrax [PDF]

open access: hybridMolecular Therapy, 2006
Anthrax, the disease caused by Bacillus anthracis, is highly lethal and has emerged as a serious bioterrorism threat. A vaccine exists, however it requires six doses over eighteen months plus yearly boosts. Furthermore, the vaccine is made from the culture supernatant of an attenuated strain of B.
Michael J. McConnell   +1 more
openalex   +3 more sources

Markarian 590: The AGN Awakens [PDF]

open access: yesarXiv
Changing-Look AGN (CLAGN) Mkn 590 recently underwent a sudden re-ignition, marked by substantial increases in optical/UV and X-ray continuum flux since last couple of years. Swift-XRT observations revealed the re-emergence of a soft X-ray excess (SXE) as the source transitioned from a low-flux state in July 2023 to a significantly higher flux state in ...
Palit, Biswaraj   +5 more
arxiv   +2 more sources

MicroRNA-590 Inhibits Lipoprotein Lipase Expression and Prevents Atherosclerosis in apoE Knockout Mice. [PDF]

open access: yesPLoS ONE, 2015
Recent studies have suggested that miR-590 may play critical roles in cardiovascular disease. This study was designed to determine the effects of miR-590 on lipoprotein lipase (LPL) expression and development of atherosclerosis in apolipoprotein E ...
Ping-Ping He   +19 more
doaj   +1 more source

lncRNA SNHG4 modulates colorectal cancer cell cycle and cell proliferation through regulating miR-590-3p/CDK1 axis

open access: yesAging, 2021
Colorectal cancer (CRC) is a prevalent malignancy worldwide. The development of genome sequencing technology has allowed the discovery that epigenetic regulation might play a critical role in CRC tumorigenesis.
Zhongyi Zhou   +6 more
semanticscholar   +1 more source

Rutin attenuates Sorafenib-induced Chemoresistance and Autophagy in Hepatocellular Carcinoma by regulating BANCR/miRNA-590-5P/OLR1 Axis

open access: yesInternational Journal on Biological Sciences, 2021
Rutin, the main component of Potentilla discolor Bunge, was proven to exhibit anti-tumor properties. Sorafenib (SO) is conventionally used in chemotherapy against hepatocellular carcinoma (HCC), but acquired resistance developed during long-term therapy ...
Meng Zhou   +7 more
semanticscholar   +1 more source

CircPUM1 promotes cell growth and glycolysis in NSCLC via up-regulating METTL3 expression through miR-590-5p

open access: yesCell Cycle, 2021
RNA pumilio RNA binding family member 1 (circPUM1) has been reported to play important roles in the tumorigenesis of several cancers. However, the underlying molecular role of circPUM1 in non-small cell lung cancer (NSCLC) progression remains unknown ...
Mingjun Li   +4 more
semanticscholar   +1 more source

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