Results 21 to 30 of about 714 (114)
Testing for treatment effect twice using internal and external controls in clinical trials
Journal of Causal Inference, 2023 Leveraging external controls – relevant individual patient data under control from external trials or real-world data – has the potential to reduce the cost of randomized controlled trials (RCTs) while increasing the proportion of trial patients given ...
Yi Yanyao, Zhang Ying, Du Yu, Ye Ting
doaj +1 more source
Correlation between Animal and Mathematical Models for Prostate Cancer Progression
Computational and Mathematical Methods in Medicine, Volume 10, Issue 4, Page 241-252, 2009., 2009 This work demonstrates that prostate tumour progression in vivo can be analysed by using solutions of a mathematical model supplemented by initial conditions chosen according to growth rates of cell lines in vitro. The mathematical model is investigated and solved numerically.
Z. Jackiewicz +3 more
wiley +1 more source
Computational and Mathematical Methods in Medicine, Volume 7, Issue 1, Page 45-51, 2006., 2006 Meta‐analysis is a widely used tool to synthesize the results of a set of primary studies leading to more powerful conclusions than those provided by isolated ones. To evaluate the effect of allocated radiotherapy, types of breast surgery and other risk factors over death risk in early breast cancer patients, we carried out a meta‐analysis using ...
V. Alba-Fernández, N. Ruiz-Fuentes
wiley +1 more source
An Equilibrium Assembly Model Applied to Murine Polyomavirus
Computational and Mathematical Methods in Medicine, Volume 6, Issue 2, Page 91-93, 2005., 2005 In Keef et al., Assembly Models for Papovaviridae based on Tiling Theory (submitted to J. Phys. Biol.), 2005 [1] we extended an equilibrium assembly model to the (pseudo–)T = 7 viral capsids in the family of Papovaviridae providing assembly pathways for the most likely or primary intermediates and computing their concentrations.
T. Keef
wiley +1 more source
The Architecture of Viral Capsids Based on Tiling Theory
Computational and Mathematical Methods in Medicine, Volume 6, Issue 2, Page 87-90, 2005., 2005 A vital constituent of a virus is its protein shell, called the viral capsid, that encapsulates and hence protects the viral genome. The surface structures of a large number of icosahedral viruses can be modelled via Caspar‐Klug Theory, which has hence become one of the fundamental concepts in virology. However, growing experimental evidence have shown
R. Twarock
wiley +1 more source
On construction of the smallest one-sided confidence interval for the difference of two proportions [PDF]
, 2010 For any class of one-sided $1-\alpha$ confidence intervals with a certain monotonicity ordering on the random confidence limit, the smallest interval, in the sense of the set inclusion for the difference of two proportions of two independent binomial ...
Wang, Weizhen
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A Stochastic Model of Icosahedral Capsid Growth
Computational and Mathematical Methods in Medicine, Volume 6, Issue 2, Page 95-97, 2005., 2005 A model of growth of icosahedral capsids is proposed. It is similar to the stochastic model of fullerene growth, but takes into account variations in the composition of pentamers and hexamers that are responsible for the final capsid size. We show that the observed high yield of capsid production implies a high level of self‐organization of the ...
R. Kerner
wiley +1 more source
Segmentation of the Poisson and negative binomial rate models: a penalized estimator [PDF]
, 2013 We consider the segmentation problem of Poisson and negative binomial (i.e. overdispersed Poisson) rate distributions. In segmentation, an important issue remains the choice of the number of segments.
Cleynen, Alice, Lebarbier, Emilie
core +2 more sources
Analyzing high dimensional correlated data using feature ranking and classifiers
Computational and Mathematical Biophysics, 2019 The Illumina Infinium HumanMethylation27 (Illumina 27K) BeadChip assay is a relatively recent high-throughput technology that allows over 27,000 CpGs to be assayed.
Patil Abhijeet R +3 more
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Causal effect on a target population: A sensitivity analysis to handle missing covariates
Journal of Causal Inference, 2022 Randomized controlled trials (RCTs) are often considered the gold standard for estimating causal effect, but they may lack external validity when the population eligible to the RCT is substantially different from the target population.
Colnet Bénédicte +3 more
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