Results 121 to 130 of about 7,464,333 (166)

Synthesis of 7-dehydrocholesterol acetate

Chemistry of Natural Compounds, 1973
It has been shown that 7-oxocholesterol acetate (III) can easily be converted into 7-dehydrocholesterol acetate by the Bamford-Stevens reaction. The yield of desired product amounts to 79% calculated on the (III) or 63% calculated on the cholesterol acetate.
E. V. Yablonskaya, M. G. Segal
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The preparation of radioactive 7-dehydrocholesterol

Steroids, 1963
The preparation of radioactive 7-dehydrocholesterol (5,7-cholestadien-3 BETA -ol) by procedures that utilize milligram quantities of cholesterol as starting material is described. The isocaproate adaptation of the allylic bromination of cholesterol with N-bromosuccinimide followed by dehydrobromination was employed and found to be amenable to a scale ...
B.D. Kulkarni, G. Blondin, W.R. Nes
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HPLC analysis of desmosterol, 7‐dehydrocholesterol, and cholesterol

Lipids, 1989
AbstractA simple and sensitive method to analyzed mixtures of desmosterol, 7‐dehydrocholesterol and cholesterol is described. The method involves the oxidative conversion of the sterols with cholesterol oxidase, followed by high performance liquid chromatographic (HPLC) analysis.
E H, Goh, S M, Colles, K D, Otte
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The effects of 7-dehydrocholesterol on the structural properties of membranes

Physical Biology, 2011
Smith-Lemli-Opitz syndrome, a congenital and developmental malformation disease, is typified by abnormal accumulation of 7-dehydrocholesterol (7DHC), the immediate precursor of cholesterol (CHOL), and depletion thereof. Knowledge of the effect of 7DHC on the biological membrane is, however, still fragmentary.
Yingzhe, Liu, Christophe, Chipot, Xueguang, Shao, Wensheng, Cai   +3 more
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Photometabolism of 7-dehydrocholesterol to previtamin D3 in skin

Biochemical and Biophysical Research Communications, 1977
Abstract The photometabolism of [3α-3H]-7-dehydrocholesterol in skin was studied in groups of rats exposed to ultraviolet irradiation. The major photolytic product was identified as previtamin D3 by its identical migration with authentic previtamin D3 on high-pressure liquid chromatography.
M F, Holick, J E, Frommer, S C, McNeill, N M, Richtand, J W, Henley, J T, Potts   +5 more
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Light‐Induced Activation of 7‐Dehydrocholesterol

Angewandte Chemie International Edition in English, 1982
AbstractThe complete manuscript of this communication appears in: Angew. Chem. Suppl. 1982, 846.
Karlheinz Schmitt‐Rau, Manfred Wilk
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Occurrence of 7-dehydrocholesterol in the uropygial gland of domestic fowls

Acta Histochemica, 1978
Histochemical studies on the uropygial gland of domestic fowls have shown the presence of sterols (among which cholesterol and its esters) in the lipidic fraction of the gland secret. beta-Glucuronidase activity beside A5 3beta- and 17beta-hydroxysteroid dehydrogenase activities suggests that uropygial gland might be involved in sterols metabolism.
UVA, BIANCA MARIA, P. GHIANI, DEPLANO, STEFANIA, MANDICH, ALBERTA, L. VACCARI, VALLARINO, MAURO   +5 more
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Ozonolysis of 7-dehydrocholesterol acetate peroxide

Tetrahedron Letters, 1979
Abstract Secodione 3 and hemiacetal 4 from ozonolysis of peroxide 2 were obtained. A tentative mechanism of their formation is proposed.
J. Gumułka, W.J. Szczepek, Z. Wielogórski   +2 more
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Evaluation of cytotoxic effects of 7-dehydrocholesterol on melanoma cells

Free Radical Biology and Medicine, 2014
Ultraviolet radiation is the main cause of skin cancers, and melanoma is the most serious form of tumor. There is no therapy for advanced-stage melanoma and its metastasis because of their high resistance to various anticancer therapies. Human skin is an important metabolic organ in which occurs photoinduced synthesis of vitamin D3 from 7 ...
GELZO, MONICA, GRANATO, GIUSEPPINA, ALBANO, FRANCESCO, ARCUCCI, ALESSANDRO, DELLO RUSSO, ANTONIO, DE VENDITTIS, EMMANUELE, RUOCCO, MARIA ROSARIA, Corso G.   +7 more
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Inhibition of human fibroblasts sphingomyelinase by cholesterol and 7-dehydrocholesterol

Biochemical and Biophysical Research Communications, 1981
Abstract An inhibition of human fibroblast sphingomyelinase by cholesterol and 7-dehydrocholesterol is shown. This effect is obtained for cholesterol and 7-dehydrocholesterol/sphingomyelin molar ratios above 0.1. Diffusion measurements performed on mixed liposomes demonstrated for cholesterol/sphingomyelin and 7-dehydrocholesterol/sphingomyelin molar
J C, Maziere, C, Wolf, C, Maziere, L, Mora, G, Bereziat, J, Polonovski   +5 more
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