Results 101 to 110 of about 9,551,377 (187)

Effect of 6-shogaol on viability and apoptosis in HCC cells.

, 2012
(A) The chemical structure of 6-shogaol. (B) SMMC-7721, BEL-7404 and HepG2 cells were treated with 5, 10, 15, 20, 25, 30, 40 and 50 µM 6-shogaol for 24 h respectively, and the cell viability was determined by MTT assay.
Yong-Bo Peng (153732), Xiaojun Xu (153741), Lei Zhang (38117), Qun Liu (67203), Xiao-Dong Wen (153765), Ning Gao (153779), Jiang Ma (153750), Lian-Wen Qi (153773), Rong Hu (153724), Ping Zhou (144535), Ping Li (31981)   +10 more
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6-Shogaol enhances the chemotherapeutic efficacy of 5-fluorouracil through apoptosis induction and cell cycle arrest in MCF-7 breast cancer cells

Pharmacological Research - Modern Chinese Medicine
Background: Ginger (Zingiber officinale) has a long history of use in Traditional Chinese Medicine (TCM) as a “cure-all remedy”. 6-Shogaol, an essential bioactive element from dried ginger, has been widely used in traditional Chinese medicinal ...
Pitchakorn Sangchang, Chanokbhorn Phaosiri, Gulsiri Senawong, Pakit Kumboonma, Narissara Namwan, Thanaset Senawong   +5 more
doaj   +1 more source

Identification and characterization of [6]-shogaol from ginger as inhibitor of vascular smooth muscle cell proliferation [PDF]

, 2015
Scope Vascular smooth muscle cell (VSMC) proliferation is involved in the pathogenesis of cardiovascular disease, making the identification of new counteracting agents and their mechanisms of action relevant.
N. Sider, B. Gröblacher, Rudolf Bauer, Dean Guo, Bucar, Franz, Gröblacher, Barbara, Dirsch, Verena, R. China, D. Guo, Rongxia Liu, Heiss, Elke, Atanasov, Atanas, Andreas Schinkovitz, E.H. Heiss, Guo, Dean, Verena M. Dirsch, Elke H. Heiss, Liu, Rongxia, Sider, Nadine, Bauer, Rudolf, Schinkovitz, Andreas, F. Bucar, V.M. Dirsch, R. Liu, Nadine Sider, R. Bauer, A.G. Atanasov, Franz Bucar, A. Schinkovitz, Barbara Gröblacher, Atanas G. Atanasov   +30 more
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Characteristics and thermodynamics of the interaction of 6-shogaol with human serum albumin as studied by isothermal titration calorimetry

Brazilian Journal of Pharmaceutical Sciences
The interaction between 6-shogaol, a pharmacologically active ginger constituent, and human serum albumin (HSA), the main in vivo drug transporter, was investigated using isothermal titration calorimetry (ITC). The value of the binding constant, Ka (5.02
Shevin Rizal Feroz, Sri Nurestri Abdul Malek, Saad Tayyab   +2 more
doaj   +1 more source

Data_Sheet_1_Antibiofilm and Antivirulence Activities of 6-Gingerol and 6-Shogaol Against Candida albicans Due to Hyphal Inhibition.doc

, 2018
Candida albicans is an opportunistic pathogen and responsible for candidiasis. C. albicans readily forms biofilms on various biotic and abiotic surfaces, and these biofilms can cause local and systemic infections. C.
Jae Gyu Park (1536442), Pilju Choi (1576513), Yong-Guy Kim (536298), Jin-Hyung Lee (471840), Jintae Lee (75817), Jungyeob Ham (26675)   +5 more
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Effect of the Ginger Derivative, 6-Shogaol, on Ferritin Levels in Patients With Low to Intermediate-1–Risk Myelodysplastic Syndrome—A Small, Investigative Study

Clinical Medicine Insights: Blood Disorders, 2017
Background: Myelodysplastic syndrome (MDS) is a heterogeneous group of clonal stem cell disorders characterized by dysplastic and ineffective hematopoiesis and peripheral cytopenias.
Terry Golombick, Terrence H Diamond, Arumugam Manoharan, Rajeev Ramakrishna, Vladimir Badmaev   +4 more
doaj   +1 more source

Albumin Nanoparticles Harness Activated Neutrophils to Cross Vascular Barriers for Targeted Subcutaneous and Orthotopic Colon Cancer Therapy

Journal of Functional Biomaterials
Colorectal cancer (CRC) therapy faces challenges due to limited drug penetration across the blood–tumor barrier. Neutrophils, with their natural ability to migrate to inflamed and tumor sites, offer a promising cell-mediated delivery strategy. This study
Zhifan Luo, Liuqing Dong, Yujie Zhang, Mingzhen Zhang   +3 more
doaj   +1 more source

Comparing the effects of microwave radiation on 6-gingerol and 6-shogaol from ginger rhizomes (Zingiber officinale Rosc).

PLoS ONE, 2019
The active component obtained from ginger is a high value-added product, but continued research is required for improved extraction techniques that will lead to better quality extracts and greater yields.
Hui Teng, Kemueli T Seuseu, Won-Young Lee, Lei Chen   +3 more
doaj   +1 more source

Inhibitory Effect of 6-Shogaol On Viability Of Tumor Cell Lines [PDF]

, 2019
Cancer remains a leading cause of death in the United States. Although chemotherapy and radiation therapy are being currently used to treat cancer, they have from detrimental side effects.
Mungre, Shubhangee M.
core   +1 more source

In vivo antitumor effects of 6-shogaol in SMMC-7721 xenografts.

, 2012
SCID mice were inoculated with SMMC-7721 cells (3×106 cells/mouse, s.c.) and randomly divided into three groups (8/group) treated with 6-shogaol (10 mg/kg and 50 mg/kg, i.p., daily) or vehicle control solvent.
Yong-Bo Peng (153732), Xiaojun Xu (153741), Lei Zhang (38117), Qun Liu (67203), Xiao-Dong Wen (153765), Ning Gao (153779), Jiang Ma (153750), Lian-Wen Qi (153773), Rong Hu (153724), Ping Zhou (144535), Ping Li (31981)   +10 more
core   +1 more source