Results 21 to 30 of about 243,130 (240)

The miR-590/Acvr2a/Terf1 Axis Regulates Telomere Elongation and Pluripotency of Mouse iPSCs

open access: yesStem Cell Reports, 2018
Summary: During reprogramming, telomere re-elongation is important for pluripotency acquisition and ensures the high quality of induced pluripotent stem cells (iPSCs), but the regulatory mechanism remains largely unknown.
Qidong Liu   +10 more
doaj   +1 more source

LncRNA ZEB1-AS1 knockdown alleviates oxidative low-density lipoprotein-induced endothelial cell injury via the miR-590-5p/ HDAC9 axis

open access: yesCentral European Journal of Immunology, 2021
Oxidative low-density lipoprotein (ox-LDL) is thought to induce vascular endothelial cell injury, which contributes to the aetiopathogenesis of atherosclerosis (AS).
Jinpeng Zhong   +7 more
doaj   +1 more source

Assessing chronic rhinosinusitis with nasal polyps severity by “Japanese epidemiological survey of refractory eosinophilic chronic rhinosinusitis” algorithm [PDF]

open access: yesExploration of Asthma & Allergy, 2023
Aim: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complex disease with different subtypes that affect patients’ quality of life. This study aim to evaluate the severity of CRSwNP and the risk of treatment resistance using the “Japanese ...
Sérgio Duarte Dortas Jr   +7 more
doaj   +1 more source

Inhibiting ubiquitin conjugating enzyme E2 N by microRNA‐590‐3p reduced cell growth of cervical carcinoma

open access: yesKaohsiung Journal of Medical Sciences, 2020
The ubiquitin conjugating enzyme E2 N (UBE2N) has been reported to be involved in the tumorigenesis of several tumors, but its function in cervical carcinoma has not been investigated yet.
Ting‐Ting Song, Fei Xu, Wei Wang
doaj   +1 more source

The lncRNA PVT1/miR-590-5p/FSTL1 axis modulates the proliferation and migration of airway smooth muscle cells in asthma

open access: yesAutoimmunity, 2021
Objective Asthma is a prevalent chronic inflammatory airway disease that is characterised by airway remodelling and airway hyperresponsiveness. Abnormal proliferation and migration of airway smooth muscle cells (ASMCs) contribute to airway remodelling in
Wen-Lan Wang   +5 more
doaj   +1 more source

Exosomal miR-590-3p derived from cancer-associated fibroblasts confers radioresistance in colorectal cancer

open access: yesMolecular Therapy: Nucleic Acids, 2021
Radiotherapeutic resistance is a major obstacle for the effective treatment of colorectal cancer (CRC). MicroRNAs (miRNAs) play a critical role in chemoresistance and radioresistance.
Xijuan Chen   +7 more
doaj   +1 more source

Selection of a Navigation Strategy According to Agricultural Scenarios and Sensor Data Integrity

open access: yesAgronomy, 2023
In digital farming, the use of technology to increase agricultural production through automated tasks has recently integrated the development of AgBots for more reliable data collection using autonomous navigation.
Leonardo Bonacini   +9 more
doaj   +1 more source

MiR-590-3p suppresses hepatocellular carcinoma growth by targeting TEAD1

open access: yesTumor Biology, 2017
MicroRNA signature is altered in different disease states including cancer, and some microRNAs act as oncogenes or tumor suppressors. MiR-590-3p has been shown to be involved in human cancer progression.
Xin Ge, Liansheng Gong
doaj   +1 more source

MiR-590-3p affects the function of adipose-derived stem cells (ADSCs) on the survival of skin flaps by targeting VEGFA

open access: yesRegenerative Therapy, 2022
Introduction: Partial necrosis of skin flaps is still a substantial problem in plastic and reconstructive surgery. In this study, the role of miR-590-3p in adipose-derived stem cells (ADSCs) transplantation in improving the survival of skin flap in a ...
Kai Yang   +7 more
doaj   +1 more source

Common miR-590 Variant rs6971711 Present Only in African Americans Reduces miR-590 Biogenesis.

open access: yesPLoS ONE, 2016
MicroRNAs (miRNAs) are recognized as important regulators of cardiac development, hypertrophy and fibrosis. Recent studies have demonstrated that genetic variations which cause alterations in miRNA:target interactions can lead to disease. We hypothesized
Xiaoping Lin   +15 more
doaj   +1 more source

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