Results 11 to 20 of about 1,318,093 (377)

590. Recombinant Adenovirus Vaccines Against Anthrax [PDF]

open access: hybridMolecular Therapy, 2006
Anthrax, the disease caused by Bacillus anthracis, is highly lethal and has emerged as a serious bioterrorism threat. A vaccine exists, however it requires six doses over eighteen months plus yearly boosts. Furthermore, the vaccine is made from the culture supernatant of an attenuated strain of B.
Michael J. Imperiale   +1 more
openaire   +3 more sources

Prognostic value of circ_0000043/miR-590-5p in cervical cancer and regulation of tumor progression [PDF]

open access: yesDiscover Oncology
Objective To investigate the prognostic value of circ_0000043 in cervical cancer (CC) and its involvement in the modulation of patients’ prognostic progression.
Yue Zhu   +4 more
doaj   +2 more sources

First-line pembrolizumab + chemotherapy in Japanese patients with advanced/metastatic esophageal cancer from KEYNOTE-590

open access: yesEsophagus, 2022
The phase 3 KEYNOTE-590 (NCT03189719) study showed first-line pembrolizumab plus chemotherapy significantly prolonged overall survival and progression-free survival versus placebo plus chemotherapy in patients with advanced unresectable or metastatic ...
T. Kojima   +15 more
semanticscholar   +1 more source

590 nm LED Irradiation Improved Erythema through Inhibiting Angiogenesis of Human Microvascular Endothelial Cells and Ameliorated Pigmentation in Melasma

open access: yesCells, 2022
Melasma is a common refractory acquired pigmentary skin disease that mainly affects middle-aged women. The pathogenesis of melasma is still uncertain, while abnormal vascular endothelial cells may play a role.
Xiaoxi Dai   +8 more
semanticscholar   +1 more source

The miR-590-3p/CFHR3/STAT3 signaling pathway promotes cell proliferation and metastasis in hepatocellular carcinoma

open access: yesAging, 2022
Accumulating evidence has indicated that Complement factor H-related 3 (CFHR3) plays an essential role in various diseases. However, the biological functions of CFHR3 in hepatocellular carcinoma (HCC) remain largely unclear.
Zhongzhong Wan   +5 more
semanticscholar   +1 more source

Exosomal transfer of microRNA-590-3p between renal tubular epithelial cells after renal ischemia-reperfusion injury regulates autophagy by targeting TRAF6

open access: yesChinese Medical Journal, 2022
Background: Acute kidney injury (AKI) is a common complication in patients, especially elderly patients, who undergo cardiac surgery with cardiopulmonary bypass. Studies have indicated a protective role of autophagy in AKI.
Yimeng Chen   +7 more
semanticscholar   +1 more source

A Conversation with 590 Nascent Entrepreneurs [PDF]

open access: yesSSRN Electronic Journal, 2007
This paper summarizes interviews from 1998 with 590 individuals trying to create a business centered around five questions: "Who are you?," "What are you trying to accomplish?," "What have you and others put into the business?," "What have you accomplished?," "What remains to be done?" There is a great deal of heterogeneity across these Nascent ...
Mariacristina De Nardi   +3 more
openaire   +4 more sources

miR-590–5p: A double-edged sword in the oncogenesis process

open access: yesCancer Treatment and Research Communications, 2022
Accumulating evidence suggests the critical role of miR-590–5p in various aspects of cellular homeostasis, including cancer. Furthermore, we and others have recently demonstrated that miRNA-590–5p acts as an oncogene in some cancers while it acts as a ...
Tushar Singh Barwal   +12 more
doaj   +1 more source

lncRNA SNHG4 modulates colorectal cancer cell cycle and cell proliferation through regulating miR-590-3p/CDK1 axis

open access: yesAging, 2021
Colorectal cancer (CRC) is a prevalent malignancy worldwide. The development of genome sequencing technology has allowed the discovery that epigenetic regulation might play a critical role in CRC tumorigenesis.
Zhongyi Zhou   +6 more
semanticscholar   +1 more source

MicroRNA-590 Inhibits Lipoprotein Lipase Expression and Prevents Atherosclerosis in apoE Knockout Mice. [PDF]

open access: yesPLoS ONE, 2015
Recent studies have suggested that miR-590 may play critical roles in cardiovascular disease. This study was designed to determine the effects of miR-590 on lipoprotein lipase (LPL) expression and development of atherosclerosis in apolipoprotein E ...
Ping-Ping He   +19 more
doaj   +1 more source

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