Results 11 to 20 of about 1,350,327 (326)

Linc02381 Exacerbates Rheumatoid Arthritis Through Adsorbing miR-590-5p and Activating the Mitogen-Activated Protein Kinase Signaling Pathway in Rheumatoid arthritis-fibroblast-like synoviocytes

Cell Transplantation, 2020
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease. New evidence suggested that linc02381 suppressed colorectal cancer progression by regulating PI3 K signaling pathway, but the role of linc02381 in other diseases, such as RA, remains ...
Jing Wang, Qing Zhao
doaj   +2 more sources

Prognostic value of circ_0000043/miR-590-5p in cervical cancer and regulation of tumor progression [PDF]

Discover Oncology
Objective To investigate the prognostic value of circ_0000043 in cervical cancer (CC) and its involvement in the modulation of patients’ prognostic progression.
Yue Zhu, Xi Shi, Shanshan Zhang, Hongyin Cui, Baohua Wu   +4 more
doaj   +2 more sources

590 nm LED Irradiation Improved Erythema through Inhibiting Angiogenesis of Human Microvascular Endothelial Cells and Ameliorated Pigmentation in Melasma

Cells, 2022
Melasma is a common refractory acquired pigmentary skin disease that mainly affects middle-aged women. The pathogenesis of melasma is still uncertain, while abnormal vascular endothelial cells may play a role.
Xiaoxi Dai, Shanglin Jin, Y. Xuan, Yiwen Yang, Xiaoli Lu, Chen Wang, Li Chen, L. Xiang, Chengfeng Zhang   +8 more
semanticscholar   +1 more source

First-line pembrolizumab + chemotherapy in Japanese patients with advanced/metastatic esophageal cancer from KEYNOTE-590

Esophagus, 2022
The phase 3 KEYNOTE-590 (NCT03189719) study showed first-line pembrolizumab plus chemotherapy significantly prolonged overall survival and progression-free survival versus placebo plus chemotherapy in patients with advanced unresectable or metastatic ...
T. Kojima, H. Hara, A. Tsuji, H. Yasui, K. Muro, T. Satoh, T. Ogata, R. Ishihara, M. Goto, Hideo Baba, T. Nishina, S. Han, Tomoko Sakata, Naoyoshi Yatsuzuka, T. Doi, Ken Kato   +15 more
semanticscholar   +1 more source

The miR-590-3p/CFHR3/STAT3 signaling pathway promotes cell proliferation and metastasis in hepatocellular carcinoma

Aging, 2022
Accumulating evidence has indicated that Complement factor H-related 3 (CFHR3) plays an essential role in various diseases. However, the biological functions of CFHR3 in hepatocellular carcinoma (HCC) remain largely unclear.
Zhongzhong Wan, Xingrun Li, Xinru Luo, Bofan Wang, Xiaoping Zhou, Ao Chen   +5 more
semanticscholar   +1 more source

MicroRNA-590 Inhibits Lipoprotein Lipase Expression and Prevents Atherosclerosis in apoE Knockout Mice. [PDF]

PLoS ONE, 2015
Recent studies have suggested that miR-590 may play critical roles in cardiovascular disease. This study was designed to determine the effects of miR-590 on lipoprotein lipase (LPL) expression and development of atherosclerosis in apolipoprotein E ...
Ping-Ping He, Xin-Ping OuYang, Yuan Li, Yun-Cheng Lv, Zong-Bao Wang, Feng Yao, Wei Xie, Yu-Lin Tan, Liang Li, Min Zhang, Gang Lan, Duo Gong, Hai-Peng Cheng, Hui-Juan Zhong, Dan Liu, Chong Huang, Zhao-Xia Li, Xi-Long Zheng, Wei-Dong Yin, Chao-Ke Tang   +19 more
doaj   +1 more source

miR-590–5p: A double-edged sword in the oncogenesis process

Cancer Treatment and Research Communications, 2022
Accumulating evidence suggests the critical role of miR-590–5p in various aspects of cellular homeostasis, including cancer. Furthermore, we and others have recently demonstrated that miRNA-590–5p acts as an oncogene in some cancers while it acts as a ...
Tushar Singh Barwal, Neha Singh, Uttam Sharma, Sonali Bazala, Medha Rani, Alisha Behera, Ram Kumar Kumawat, Pawan Kumar, Vivek Uttam, Akanksha Khandelwal, Jyoti Barwal, Manju Jain, Aklank Jain   +12 more
doaj   +1 more source

lncRNA SNHG4 modulates colorectal cancer cell cycle and cell proliferation through regulating miR-590-3p/CDK1 axis

Aging, 2021
Colorectal cancer (CRC) is a prevalent malignancy worldwide. The development of genome sequencing technology has allowed the discovery that epigenetic regulation might play a critical role in CRC tumorigenesis.
Zhongyi Zhou, Fengbo Tan, Q. Pei, Chenglong Li, Yuanquan Zhou, Yuqiang Li, Haiping Pei   +6 more
semanticscholar   +1 more source

Exosomal transfer of microRNA-590-3p between renal tubular epithelial cells after renal ischemia-reperfusion injury regulates autophagy by targeting TRAF6

Chinese Medical Journal, 2022
Background: Acute kidney injury (AKI) is a common complication in patients, especially elderly patients, who undergo cardiac surgery with cardiopulmonary bypass. Studies have indicated a protective role of autophagy in AKI.
Yimeng Chen, Congya Zhang, Yingjie Du, Xiying Yang, Min Liu, W. Yang, G. Lei, Guyan Wang   +7 more
semanticscholar   +1 more source

Khosrow II (590–628 CE)

Encyclopedia, 2022
Khosrow II (r. 590–628 CE) was the last great Sasanian king who took the throne with the help of the Romans and broke with dynastic religious preferences as he became married to a Christian empress.
Mahdi Motamedmanesh, Samira Royan
doaj   +1 more source