Results 11 to 20 of about 1,270,133 (397)
A Conversation with 590 Nascent Entrepreneurs [PDF]
This paper summarizes interviews from 1998 with 590 individuals trying to create a business centered around five questions: "Who are you?," "What are you trying to accomplish?," "What have you and others put into the business?," "What have you accomplished?," "What remains to be done?" There is a great deal of heterogeneity across these Nascent ...
Mariacristina De Nardi+3 more
openaire +6 more sources
AGN Type-casting: Mrk 590 No Longer Fits the Role [PDF]
We present multi-wavelength observations that trace more than 40 years in the life of the active galactic nucleus (AGN) in Mrk 590, traditionally known as a classic Seyfert 1 galaxy. From spectra recently obtained from HST, Chandra, and the Large Binocular Telescope, we find that the activity in the nucleus of Mrk 590 has diminished so significantly ...
Bentz, M. C.+11 more
arxiv +3 more sources
Role of lncRNA TPRG1-AS1 in the development of cervical squamous cell carcinoma and its prognostic value [PDF]
Objective Cervical squamous cell carcinoma (CSCC) has a poor prognosis due to persistent HPV infection. LncRNA TPRG1-AS1 is linked to regulating the development of many cancers, so the regulatory mechanism and prognostic value of TPRG1-AS1 in CSCC were ...
Yang Fan+5 more
doaj +2 more sources
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease. New evidence suggested that linc02381 suppressed colorectal cancer progression by regulating PI3 K signaling pathway, but the role of linc02381 in other diseases, such as RA, remains ...
Jing Wang, Qing Zhao
doaj +2 more sources
590. Recombinant Adenovirus Vaccines Against Anthrax [PDF]
Anthrax, the disease caused by Bacillus anthracis, is highly lethal and has emerged as a serious bioterrorism threat. A vaccine exists, however it requires six doses over eighteen months plus yearly boosts. Furthermore, the vaccine is made from the culture supernatant of an attenuated strain of B.
Michael J. McConnell+1 more
openalex +3 more sources
Markarian 590: The AGN Awakens [PDF]
Changing-Look AGN (CLAGN) Mkn 590 recently underwent a sudden re-ignition, marked by substantial increases in optical/UV and X-ray continuum flux since last couple of years. Swift-XRT observations revealed the re-emergence of a soft X-ray excess (SXE) as the source transitioned from a low-flux state in July 2023 to a significantly higher flux state in ...
Palit, Biswaraj+5 more
arxiv +2 more sources
MicroRNA-590 Inhibits Lipoprotein Lipase Expression and Prevents Atherosclerosis in apoE Knockout Mice. [PDF]
Recent studies have suggested that miR-590 may play critical roles in cardiovascular disease. This study was designed to determine the effects of miR-590 on lipoprotein lipase (LPL) expression and development of atherosclerosis in apolipoprotein E ...
Ping-Ping He+19 more
doaj +1 more source
Colorectal cancer (CRC) is a prevalent malignancy worldwide. The development of genome sequencing technology has allowed the discovery that epigenetic regulation might play a critical role in CRC tumorigenesis.
Zhongyi Zhou+6 more
semanticscholar +1 more source
Rutin, the main component of Potentilla discolor Bunge, was proven to exhibit anti-tumor properties. Sorafenib (SO) is conventionally used in chemotherapy against hepatocellular carcinoma (HCC), but acquired resistance developed during long-term therapy ...
Meng Zhou+7 more
semanticscholar +1 more source
RNA pumilio RNA binding family member 1 (circPUM1) has been reported to play important roles in the tumorigenesis of several cancers. However, the underlying molecular role of circPUM1 in non-small cell lung cancer (NSCLC) progression remains unknown ...
Mingjun Li+4 more
semanticscholar +1 more source