Results 71 to 80 of about 7,966 (172)
Analytical Cellular Pathology, 2019 Aim. This study is aimed at investigating the effect of Shogaol, a phenolic constituent of ginger, on dextran sodium sulfate- (DSS-) induced ulcerative colitis (UC) in mice in comparison with 6-thioguanine (6-TG), an immune-suppressant chemotherapeutic ...
Snur M. A. Hassan, Ali Hussein Hassan
doaj +1 more source
Perforating dermatosis in a patient receiving azathioprine
Indian Journal of Dermatology, 2013 Azathioprine (AZA) is an imidazole derivative of mercaptopurine. It antagonizes purine metabolism, and it may inhibit synthesis of DNA, RNA, and proteins.
Emiliano Grillo +3 more
doaj +1 more source
Managing Ulcerative Colitis – The Guidelines and Beyond [PDF]
European Medical Journal Gastroenterology, 2013 Management guidelines offer clinicians clear, evidence-based and often succinct treatment advice. For ulcerative colitis these guidelines describe the use of 5-ASA, corticosteroids, thiopurines, cyclosporine, and anti-TNFα therapies.
Mitchell RKL Lie +1 more
doaj
A New Electrochemical Sensor for Direct Detection of Purine Antimetabolites and DNA Degradation
Journal of Analytical Methods in Chemistry, 2019 The development of a reliable electrochemical sensor using a hybrid nanocomposite consisting of ionic liquid (1-butyl-3-methylimidazolium hexafluorophosphate) functionalized graphene oxide (GrO-IL) and gold nanoparticles (AuNPs) stabilized by chitosan ...
Liliya K. Shpigun, Elena Yu. Andryukhina
doaj +1 more source
Suspected azathioprine induced liver cirrhosis: an unusual side effect
The Pan African Medical Journal, 2014 In recent years, the hepatotoxic potential of thiopurines, in particular 6-thioguanine (6-TG) has been discussed in literature. However, cirrhosis was exceptionally reported.
Aida Ben Slama Trabelsi +5 more
doaj +1 more source
BMC Neurology, 2017 Background Neuromyelitis optica spectrum disorders (NMOSD) are demyelinating autoimmune diseases in the central nervous system (CNS) that are characterized by a high relapse rate and the presence of anti-aquaporin 4 antibodies (AQP4-IgG) in the serum ...
Xindi Li +9 more
doaj +1 more source
The relationship between 6-thioguanine levels and remission outcomes in children with autoimmune hepatitis. Single center experience. [PDF]
Clin Exp Hepatol, 2023 Kaps-Kopiec D +7 more
europepmc +1 more source
Haematologica, 2004 13-cis retinoic acid + (OH)2 vitamin D3 + low-dose 6-thioguanine and cytarabine were tested in 26 patients with acute myeloid leukemia (AML) and in 4 patients with myelodysplastic syndrome (MDS) (median age 72.5), ineligible for standard chemotherapy ...
D Ferrero +5 more
doaj
Concomitant 5-aminosalicylic acid treatment does not affect 6-thioguanine nucleotide levels in patients with inflammatory bowel disease on thiopurines. [PDF]
Ann Gastroenterol, 2023 Looser R +7 more
europepmc +1 more source
Association between 6-thioguanine nucleotide levels and preventing production of antibodies to infliximab in patients with inflammatory bowel disease. [PDF]
BMJ Open Gastroenterol, 2023 Phillips J, Leary S, Tyrrell-Price J.
europepmc +1 more source