Results 91 to 100 of about 24,120 (173)

VASCULAR BARRIER DISRUPTION IN COHO SALMON (ONCORHYNCHUS KISUTCH) EXPOSED TO ROADWAY RUNOFF AND 6PPD-QUINONE [PDF]

Urban runoff mortality syndrome (URMS) causes rapid, recurrent mortality of coho salmon (Oncorhynchus kisutch) in urban watersheds of the Pacific Northwest.
Blair, Stephanie
core   +3 more sources

Emerging contaminants in stormwater: Tire-derived chemicals, pharmaceuticals, and heavy metals detected in a United Arab Emirates extreme weather event

Journal of Hazardous Materials Letters
Climate change is associated with the intensification of weather patterns, including extreme weather events of historically arid regions such as the United Arab Emirates (UAE). On April 16–17, 2024, the UAE experienced a severe storm with unusually heavy
Jonathan Navarro Ramos, Lara Dronjak, Sofian Kanan, Md Maruf Mortula, Joshua S. Wallace, Fatin Samara, Ning Dai, Diana S. Aga   +7 more
doaj   +1 more source

Targeting the PI3K-AKT pathway to alleviate 6PPDQ-induced cognitive impairment associated with metabolic syndrome

Ecotoxicology and Environmental Safety
6PPD-quinone (6PPDQ), a derivative of the antioxidant 6PPD used in the rubber industry, has been implicated in environmental and public health risks. To explore its impact on metabolic and cognitive functions, we orally administered 6PPDQ to mice and ...
Leisheng Wang, Yifei Fu, Shiwei Xu, Enhong Chen, Shuo Zhang, Dongjie Yang, Youzhao He, Yuanlong Gu, Yong Mao, Fenglai Yuan, Hao Hu   +10 more
doaj   +1 more source

Transformation pathways, detection, removal, and sustainable alternatives of 6PPD and its quinone derivative (6PPDQ): A comprehensive review

Emerging Contaminants
N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) is a widely used antioxidant and antiozonant in vehicle tires, commonly used to enhance rubber durability and performance. However, its environmental transformation, particularly into 6PPD-Quinone
Kavya Somepalli, Gangadhar Andaluri
doaj   +1 more source

Occurrence, Ecological Risk, and Human Exposure of Rubber Additives and Transformation Products in Surface Waters of Kaifeng, China

Toxics
This study investigated rubber additives and relevant transformation products (RARTPs) in surface waters of Kaifeng, a city linking the Yellow River and Huaihe River basins. Seven of fifteen target analytes were detected in >10% of samples.
Xing Chen, Chenyang Sun, Lingnan Du, Xinding Yao, Haifeng Wang, Zongwu Wang, Jiapu Ji, Jinting Huang   +7 more
doaj   +1 more source

Regioselective In Vitro Toxicity of Aromatic Hydroxylated Metabolites of 6PPD-Quinone

6PPD-Q undergoes rapid enzymatic reactions within salmonids to form two major hydroxylated metabolites, one alkyl and one aryl. While alkyl-OH-6PPD-Q has been confirmed to be nontoxic, the toxicity of aryl-OH-6PPD-Q remains unknown. We herein synthesized three aryl-OH-6PPD-Q isomers and tested their in vitro toxicity in a coho salmon (O.
Pranav Nair, Hannah Byun, Justin MacLeod, Maria Jose Gendron Romero, Linna Xie, Jianxian Sun, Datong Song, Hui Peng   +7 more
openaire   +1 more source

From exposure models to multi-organ toxicity of 6PPD-quinone in mice: A mini-review

Ecotoxicology and Environmental Safety
Emerging evidence positions 6PPD-quinone (6PPD-Q) as a global environmental contaminant, with confirmed toxicity to various species and widespread detection in human biological samples. Despite these observations, toxicological understanding of 6PPD-Q in mammals remains fragmented and inconsistent.
Meiling Yang, Qi Jing, Wenjie Zhang, Qi Wang, Lin Zhong, Yongshun Huang, Yiru Qin   +6 more
openaire   +2 more sources

Spatiotemporal distribution and environmental risk assessment of 6PPDQ in the Schuylkill River

Emerging Contaminants
Tire wear particles (TWPs) and associated contaminants, including microplastics, benzothiazoles, polycyclic aromatic hydrocarbons (PAHs), N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD), its byproduct 6PPD-Quinone (6PPDQ), and heavy metals, are
Kavya Somepalli, Gangadhar Andaluri
doaj   +1 more source

Oxidative stress generated DNA damage by 6PPD and other tyre additives in A549 human lung epithelial cells

Scientific Reports
Tyre additives such as p-phenylenediamines (PPDs) and benzothiazoles (BTs) are ubiquitous in the environment. They have been frequently detected in urban air and have been detected in the human body.
Samuel Hyman, Rea Bilić, Annie Jensen, Siriel Saladin, Yurii Tsybrii, Oleksii Nosko, David Topping, Adam Boies, Chiara Giorio, Martin Roursgaard, Peter Møller   +10 more
doaj   +1 more source

Urban pavements as sources and conduits of microbial, microplastic, and emerging contaminants in water systems: A critical review of mechanisms, pathways, and mitigation

H2Open Journal
Urban pavements act as reactive environmental interfaces, generating, retaining, and mobilizing pollutants, including microbial communities, microplastics, and emerging chemical contaminants. This critical review synthesizes 107 studies (2020–March 2026),
Adham Mohammed Alnadish, Sallahuddin Panhwar, Hareef Ahmed Keerio   +2 more
doaj   +1 more source